Abstract：
:Three new phenylpropanoid derivatives, dasymaroacid A (1), dasymaroesters B and C (2 and 3), and one new polyoxygenated 6H-dibenzo[b,d]pyran-6-one derivative dasymarolactone D (4), together with seven known compounds (5-11), were isolated from the stems of Dasymaschalon rostratum Merr. Compounds 1 and 2 are unusual phenylpropanoid derivatives with a polymethyl substituted cyclopentene conjugated diketone as a substituent, and 3 is a unique cinnamic acid detective with a polymethyl substituted cyclohexene conjugated triketone as a substituent. Their structures were elucidated by extensive spectroscopic methods and chemical method, and 4 was further confirmed by the single crystal X-ray diffraction method. Compounds 1-4 and 7 showed weak anti-HIV-1 activities with EC50 values ranged from 16.44 to 25.91μM.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Yu ZX,Niu ZG,Li XB,Zheng CJ,Song XM,Chen GY,Song XP,Han CR,Wu SXdoi
10.1016/j.fitote.2017.02.003subject
Has Abstractpub_date
2017-04-01 00:00:00pages
27-31eissn
0367-326Xissn
1873-6971pii
S0367-326X(17)30081-3journal_volume
118pub_type
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