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Chemical constituents investigation of Daphne tangutica.

Abstract：

:A phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Two compounds out of these isolates are new daphne diterpene analogs, and their structures were established as 1,2 alpha-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, and 1,2 beta-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, respectively, on the basis of spectroscopic methods. Additionally, this is the first time that 13 known compounds have been isolated and identified from this traditional Tibetan medicinal plant.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Pan L,Zhang XF,Deng Y,Zhou Y,Wang H,Ding LS

doi

10.1016/j.fitote.2009.07.002

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

38-41

issue

1

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(09)00165-8

journal_volume

81

pub_type

杂志文章

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