Effects of Erigeron breviscapus ethanol extract on neuronal oxidative injury induced by superoxide radical.

abstract：:Sarcandracoumarin (1), the first coumarin having a 1-phenylethyl substituent at the C-3 position, was isolated along with eleven known phenolic compounds from the water extract of Sarcandra glabra. Its structure was elucidated on the basis of spectroscopic data. Compound 1 exhibited moderate or weak cytotoxicity again...

journal_title：Fitoterapia

authors： Feng S,Xu L,Wu M,Hao J,Qiu SX,Wei X

更新日期：2010-09-01 00:00:00

abstract：:The Src-homology 2 domain-containing phosphatase 2 (SHP2), encoded by PTPN11, has been reported oncogenic tyrosine phosphatase associated with various tumors and played critical roles in many cell signaling events. Targeting SHP2 by small molecules may be a promising way for cancer therapy. Herein, a new abietane dite...

journal_title：Fitoterapia

authors： Liu DM,Cao ZX,Yan HL,Li W,Yang F,Zhao WJ,Diao QC,Tan YZ

更新日期：2020-03-01 00:00:00

abstract：:The antioxidant activity of the methanol extract of Hypericum triquetrifolium Turra (Hypericaceae) aerial part and of flavonoids isolated therein, I3,II8-biapigenin, quercetin-3-O-galactoside, kaempferol-3-O-glycoside, (-)-epicatechin and hypericin, was evaluated. The IC(50) resulted between 0.062 and 1 mg/ml. ...

journal_title：Fitoterapia

authors： Conforti F,Statti GA,Tundis R,Menichini F,Houghton P

更新日期：2002-10-01 00:00:00

abstract：:One new resveratrol analogue, 1-(3',4',5'-trimethoxyphenyl)-2-methoxy-2-(4″-methoxyphenyl)-ethane-1-ol (1), and two new prenylisoflavones, 4'-hydroxy-5,7-dimethoxy-6-(3-methyl-2-butenyl)-isoflavone (2), and derrubon 5-methyl ether (3), together with 17 known compounds including one new natural product, 5,7-dihydroxy-3...

journal_title：Fitoterapia

authors： Zhang HX,Lunga PK,Li ZJ,Dai Q,Du ZZ

更新日期：2014-06-01 00:00:00

abstract：:A new cyclopeptide, pulvpeptin A (1), two pairs of norlignan lignanosides, tamariscinosides G and H (2, 3), together with five known compounds (4-8) were isolated from Selaginella pulvinata. The structures were elucidated by spectroscopic data and chemical degradation. The activity of tamariscinoside G (2) was evaluat...

journal_title：Fitoterapia

authors： Lv H,Li Y,Zhu M,Luo M,Qi J,Yu Z,Zhang H,Guo Y,Tong S,Li H,Yan J

更新日期：2020-06-01 00:00:00

abstract：:The estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum and five fractions obtained by solid-phase extraction were investigated using estrogen-responsive bioassays, a yeast cell assay and the Ishikawa Var-I assay. The extract was found to exhibit significant estrogenic activity in both...

journal_title：Fitoterapia

authors： De Naeyer A,Pocock V,Milligan S,De Keukeleire D

更新日期：2005-01-01 00:00:00

abstract：:Four new dihydrophenanthrenofuran, bleochranols A-D (1-4), along with 21 known compounds including phenanthrenes (5-14) and bibenzyls (15-25) were isolated and elucidated from the rhizomes of Bletilla ochracea. Combination of 1D/2D NMR techniques and the Electronic Circular Dichroism (ECD) spectroscopy based on the em...

journal_title：Fitoterapia

authors： Li JY,Kuang MT,Yang L,Kong QH,Hou B,Liu ZH,Chi XQ,Yuan MY,Hu JM,Zhou J

更新日期：2018-06-01 00:00:00

abstract：:Curcuphenol is a sesquiterpene isolated from sponges and plants having several significant biological activities. The present study explored its effect on cell proliferation and apoptosis in Caco-2 human colon cancer cells. It was demonstrated that curcuphenol in concentrations in the range of 29-116 µg/ml inhibited c...

journal_title：Fitoterapia

authors： Rodrigo G,Almanza GR,Cheng Y,Peng J,Hamann M,Duan RD,Akesson B

更新日期：2010-10-01 00:00:00

abstract：:A new guanidine alkaloid, millaurine A (1), was isolated from the methanol extract of the seeds of Millettia laurentii. The structure of the new compound was elucidated on the basis of spectral analysis. ...

journal_title：Fitoterapia

authors： Ngamga D,Fanso Free SN,Tane P,Fomum ZT

更新日期：2007-04-01 00:00:00

abstract：:A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to identify and quantify the camptothecin quaternary derivative CPT8 for application in pharmacokinetics and tissue distribution studies. Rat plasma and tissue samples were extracted with methanol by using camptothecin as the internal sta...

journal_title：Fitoterapia

authors： Li Q,Zhu Q,Zhang X,Hua C,Deng X,Zhao T,Sun B

更新日期：2013-10-01 00:00:00

abstract：:Five new guaiane-type sesquiterpenoids were obtained from the roots of Daphne genkwa. Their gross structures were established by extensive spectroscopic analyses. Attempts on the assignment of the relative configurations were unsuccessful when based on the NOESY correlations. Therefore, NMR chemical shift calculations...

journal_title：Fitoterapia

authors： Wang J,Ren Q,Zhang YY,Guo R,Lin B,Huang XX,Song SJ

更新日期：2019-10-01 00:00:00

abstract：:A new steroidal alkaloid, (-)-veranigrine (1) was isolated from the roots and rhizomes of Veratrum nigrum L. By means of spectroscopic methods its structure was established as (20S, 25S)-iminocholesta-5,22(N)-diene-1beta,3beta-diol. ...

journal_title：Fitoterapia

authors： Christov V,Mikhova B,Selenge D

更新日期：2009-01-01 00:00:00

abstract：:Two new prenylated 4-phenylcoumarins, named kielcoumarin A (1) and kielcoumarin B (2) together with three known compounds, mammea B/BA (3), mammea B/BA cyclo F (4) and ferruol A (5), were obtained from stems and roots of Kielmeyera argentea (Calophyllaceae). Their structures were elucidated based on spectroscopic data...

journal_title：Fitoterapia

authors： Boness HVM,Santos NAS,Costa IB,Queiroz CKL,Marques EJ,El-Bachá RS,Cruz FG

更新日期：2021-01-27 00:00:00

abstract：:A simple, sensitive and accurate liquid chromatographic method with photodiode-array detection was developed for determination of dehydroevodiamine with detection wavelength at 368 nm and column temperature at 30 degrees C. The separation was carried out on an Agilent Zorbax SB-C(18) column (250 mm x 4.6 mm, 5 microm)...

journal_title：Fitoterapia

authors： Zhao Y,Zhou X,Chen HG,Gong XJ,Cai ZW,Zhou CY

更新日期：2009-10-01 00:00:00

abstract：:Two triglycerides, both bearing polyunsaturated fatty acid residues, were isolated from the hexane extract of Urena lobata. One of them is characterized by the presence of three different polyunsaturated fatty acids. Their structures were studied with spectral methods. ...

journal_title：Fitoterapia

authors： Morelli CF,Cairoli P,Speranza G,Alamgir M,Rajia S

更新日期：2006-06-01 00:00:00

abstract：:Six new triterpenoids, pseudolarins A-F (1-6), were isolated from the twigs of Pseudolarix amabilis, together with four known triterpenoids (7-10) and five known diterpenoids (11-15). Their structures were determined by extensive spectroscopic analysis, and the absolute configuration of 1 was assigned by single-crysta...

journal_title：Fitoterapia

authors： Lei C,Huang QH,Zhao T,Wang PP,Li JY,Li J,Hou AJ

更新日期：2019-11-01 00:00:00

abstract：:Two new xanthones: mangostanaxanthones I (3) and II (5) were isolated from the pericarp of Garcinia mangostana, along with four known xanthones: 9-hydroxycalabaxanthone (1), parvifolixanthone C (2), α-mangostin (4), and rubraxanthone (6). Their structures were elucidated on the basis of IR, UV, 1D, 2D NMR, and MS spec...

journal_title：Fitoterapia

authors： Mohamed GA,Ibrahim SR,Shaaban MI,Ross SA

更新日期：2014-10-01 00:00:00

abstract：:The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...

journal_title：Fitoterapia

authors： Chen TL,Zhang YB,Xu W,Kang TG,Yang XW

更新日期：2014-03-01 00:00:00

abstract：:Rapid micropropagation of Nepeta rtanjensis, N. sibirica and N. nervosa was performed. Qualitative and quantitative nepetalactone content in methanol extracts of in vitro grown plants was analysed by reverse-phase HPLC coupled with UV and MS detection. Only trans,cis-nepetalactone was detected in shoots of N. rtanjens...

journal_title：Fitoterapia

authors： Nestorović J,Misić D,Siler B,Soković M,Glamoclija J,Cirić A,Maksimović V,Grubisić D

更新日期：2010-09-01 00:00:00

abstract：:Eight new flavonoids daemoflavans A-H, including two dimeric proanthocyanidins (1 and 2), four flavans (3-6), two 2-arylbenzofurans (7 and 8), along with nine known compounds (9-17), were isolated from the fruit of Daemonorops draco. Their structures, including the absolute configurations, were elucidated by extensive...

journal_title：Fitoterapia

authors： Wang YY,Dai YW,Cao J,Chen YT,Zhao CX,Jiang L

更新日期：2020-06-01 00:00:00

abstract：:Two new atranones T and U (1 and 2), and three known analogues atranone B (3), atranone Q (4), and stachatranone C (5) were isolated from the toxigenic fungus Stachybotrys chartarum. Their structures and absolute configurations were elucidated by spectroscopic data and calculated ECD analyses. The cytotoxicities of al...

journal_title：Fitoterapia

authors： Qin YD,Fang FM,Zhou JJ,Wang RB,Xu SX,Li LH,Zhang HL

更新日期：2020-10-01 00:00:00

abstract：:Rats treated with 100 mg /kg/day of the Catharanthus roseus ethanol extract had high rate of wound contraction significantly decreased epithelization period, significant increase in dry weight and hydroxyproline content of the granulation tissue when compared with the controls. Wound contraction together with increase...

journal_title：Fitoterapia

authors： Nayak BS,Anderson M,Pinto Pereira LM

更新日期：2007-12-01 00:00:00

abstract：:Ten new highly oxygenated lanostane triterpenoids, stereinones A-J (1-10), were isolated from the fruiting bodies of the basidiomycete Stereum sp. Compounds 3 and 4 are structurally characterized as intact lanostane-type triterpenoids containing unusual 1,2-diketone functionality at C-11 and C-12, while compound 10 is...

journal_title：Fitoterapia

authors： Yao JN,Chen L,Chen HP,Zhao ZZ,Zhang SB,Huang Y,Tang Y,Isaka M,Li ZH,Feng T,Liu JK

更新日期：2018-03-01 00:00:00

abstract：:Zuojinwan, which consists of Rhizoma coptidis-Evodia rutaecarpa powder (6:1,g/g), is a traditional Chinese medicine (TCM) prescription, clinically used for the treatment of gastro-intestinal disorders. This study compared the pharmacokinetics of dehydroevodiamine and coptisine, the main active ingredients in Zuojinwan...

journal_title：Fitoterapia

authors： Yan R,Wang Y,Shen W,Liu Y,Di X

更新日期：2011-12-01 00:00:00

abstract：:A new triterpene glycoside (1) along with the known intercedenside B (2) was isolated from the sea cucumber Pseudocolochirus violaceus. Glycoside 1 was elucidated as 3-O-{6-O-sodiumsulfate-3-O-methyl-beta-D-glucopyranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-[beta-D-xylopyranosyl(1-->2)]-beta-D-quinovopyranosyl-(1-->2...

journal_title：Fitoterapia

authors： Zhang SY,Tang HF,Yi YH

更新日期：2007-06-01 00:00:00

abstract：:A new degraded limonoid, named isodictamdiol A (1), two known degraded limonoids (2, 3) and a new nature product of quinoline alkaloid (4) along with five known quinoline alkaloids (5-9) were isolated from the root bark of Dictamnus angustifolius G. Don ex Sweet.. Certain useful NMR data were generalized to determine ...

journal_title：Fitoterapia

authors： Sun JB,Qu W,Wang P,Wu FH,Wang LY,Liang JY

更新日期：2013-10-01 00:00:00

abstract：:Total sennosides concentration is a very important factor when rhubarb and senna will be used as crude drugs. However, one-step analytical technique for total sennosides has not been reported except HPLC. An enzyme-linked immunosorbent assay (ELISA) for total sennosides concentration by using the combination of anti-s...

journal_title：Fitoterapia

authors： Morinaga O,Uto T,Sakamoto S,Tanaka H,Shoyama Y

更新日期：2009-01-01 00:00:00

abstract：:The genus Cyclopia (Fabaceae family) includes a number of shrubs endemic to Cape Fynbos region of South Africa. The most common of these plants is Cyclopia intermedia E. Mey., used together with other Cyclopia species (mainly C. subternata and C. sessiliflora) to manufacture the honeybush herbal tea which has been pro...

journal_title：Fitoterapia

authors： Kokotkiewicz A,Luczkiewicz M

更新日期：2009-01-01 00:00:00

abstract：:A new altersolanol derivative, 4-dehydroxyaltersolanol A (9), along with two known sesquiterpenoids, (S)-7'-hydroxyabscisic acid (7) and (S)-abscisic acid (8) were obtained from the endophytic fungus, Nigrospora oryzae, isolated from leaves of Combretum dolichopetalum. The host plant yielded six known compounds includ...

journal_title：Fitoterapia

authors： Uzor PF,Ebrahim W,Osadebe PO,Nwodo JN,Okoye FB,Müller WE,Lin W,Liu Z,Proksch P

更新日期：2015-09-01 00:00:00

abstract：:Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and three of them were diastereomers for each other. Compounds 1-7 were evaluated f...

journal_title：Fitoterapia

authors： Meng D,Li X,Han L,Zhang L,An W,Li X

更新日期：2014-01-01 00:00:00