Abstract:
:In the present work, we reported the triterpenoids isolated from n-butanol fraction of Kadsura heteroclita which is a Tujia ethnomedicine with trivial name "Xuetong". This effort resulted in the isolation of six unpresented triterpenoids xuetongsu A-F (1-6), along with five known triterpenoids (7-11). The structures of the reported compounds were established on the 1D, and 2D NMR and HRESIMS spectra, along with CD spectroscopic analysis. Moreover, the absolute stereochemistry of compound 7 was determined by X-ray diffraction analysis. Antioxidant and cytotoxic activities were evaluated for all isolated compounds, compound 7 shown weak cytotoxic activity against HL-60 with IC50 value of 50.0 μM.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Cao L,Li B,Shehla N,Gong LM,Jian YQ,Peng CY,Sheng WB,Liu LP,Cai X,Man RY,Liao DF,Zhu XQ,Choudhary MI,Rahman AU,Wang Wdoi
10.1016/j.fitote.2019.104441subject
Has Abstractpub_date
2020-01-01 00:00:00pages
104441eissn
0367-326Xissn
1873-6971pii
S0367-326X(19)31761-7journal_volume
140pub_type
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