Abstract:
:A phytochemical investigation of the chloroform leaf extract of Alchornea latifolia has been undertaken. Along with the triterpenoids taraxerone, friedelin, epifriedelinol, and taraxerol, the plant also contains seco-3,4-friedelin (dihydroputranjivic acid) (1) and seco-3,4-taraxerone (2). These A-ring-opened triterpenoids show in vitro cytotoxic activity against Hep-G2 and A-431 human cancer cell lines and are potent inhibitors of topoisomerase II.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Setzer WN,Shen X,Bates RB,Burns JR,McClure KJ,Zhang P,Moriarity DM,Lawton ROdoi
10.1016/s0367-326x(99)00133-1keywords:
subject
Has Abstractpub_date
2000-04-01 00:00:00pages
195-8issue
2eissn
0367-326Xissn
1873-6971pii
S0367-326X(99)00133-1journal_volume
71pub_type
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