Two new epimeric isopavine N-oxides from Meconopsis horridula var. racemosa.

abstract：:Piper laetispicum C.DC. (Piperaceae), is an endemic climbing, glabrous plant distributed in the southern part of China. A novel alkaloid amide, Laetispicine, from it has been proven to possess antidepressant activity. In this present study, antidepressant and antinociceptive effects of the ethyl acetate extract (EAE) ...

journal_title：Fitoterapia

authors： Xie H,Yan MC,Jin D,Liu JJ,Yu M,Dong D,Cai CC,Pan SL

更新日期：2011-10-01 00:00:00

abstract：:Investigation of the fruits of Khaya senegalensis resulted in the isolation of three new mexicanolide limonoids containing a rare conjugated diene lactone system named seneganolide A (1), 2-hydroxyseneganolide A (2) and 2-acetoxyseneganolide A (3). Two known limonoids, 3-deacetyl-7-deacetoxy-7-oxokhivorin (4) and meth...

journal_title：Fitoterapia

authors： Abdelgaleil SA,Iwagawa T,Doe M,Nakatani M

更新日期：2004-09-01 00:00:00

abstract：:Extracts of Lantana camara var. aculeata leaves were studied for their phytochemical constituents and termiticidal effects against adult termite workers. The 5% chloroform extract was found to be significantly effective against termite workers. ...

journal_title：Fitoterapia

authors： Verma RK,Verma SK

更新日期：2006-09-01 00:00:00

abstract：:Four new dihydrophenanthrenofuran, bleochranols A-D (1-4), along with 21 known compounds including phenanthrenes (5-14) and bibenzyls (15-25) were isolated and elucidated from the rhizomes of Bletilla ochracea. Combination of 1D/2D NMR techniques and the Electronic Circular Dichroism (ECD) spectroscopy based on the em...

journal_title：Fitoterapia

authors： Li JY,Kuang MT,Yang L,Kong QH,Hou B,Liu ZH,Chi XQ,Yuan MY,Hu JM,Zhou J

更新日期：2018-06-01 00:00:00

abstract：:The effects of the essential oil of Eucalyptus tereticornis (EOET), especially the effects of its constituents alpha- and beta-pinene, were studied on rat trachea in vitro. In tracheal rings, EOET, alpha- or beta-pinene potentiated the contractions induced by acetylcholine (ACh). Contractions induced by K(+) (60mM) we...

journal_title：Fitoterapia

authors： Lima FJ,Brito TS,Freire WB,Costa RC,Linhares MI,Sousa FC,Lahlou S,Leal-Cardoso JH,Santos AA,Magalhães PJ

更新日期：2010-09-01 00:00:00

abstract：:Four new lathyrane-type diterpenoids (1-4) and a novel macrocyclic diterpenoid (5) featuring a 5/7/7/4-fused ring system, together with seventeen known ones (6-22), were isolated from the seeds of Euphorbia lathyris. Their structures were elucidated by extensive spectroscopic analyses and single crystal X-ray crystall...

journal_title：Fitoterapia

authors： Zuo Q,Mu HY,Gong Q,Ding X,Wang W,Zhang HY,Zhao WM

更新日期：2021-01-26 00:00:00

abstract：:A new monodesmosidic spirostanol saponin, along with three known saponins was isolated from Agave macroacantha Zucc leaves. The structure of the new saponin was established as hecogenin-3-O-alpha-L-rhamnopyranosyl (1-->4) beta-D-xylopyranosyl (1-->3)[beta-D-glucopyranosyl (1-->2)] beta-D-glucopyranosyl (1-->4) beta-D-...

journal_title：Fitoterapia

authors： Eskander J,Lavaud C,Harakat D

更新日期：2010-07-01 00:00:00

abstract：:Psychotria is a complex genus whose neotropical species are known by the presence of glucosidic monoterpene indole alkaloids. These compounds are able to display a large range of effects on the central nervous system, such as anxiolytic, antidepressant, analgesic, and impairment of learning and memory acquisition. The...

journal_title：Fitoterapia

authors： Farias FM,Passos CS,Arbo MD,Barros DM,Gottfried C,Steffen VM,Henriques AT

更新日期：2012-09-01 00:00:00

abstract：:As a part of our ongoing search for plant-derived compounds that inhibit nitric oxide production, the methanol extract of the roots of Vladimiria souliei was found to show significant inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells. Bioactivity-guided isolation of the ex...

journal_title：Fitoterapia

authors： Xu J,Jin D,Shi D,Ma Y,Yang B,Zhao P,Guo Y

更新日期：2011-04-01 00:00:00

abstract：:Two triglycerides, both bearing polyunsaturated fatty acid residues, were isolated from the hexane extract of Urena lobata. One of them is characterized by the presence of three different polyunsaturated fatty acids. Their structures were studied with spectral methods. ...

journal_title：Fitoterapia

authors： Morelli CF,Cairoli P,Speranza G,Alamgir M,Rajia S

更新日期：2006-06-01 00:00:00

abstract：:Usually isolated from Garcinia (Clusiaceae) or Hypericum (Hypericaceae) species, some Polycyclic Polyprenylated AcylPhloroglucinols (PPAPs) have been recently reported as potential research tools for immunotherapy. Aiming at exploring the chemodiversity of PPAPs amongst Garcinia genus, a dereplication process suitable...

journal_title：Fitoterapia

authors： Bruguière A,Derbré S,Coste C,Le Bot M,Siegler B,Leong ST,Sulaiman SN,Awang K,Richomme P

更新日期：2018-11-01 00:00:00

abstract：:Three new phenylpropanoid derivatives, dasymaroacid A (1), dasymaroesters B and C (2 and 3), and one new polyoxygenated 6H-dibenzo[b,d]pyran-6-one derivative dasymarolactone D (4), together with seven known compounds (5-11), were isolated from the stems of Dasymaschalon rostratum Merr. Compounds 1 and 2 are unusual ph...

journal_title：Fitoterapia

authors： Yu ZX,Niu ZG,Li XB,Zheng CJ,Song XM,Chen GY,Song XP,Han CR,Wu SX

更新日期：2017-04-01 00:00:00

abstract：:The crude ethanol extract from the leaves of Zanthoxylum liebmannianum exhibited inhibitory effect on the reproduction of trophozoites of Entamoeba histolytica (IC(50)=3.48 microg/ml) and Giardia lamblia (IC(50)=58.00 microg/ml). From this extract, asarinin, hyperin, beta-sitosterol, and beta-sitosterol glucoside were...

journal_title：Fitoterapia

authors： Arrieta J,Reyes B,Calzada F,Cedillo-Rivera R,Navarrete A

更新日期：2001-03-01 00:00:00

abstract：:Three undescribed polycyclic polyprenylated acylphloroglucinols (PPAPs) and three tocotrienols derivatives, named as paucinochymol A-F (1-3 and 10-12), together with six known PPAPs, were isolated from the fruits of Garcinia paucinervis. Their structures and absolute configurations were determined by extensive NMR ana...

journal_title：Fitoterapia

authors： Tan X,Zhong F,Teng H,Li Q,Li Y,Mei Z,Chen Y,Yang G

更新日期：2020-10-01 00:00:00

abstract：:Two novel eremophylane acetophenone conjugates, colletotricholides A (1) and B (2), were isolated from the solid fermentation cultures of an endophytic fungus Colletotrichum gloeosporioides XL1200 isolated from the aerial parts of Salvia miltiorrhiza. The chemical structures of 1-2 were characterized by extensive spec...

journal_title：Fitoterapia

authors： Zhao WT,Liu QP,Chen HY,Zhao W,Gao Y,Yang XL

更新日期：2020-03-01 00:00:00

abstract：:Seven oleanane-type triterpenoid saponins, tunicosaponins B-D (1-3), F-I (4-7), along with eight known triterpenoid saponins (8-15), were isolated from the roots of Psammosilene tunicoides. The structures of compounds 1-7 were determined by comprehensive spectroscopic analysis, including 1D and 2D NMR techniques, mass...

journal_title：Fitoterapia

authors： Wen B,Tian JM,Huang ZR,Xiao SJ,Yuan WL,Wang JX,Li HL,Xu XK,Shen YH

更新日期：2020-07-01 00:00:00

abstract：:Four new naphthylisoquinoline alkaloids, the 5,8'-coupled ancistroyafungines A-C (1-3) and the 5,1'-linked ancistroyafungine D (4), have been isolated from the stem bark of an as yet unidentified Ancistrocladus (Ancistrocladaceae) liana recently discovered near the village Yafunga, in the North-Central region of the D...

journal_title：Fitoterapia

authors： Kavatsurwa SM,Lombe BK,Feineis D,Dibwe DF,Maharaj V,Awale S,Bringmann G

更新日期：2018-10-01 00:00:00

abstract：:Dragon's blood is a rare and precious traditional medicine used by different cultures since ancient times. However, studies on enhancing the rapid accumulation of dragon's blood in Dracaena cambodiana and determining its formation mechanism are unavailable. In this study, the activities of two fungi, namely, BJDC01 an...

journal_title：Fitoterapia

authors： Cui JL,Wang CL,Guo SX,Xiao PG,Wang ML

更新日期：2013-06-01 00:00:00

abstract：:Flos Chrysanthemi (the flower of Chrysanthemum morifolium Ramat.) is widely used in China as a food and traditional Chinese medicine for many diseases. Luteolin and apigenin are two main bioactive components in Flos Chrysanthemi, and chrysoeriol and diosmetin are two methylated metabolites of luteolin in vivo by cathe...

journal_title：Fitoterapia

authors： Chen Z,Kong S,Song F,Li L,Jiang H

更新日期：2012-12-01 00:00:00

abstract：:Five new 2-(2-phenylethyl)chromone derivatives (1-5), along with eleven known compounds (6-16) were isolated from Chinese agarwood. Their structures were elucidated by spectroscopic data (NMR, UV, IR, and MS) analyses and comparison of their spectroscopic and physical data with the literature values. The absolute conf...

journal_title：Fitoterapia

authors： Huo HX,Gu YF,Sun H,Zhang YF,Liu WJ,Zhu ZX,Shi SP,Song YL,Jin HW,Zhao YF,Tu PF,Li J

更新日期：2017-04-01 00:00:00

abstract：:Antioxidant activity of the ethanol extract of Erigeron breviscapus (EEEB) were studied by using neuron oxidative injury model induced by superoxide radical. EEEB at the dose of 10-140 mug/ml reduced significantly the lipid peroxidation levels and lactic dehydrogenase (LDH) release from neuron exposed to superoxide ra...

journal_title：Fitoterapia

authors： Liu H,Yang X,Ren T,Feng Y,Xu H

更新日期：2005-12-01 00:00:00

abstract：:The first chemical examination of roots of the traditionally used medicinal plant Talinum triangulare (Portulacaceae) from Nigeria led to the isolation of two new C-methylated flavonoids, 5,6-dimethoxy-7-hydroxy-8-methyl-flavone (1), 5,6-dimethoxy-8-methyl-2-phenyl-7H-1-benzopyran-7-one (2), and one new α-pyrone deriv...

journal_title：Fitoterapia

authors： Umeokoli BO,Muharini R,Okoye FB,Ajiwe VI,Akpuaka MU,Lin W,Liu Z,Proksch P

更新日期：2016-03-01 00:00:00

abstract：:A fast and efficient method for the isolation of the C-glucosidated xanthones mangiferin and isomangiferin from the South-African plant Cyclopia genistoides was developed for the first time. The procedure involved extraction, liquid-liquid partitioning with ethyl acetate and subsequent precipitation of mangiferin and ...

journal_title：Fitoterapia

authors： Kokotkiewicz A,Luczkiewicz M,Pawlowska J,Luczkiewicz P,Sowinski P,Witkowski J,Bryl E,Bucinski A

更新日期：2013-10-01 00:00:00

abstract：:The fruits of Piper tuberculatum Jacq yielded piperine S (1) and N-(12,13,14-trimethoxydihydrocinnamoyl)-delta(3)-piperidin-2-one (2). Their complete NMR analysis based on one- and two-dimensional experiments is reported. ...

journal_title：Fitoterapia

authors： de O Chaves MC,de F Júnior AG,de O Santos BV

更新日期：2003-02-01 00:00:00

abstract：:Largely widespread in tropical countries, Ocimum gratissimum has been claimed for many uses in folk medicine. Recent research on its essential oils showed five chemotypes. An Indian chemotype, with a high level of ethyl cinnamate, presents, in vitro, an interesting spectrum of antifungal properties. ...

journal_title：Fitoterapia

authors： Dubey NK,Tiwari TN,Mandin D,Andriamboavonjy H,Chaumont JP

更新日期：2000-09-01 00:00:00

abstract：:The isolation of cinchonicine-derived alkaloids epicinchonicinol (1), cinchonidicinol (2) and a mixture of dihydrocinchonicinol and dihydrocinchonidicinol (3) from the dried bark of Ladenbergia oblongifolia, is reported along with (1)H and (13)C-NMR data. ...

journal_title：Fitoterapia

authors： Okunade AL,Lewis WH,Elvin-Lewis MP,Casper SJ,Goldberg DE

更新日期：2001-08-01 00:00:00

abstract：:The antimicrobial and cytotoxic activities of six lignans isolated from the core and bark acetone extracts of Hibiscus cannabinus have been investigated. Two compounds (2 and 3) showed strong cytotoxic activity against HeLa, Hep-2 and A-549 cell lines while compound 5 showed moderate activity on HeLa cells when they w...

journal_title：Fitoterapia

authors： Moujir L,Seca AM,Silva AM,López MR,Padilla N,Cavaleiro JA,Neto CP

更新日期：2007-07-01 00:00:00

abstract：:Four new sesquiterpene lactones, named artemargyinolides A-D (1-4), and seven known sesquiterpenoids (5-11) were isolated from Artemisia argyi. Their structures were elucidated based on the extensive analysis of spectroscopic data. The absolute configuration of 1 was assigned by X-ray crystallographic analysis. Compou...

journal_title：Fitoterapia

authors： Zhang LB,Lv JL

更新日期：2019-11-01 00:00:00

abstract：:Activity-guided fractionation of the methanol extract of Vitis vinifera bark led to the isolation of epsilon-viniferin, ampelopcin A, vitisin A and vitisin B. Vitisin A and vitisin B showed a remarkable inhibitory activity against 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase with IC50 value of 42.1 microM...

journal_title：Fitoterapia

authors： Koo M,Kim SH,Lee N,Yoo MY,Ryu SY,Kwon DY,Kim YS

更新日期：2008-04-01 00:00:00

abstract：:The antinociceptive properties of the aqueous extract of Eupatorium buniifolium aerial parts were investigated in chemical and thermal models of nociception in mice. Oral doses of 250 and 500 mg/kg produced an inhibition of 42.3% and 73.9%, respectively, of the abdominal writhes induced by acetic acid in mice. This an...

journal_title：Fitoterapia

authors： Miño J,Muschietti L,Ferraro G,Martino V,Acevedo C

更新日期：2005-01-01 00:00:00