Abstract:
:Three new sesquiterpenoids, peniterpenoids A - C (1-3), together with six known metabolites (4-9) were isolated from an entomogenous fungus Penicillium janthinellum (LB1.20090001) collected from a wheat cyst nematode. The structures of the new compounds were elucidated based on NMR and HRESIMS spectroscopic analyses. The absolute configuration of the C-8 secondary alcohol of peniterpenoid B (2) was determined by [Rh2(OCOCF3)4]-induced ECD experiment. Subsequently, the antimicrobial and DPPH scavenging activities were determined. Compounds 6-8 exhibited moderate antibacterial activities against Staphylococcus aureus (CGMCC1.2465) with MIC values of 25.0, 50.0 and 12.5 μg/mL, respectively.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Liu S,Fan W,Ren J,Wang W,Liu X,Liang Y,Wei T,Li Edoi
10.1016/j.fitote.2020.104801subject
Has Abstractpub_date
2021-01-01 00:00:00pages
104801eissn
0367-326Xissn
1873-6971pii
S0367-326X(20)30383-Xjournal_volume
148pub_type
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