A phytochemical investigation of Alchornea latifolia.

Abstract:

:A phytochemical investigation of the chloroform leaf extract of Alchornea latifolia has been undertaken. Along with the triterpenoids taraxerone, friedelin, epifriedelinol, and taraxerol, the plant also contains seco-3,4-friedelin (dihydroputranjivic acid) (1) and seco-3,4-taraxerone (2). These A-ring-opened triterpenoids show in vitro cytotoxic activity against Hep-G2 and A-431 human cancer cell lines and are potent inhibitors of topoisomerase II.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Setzer WN,Shen X,Bates RB,Burns JR,McClure KJ,Zhang P,Moriarity DM,Lawton RO

doi

10.1016/s0367-326x(99)00133-1

keywords:

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

195-8

issue

2

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(99)00133-1

journal_volume

71

pub_type

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