Phytochemical compounds involved in the anti-inflammatory effect of propolis extract.

Abstract:

:Two ethanolic propolis extracts (EPE) with and without the caffeic acid phenethyl ester (CAPE), CAPE and galangin (major components of propolis) were investigated for anti-inflammatory activity in rats using carrageenin foot oedema, carrageenin pleurisy and adjuvant arthritis. In our experiments, EPE with CAPE and CAPE alone significantly inhibited carrageenin oedema, carrageenin pleurisy and adjuvant arthritis. In contrast EPE without CAPE and galangin did not exhibit anti-inflammatory effects in acute and chronic inflammation. These results suggest that the anti-inflammatory activity of propolis is due to CAPE.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Borrelli F,Maffia P,Pinto L,Ianaro A,Russo A,Capasso F,Ialenti A

doi

10.1016/s0367-326x(02)00191-0

keywords:

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

S53-63

eissn

0367-326X

issn

1873-6971

pii

S0367326X02001910

journal_volume

73 Suppl 1

pub_type

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