Pharmacological screening of the aqueous extract of Musanga cecropiodes.

abstract：:Two new triterpenoid estersaponins (1, 2) were isolated from the leaves of Pittosporum tobira 'Variegata' (Thunb.) W. T. Aiton, along with one known saponin (3) and one known flavonoid glycoside (4). Their structures were established by different spectroscopic methods including 1D and 2D NMR, UV, as well as ESI-MS ana...

journal_title：Fitoterapia

authors： El Dib RA,Eskander J,Mohamed MA,Mohammed NM

更新日期：2015-10-01 00:00:00

abstract：:Thirty-five crude extracts from 11 Panamanian plants, distributed in 10 genera and five families, were evaluated for their in vitro cytotoxicity. Four extracts exhibited an inhibition of cellular growth at IC(50) values lower than 25 microg/ml which was considered a significant activity. ...

journal_title：Fitoterapia

authors： Calderón AI,Terreaux C,Gupta MP,Hostettmann K

更新日期：2003-06-01 00:00:00

abstract：:Four new triterpenoids, sweriyunnangenin A (1), sweriyunnanosides A (2), B (3) and C (4), along with nineteen known compounds (5-23) were isolated from Swertia yunnanensis. Based on extensive spectroscopic analyses (1D- and 2D-NMR, HRESIMS, UV, IR, [α]D), the structures of sweriyunnangenin A (1), sweriyunnanosides A (...

journal_title：Fitoterapia

authors： Cao TW,Geng CA,Jiang FQ,Ma YB,He K,Zhou NJ,Zhang XM,Zhou J,Chen JJ

更新日期：2013-09-01 00:00:00

abstract：:This investigation focuses on the in vitro neuroactive properties of pinostrobin, a substituted flavanone from Cajanus cajan (L.) Millsp. of the Fabaceae family. We demonstrate that pinostrobin inhibits voltage-gated sodium channels of mammalian brain (IC(50)=23 µM) based on the ability of this substance to suppress t...

journal_title：Fitoterapia

authors： Nicholson RA,David LS,Pan RL,Liu XM

更新日期：2010-10-01 00:00:00

abstract：:Chemical investigation of the cultured polyspore-derived mycobionts of a Pseudopyrenula subnudata lichen led to the isolation of two new compounds, subnudatones A and B (1 and 2), together with four known compounds, 1-(2-hydroxy-1,2,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)ethanone (3), libertalide C (4)...

journal_title：Fitoterapia

authors： Duong TH,Nguyen HH,Le TT,Tran TN,Sichaem J,Nguyen TT,Nguyen TP,Mai DT,Nguyen HH,Le HD

更新日期：2020-04-01 00:00:00

abstract：:Three new phloroglucinols, baeckenones D-F (1-3), were obtained from the leaves of Indonesian Baeckea frutescens, along with the known unusual endoperoxide, phloroglucinol (4). The structures of the isolated compounds were elucidated by 1D and 2D NMR and HREIMS spectra. Furthermore, the stereochemistry of baeckenone D...

journal_title：Fitoterapia

authors： Nisa K,Ito T,Kodama T,Tanaka M,Okamoto Y,Asakawa Y,Imagawa H,Morita H

更新日期：2016-03-01 00:00:00

abstract：:It has been reported that icariin and icariside II, two flavonoid glycosides coming from herba epimedii, which have a closely structural relationship, show some pharmacological effects such as preventing osteoporosis, cancer and depression. The content of natural icariside II is very low in herba epimedii, but it is t...

journal_title：Fitoterapia

authors： Xia Q,Xu D,Huang Z,Liu J,Wang X,Wang X,Liu S

更新日期：2010-07-01 00:00:00

abstract：:A botanical natural product, AkseBio2, was evaluated for its larvicidal effect against Culex pipiens under laboratory conditions. The product exhibited strong larvicidal activity and caused >90% mortalities in both the young (first-second) and the older (third-fourth) larval stages of the species at 24 h at the doses ...

journal_title：Fitoterapia

authors： Cetin H,Erler F,Yanikoglu A

更新日期：2004-12-01 00:00:00

abstract：:The antioxidant activity of Agrimonia eupatoria (Agrimony) and Agrimonia procera (Fragrant agrimony) extracts was assessed by measuring in DPPH radical scavenging and ABTS(+) radical decolourisation reaction systems. Radical scavenging capacity of agrimony extracts varied in a wide range (9.1-97.5% in DPPH reaction an...

journal_title：Fitoterapia

authors： Venskutonis PR,Skemaite M,Ragazinskiene O

更新日期：2007-02-01 00:00:00

abstract：:Two new pentacyclic triterpenes named kirmanoic acid (1) and kurramanoic acid (2) have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei Hook. The structures of the two new compounds were assigned on the basis of their ¹H and ¹³C NMR spectra including two-dimensional NMR techniques...

journal_title：Fitoterapia

authors： Hussain J,Ur Rehman N,Hussain H,Al-Harrasi A,Ali L,Rizvi TS,Ahmad M,Mehjabeen

更新日期：2012-04-01 00:00:00

abstract：:Phytochemical studies on the ethanol extract of the aerial parts of Ecdysanthera rosea led to the isolation of three new compounds, hydroquinone diglycoside acyl esters, ecdysanrosin A (1) and sesquiterpene, 5β-hydroperoxycostic acid (2) and apocarotenoid, 2, 4, 7-trimethyl-2, 4, 6, 8-tetraene-dialdehyde (3). Their st...

journal_title：Fitoterapia

authors： Zhu X,Zhang Q,Kong L,Wang F,Luo S

更新日期：2010-10-01 00:00:00

abstract：:The composition of the essential oil of Lindera neesiana Kurz fruit was examined by GC-MS, (1)H, (13)C and bidimensional NMR techniques (HMQC, HMBC, COSY, TOCSY). Forty compounds were identified, representing approximately 86% of the oil: Z-citral (15.08%), E-citral (11.89%), eucalyptol (8.75%), citronellal (6.72%), a...

journal_title：Fitoterapia

authors： Comai S,Dall'Acqua S,Grillo A,Castagliuolo I,Gurung K,Innocenti G

更新日期：2010-01-01 00:00:00

abstract：:A new arylnaphthalene lignan, named furfuracin, was isolated from the leaves of Knema furfuracea (Myristicaceae), whereas 7 known compounds including (+)-trans-1,2-dihydrodehydroguaiaretic acid, fragransin A(2), biochanin A, gingkolic acid, anarcardic acid, 2-hydroxy-6-(12-phenyldodecyl)-benzoic acid and 2-hydroxy-6-(...

journal_title：Fitoterapia

authors： Rangkaew N,Suttisri R,Moriyasu M,Kawanishi K

更新日期：2009-09-01 00:00:00

abstract：:Two new dimeric diarylheptanoids, named Alpinin C (1) and D (2), a new natural product of diarylheptanoid (3) along with three known diarylheptanoids (4-6) were isolated from the rhizomes of Alpinia officinarum Hance. Their structures were elucidated based on extensive spectroscopic analyses (1D and 2D NMR, HRTOFMS, I...

journal_title：Fitoterapia

authors： Liu D,Liu YW,Guan FQ,Liang JY

更新日期：2014-07-01 00:00:00

abstract：:The methanolic extract of the Zanthoxylum rhetsa Roxb. stem bark, given by oral route to mice at doses of 250 and 500 mg/kg, significantly reduced the abdominal contraction induced by acetic acid and the diarrhoeal episodes induced by castor oil in mice. ...

journal_title：Fitoterapia

authors： Rahman MT,Alimuzzaman M,Ahmad S,Chowdhury AA

更新日期：2002-07-01 00:00:00

abstract：:The tea seed triterpene saponin (TS) from Camellia sinensis was found to exhibit better antitumor activity in vivo in S180 implanted ICR mice and QR inducing activity for hepa lclc7 cells respectively compared with the total tea seed saponin (TTS), hydrolysate of the TTS and tea seed flavonoid glycosides (TF). By bioa...

journal_title：Fitoterapia

authors： Li N,Ma ZJ,Chu Y,Wang Y,Li X

更新日期：2013-01-01 00:00:00

abstract：:Besides the unquestionable positive effects of solar exposure for human health, UV rays have been widely investigated for toxicology aspects related to excessive UVB and UVA doses, which involve sunburns, skin aging, DNA skin damage and tumorigenesis. At present, synthetic and mineral sunscreens are used to protect ag...

journal_title：Fitoterapia

authors： Radice M,Manfredini S,Ziosi P,Dissette V,Buso P,Fallacara A,Vertuani S

更新日期：2016-10-01 00:00:00

abstract：:Eight new flavonoids daemoflavans A-H, including two dimeric proanthocyanidins (1 and 2), four flavans (3-6), two 2-arylbenzofurans (7 and 8), along with nine known compounds (9-17), were isolated from the fruit of Daemonorops draco. Their structures, including the absolute configurations, were elucidated by extensive...

journal_title：Fitoterapia

authors： Wang YY,Dai YW,Cao J,Chen YT,Zhao CX,Jiang L

更新日期：2020-06-01 00:00:00

abstract：:Three new clerodane type diterpenoids (2-4), together with one known analogues (1), were isolated from the tuberous roots of Tinospora sagittata (Oliv.) Gagnep. Compound 3 is an unusual clerodane diterpenoid with the carbonyl functionality at C-3, which represents the first example from this diterpenoid compounds clas...

journal_title：Fitoterapia

authors： Zhang G,Ma H,Hu S,Xu H,Yang B,Yang Q,Xue Y,Cheng L,Jiang J,Zhang J,Wang F,Zhang Y

更新日期：2016-04-01 00:00:00

abstract：:Phytochemical investigation of Tephrosia vogelii seedpods led to the isolation of twelve compounds: vogelisoflavone A (1), vogelisoflavone B (2), isopongaflavone (3), onogenin, luteolin, 4',7-dihydroxy-3'-methoxyflavanone, trans-p-hydroxycinnamic acid, tephrosin, 2-methoxygliricidol, dehydrorotenone, 6a,12a-dehydro-α-...

journal_title：Fitoterapia

authors： Owor RO,Derese S,Bedane KG,Zühlke S,Ndakala A,Spiteller M

更新日期：2020-10-01 00:00:00

abstract：:Solanum nigrum L. (also called as European black nightshade) has been traditionally used as folk medicine and food in some regions. Phytochemical investigations of the immature fruits of S. nigrum yielded five steroidal alkaloid glycosides (1-5), including an unprecedented nor-spirosolane type steroidal alkaloid with ...

journal_title：Fitoterapia

authors： Xiang L,Wang Y,Yi X,He X

更新日期：2019-09-01 00:00:00

abstract：:Largely widespread in tropical countries, Ocimum gratissimum has been claimed for many uses in folk medicine. Recent research on its essential oils showed five chemotypes. An Indian chemotype, with a high level of ethyl cinnamate, presents, in vitro, an interesting spectrum of antifungal properties. ...

journal_title：Fitoterapia

authors： Dubey NK,Tiwari TN,Mandin D,Andriamboavonjy H,Chaumont JP

更新日期：2000-09-01 00:00:00

abstract：:Diplacone (1) and mimulone (2), two geranylated flavanones, have previously shown anti-inflammatory and antiradical activity in vitro. The present study aimed to evaluate their activity in vivo on a model of colitis induced in Wistar rats by an oral administration of dextran sulfate sodium (DSS). Diplacone (1) and mim...

journal_title：Fitoterapia

authors： Vochyánová Z,Bartošová L,Bujdáková V,Fictum P,Husník R,Suchý P,Šmejkal K,Hošek J

更新日期：2015-03-01 00:00:00

abstract：:Dichloromethane extract of propolis (DCME) originating from Pitcairn Island demonstrated potent cytotoxicity against triple-negative MDA-MB-231 human breast carcinoma cells. The results from MTT assay showed that DCME inhibits the growth of the cancer cells in a dose- and time-dependent manner and upon the cell growth...

journal_title：Fitoterapia

authors： Georgieva K,Trusheva B,Uzunova V,Stoyanova T,Valcheva V,Popova M,Tzoneva R,Bankova V

更新日期：2018-07-01 00:00:00

abstract：:Hydroxycinnamic acid amides of serotonin (HCAAS) [caffeoylserotonin (compound 1), p-coumaroylserotonin (compound 2), and feruloylserotonin (compound 3)] are secondary metabolites produced in plants. The aim of this study was to investigate the cytoprotective effects of HCAAS based on intracellular reactive oxygen radi...

journal_title：Fitoterapia

authors： Choi JY,Kim H,Choi YJ,Ishihara A,Back K,Lee SG

更新日期：2010-12-01 00:00:00

abstract：:In the present work, we reported the triterpenoids isolated from n-butanol fraction of Kadsura heteroclita which is a Tujia ethnomedicine with trivial name "Xuetong". This effort resulted in the isolation of six unpresented triterpenoids xuetongsu A-F (1-6), along with five known triterpenoids (7-11). The structures o...

journal_title：Fitoterapia

authors： Cao L,Li B,Shehla N,Gong LM,Jian YQ,Peng CY,Sheng WB,Liu LP,Cai X,Man RY,Liao DF,Zhu XQ,Choudhary MI,Rahman AU,Wang W

更新日期：2020-01-01 00:00:00

abstract：:Anti-nociceptive and anti-oedematogenic effects of the aqueous extract from the leaves of Erythrina velutina were tested through experimental models of nociception in mice and paw oedema induced by carrageenin in rats. The extract (300 and 600 mg/kg) did not change the carrageenin-induced paw oedema. In the hot plate ...

journal_title：Fitoterapia

authors： Marchioro M,Blank Mde F,Mourão RH,Antoniolli AR

更新日期：2005-12-01 00:00:00

abstract：:Two prenylated isoflavanones (1) and (2) were isolated from the stem bark of Lespedeza bicolor along with the known compounds ethyl caffeate, caffeic acid, protocatechuic acid, betulinic acid, betulin, beta-sitosterol and from the stem heartwood daidzein and isoliquiritigenin. ...

journal_title：Fitoterapia

authors： Maximov OB,Kulesh NI,Stepanenko LS,Dmitrenok PS

更新日期：2004-01-01 00:00:00

abstract：:Aconitum carmichaelii has been used in traditional Chinese medicine for treating various diseases for several thousand years. Based on the biosynthetic pathway of some alkaloids such as C19-diterpenoid alkaloids and obvious differences in alkaloid content between leaves of two A. carmichaelii varieties has been report...

journal_title：Fitoterapia

authors： Yang Y,Hu P,Zhou X,Wu P,Si X,Lu B,Zhu Y,Xia Y

更新日期：2020-01-01 00:00:00

abstract：:From the roots of Smilax bockii a new compound, 7-hydroxymethyl-1, 4, 5-trihydroxynaphthalene-4-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranoside, was isolated. The structure of the new compound was elucidated on the basis of spectroscopic methods. ...

journal_title：Fitoterapia

authors： Li X,Xu J,Zhang P,Li N,Meng DL

更新日期：2008-09-01 00:00:00