Sauruchinenols A and B, unprecedented monocyclic diterpenes with new carbon skeleton from the aerial parts of Saururus chinensis.

abstract：:A new degraded limonoid, named isodictamdiol A (1), two known degraded limonoids (2, 3) and a new nature product of quinoline alkaloid (4) along with five known quinoline alkaloids (5-9) were isolated from the root bark of Dictamnus angustifolius G. Don ex Sweet.. Certain useful NMR data were generalized to determine ...

journal_title：Fitoterapia

authors： Sun JB,Qu W,Wang P,Wu FH,Wang LY,Liang JY

更新日期：2013-10-01 00:00:00

abstract：:Successive petroleum ether, dichloromethane and methanol extracts of Ajuga remota aerial parts were tested in vitro for their antifungal activity. The petroleum ether fraction was found to be the most effective against the tested pathogens. ...

journal_title：Fitoterapia

authors： Kariba RM

更新日期：2001-02-01 00:00:00

abstract：:Aqueous extract of Pteris multifida showed scavenging activities on DPPH, hydroxyl radicals and reducing power. ...

journal_title：Fitoterapia

authors： Wang TC,Ti MC,Lo SC,Yang CC

更新日期：2007-04-01 00:00:00

abstract：:Thirty-five crude extracts from 11 Panamanian plants, distributed in 10 genera and five families, were evaluated for their in vitro cytotoxicity. Four extracts exhibited an inhibition of cellular growth at IC(50) values lower than 25 microg/ml which was considered a significant activity. ...

journal_title：Fitoterapia

authors： Calderón AI,Terreaux C,Gupta MP,Hostettmann K

更新日期：2003-06-01 00:00:00

abstract：:The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml a...

journal_title：Fitoterapia

authors： Psotová J,Chlopcíková S,Miketová P,Simánek V

更新日期：2005-09-01 00:00:00

abstract：:Black carrot (Daucus carota L. ssp. sativus var. atrorubens Alef.) is a valuable source of carbohydrates, minerals and vitamins and contains also high amounts of anthocyanins giving the characteristic deep-purple color. These latter compounds are known as natural dyes used in the food and pharmaceutical industry that ...

journal_title：Fitoterapia

authors： Smeriglio A,Denaro M,Barreca D,D'Angelo V,Germanò MP,Trombetta D

更新日期：2018-01-01 00:00:00

abstract：:Malaria is one of the most devastating infectious diseases in the developing world. Until now, only one candidate malaria vaccine RTS,S/AS01 has shown modest protection in phase 3 trial in African infants. Hence the treatment of malaria still depends on the current chemotherapeutic drugs. Considering the resistance of...

journal_title：Fitoterapia

authors： Jin H,Xu Z,Cui K,Zhang T,Lu W,Huang J

更新日期：2014-04-01 00:00:00

abstract：:A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 ...

journal_title：Fitoterapia

authors： Li L,Deng X,Zhang L,Shu P,Qin M

更新日期：2011-06-01 00:00:00

abstract：:The methanolic extract and total alkaloids of the aerial parts of Glaucium oxylobum exhibited good activity against Microsporum gypseum, Microsporum canis, Trichophyton mentagrophytes and Epidermophyton floccosum. Four alkaloids, dicentrine, glaucine, protopine, and alpha-allocryptopine, were identified as the compoun...

journal_title：Fitoterapia

authors： Morteza-Semnani K,Amin G,Shidfar MR,Hadizadeh H,Shafiee A

更新日期：2003-07-01 00:00:00

abstract：:Isonuatigenin-3-O-beta-solatriose (1) was isolated from the roots of Solanum sisymbriifolium. Its structure was determined by spectroscopic methods. ...

journal_title：Fitoterapia

authors： Ferro EA,Alvarenga NL,Ibarrola DA,Hellión-Ibarrola MC,Ravelo AG

更新日期：2005-09-01 00:00:00

abstract：:Five vibralactone derivatives containing γ, δ, ε-lactone cores, namely vibralactones X (1), Y (2), and Z1-Z3 (3-5), together with the known vibralactone, have been isolated from cultures of the basidiomycete Boreostereum vibrans. Compounds 3-5 possessed a novel bis-γ-lactone group which was found in vibralactone deriv...

journal_title：Fitoterapia

authors： Duan KT,Li ZH,Yu X,Yuan QX,Wang WX,Li J,Chen HP,Feng T,Liu JK

更新日期：2018-07-01 00:00:00

abstract：:Aloe barbadensis Mill has been used as food and medicine for a long time. In order to investigate the chemical constituents of A. barbadensis and their inhibitory activities towards phosphodiesterase-4D (PDE4D), 70% methanol extract of the dried A. barbadensis powder was employed. Phytochemical investigation has led t...

journal_title：Fitoterapia

authors： Zhong J,Huang Y,Ding W,Wu X,Wan J,Luo H

更新日期：2013-12-01 00:00:00

abstract：:Bioassay-guided fractionation of the dichloromethane extract of the fungus Neofusicoccum austral SYSU-SKS024 led to the isolation of three new ethylnaphthoquinone derivatives, neofusnaphthoquinone A (1), 6-(1-methoxylethy1)-2,7-dimethoxyjuglone (2), (3R,4R)-3-methoxyl-botryosphaerone D (6), together with six known ana...

journal_title：Fitoterapia

authors： Cui H,Zhang H,Liu Y,Gu Q,Xu J,Huang X,She Z

更新日期：2018-03-01 00:00:00

abstract：:A series of novel myricetin derivatives containing benzimidazole skeleton were constructed. The structure of compound 4g was further corroborated via X-ray single crystal diffractometer. The antimicrobial bioassays showed that all compounds exhibited potent inhibitory activities against Xanthomonas axonopodis pv. Citr...

journal_title：Fitoterapia

authors： Chen M,Tang X,Liu T,Peng F,Zhou Q,Luo H,He M,Xue W

更新日期：2020-12-11 00:00:00

abstract：:Four new C18-diterpenoid alkaloids, weisaconitines A-D (1-4), were isolated from Aconitum weixiense. Based on extensive UV, IR, MS, 1D and 2D NMR analyses, their structures were elucidated as 8-O-ethyldolaconine (1), 4-demethylgenicunine B (2), 14-oxoaconosine (3), and 8-O-ethylaconosine (4). The analgesic activity of...

journal_title：Fitoterapia

authors： Zhao DK,Ai HL,Zi SH,Zhang LM,Yang SC,Guo HC,Shen Y,Chen YP,Chen JJ

更新日期：2013-12-01 00:00:00

abstract：:Two new ent-kaurene diterpenoids, 15α-acetoxyl-6,11α-epoxy-6α-hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7-olide (1), 15α-hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide (2), together with ten known compounds (5-14) were isolated from the leaves of Isodon rubescens. Their structures were elucidated mainly by ...

journal_title：Fitoterapia

authors： Xie RJ,Yan FL,Hai GF,Hou RJ,Ding MM,Bai YX

更新日期：2011-06-01 00:00:00

abstract：:Diterpene alkaloids neoline (1), napelline (2), isotalatizidine (3), karakoline (4), senbusine A (5), senbusine C (6), aconitine (7) and taurenine (8) were identified from Aconitum napellus L. subsp. firmum, four (2-4, 6) of which are reported for the first time from this plant. The structures were determined by means...

journal_title：Fitoterapia

authors： Kiss T,Orvos P,Bánsághi S,Forgo P,Jedlinszki N,Tálosi L,Hohmann J,Csupor D

更新日期：2013-10-01 00:00:00

abstract：:Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with a...

journal_title：Fitoterapia

authors： Ajaiyeoba EO,Onocha PA,Nwozo SO,Sama W

更新日期：2003-12-01 00:00:00

abstract：:One new phenanthrene, aphyllone A (1) and four new bibenzyl derivatives, aphyllone B (2) and aphyllals C-D (3-5), together with nine known compounds (6-14), were isolated from the stems of Dendrobium aphyllum (Roxb.) C. E. Fischer. The structures of these new compounds were elucidated by means of extensive spectroscop...

journal_title：Fitoterapia

authors： Yang D,Liu LY,Cheng ZQ,Xu FQ,Fan WW,Zi CT,Dong FW,Zhou J,Ding ZT,Hu JM

更新日期：2015-01-01 00:00:00

abstract：:Two new alkaloids, named stenine A (1) and stenine B (2), along with the known compounds neostenine (3), stenine (4) and neotuberostemonine (5), were isolated from the roots of Stemona sessilifolia. Their structures were elucidated by 1D- and 2D-NMR spectra and X-ray single-crystal diffraction experiment. Anti-acetylc...

journal_title：Fitoterapia

authors： Lai DH,Yang ZD,Xue WW,Sheng J,Shi Y,Yao XJ

更新日期：2013-09-01 00:00:00

abstract：:This investigation focuses on the in vitro neuroactive properties of pinostrobin, a substituted flavanone from Cajanus cajan (L.) Millsp. of the Fabaceae family. We demonstrate that pinostrobin inhibits voltage-gated sodium channels of mammalian brain (IC(50)=23 µM) based on the ability of this substance to suppress t...

journal_title：Fitoterapia

authors： Nicholson RA,David LS,Pan RL,Liu XM

更新日期：2010-10-01 00:00:00

abstract：:As a part of our ongoing search for plant-derived compounds that inhibit nitric oxide production, the methanol extract of the roots of Vladimiria souliei was found to show significant inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells. Bioactivity-guided isolation of the ex...

journal_title：Fitoterapia

authors： Xu J,Jin D,Shi D,Ma Y,Yang B,Zhao P,Guo Y

更新日期：2011-04-01 00:00:00

abstract：:Two pairs of enantiomers of flavonoid oligomers (1a and 1b, 2a and 2b) along with one known chalcone (3) were isolated from the rhizomes of Alpinia platychilus. Their structures were elucidated on the basis of spectroscopic data (MS and 1D/2D NMR). The absolute configurations of the flavonoid oligomers were establishe...

journal_title：Fitoterapia

authors： Shen CP,Luo JG,Yang MH,Kong LY

更新日期：2015-10-01 00:00:00

abstract：:Various parts of Derris elliptica, Derris indica and Derris trifoliata on fractionation with a number of solvents (petrol, dichloromethane, ethyl acetate, butanol and methanol) gave fractions which demonstrated a varied level of broad spectrum antibacterial activity. Good activity was exhibited by the methanol fractio...

journal_title：Fitoterapia

authors： Khan MR,Omoloso AD,Barewai Y

更新日期：2006-06-01 00:00:00

abstract：:Three new secoiridoid aglycones of (-)-swermusic acid A (1) and B (3), and (-)-swerimuslatone A (2), and four new secoiridoid glycosides of 6'-O-formylsweroside (4), 6'-O-formylgentiopicroside (5), 6'-O-acetylamarogentin (6) and 6'-O-acetylamaronitidin (7), along with 40 known compounds (8-47) were isolated from Swert...

journal_title：Fitoterapia

authors： Cao TW,Geng CA,Ma YB,Zhang XM,Zhou J,Tao YD,Chen JJ

更新日期：2015-04-01 00:00:00

abstract：:Two ethanolic propolis extracts (EPE) with and without the caffeic acid phenethyl ester (CAPE), CAPE and galangin (major components of propolis) were investigated for anti-inflammatory activity in rats using carrageenin foot oedema, carrageenin pleurisy and adjuvant arthritis. In our experiments, EPE with CAPE and CAP...

journal_title：Fitoterapia

authors： Borrelli F,Maffia P,Pinto L,Ianaro A,Russo A,Capasso F,Ialenti A

更新日期：2002-11-01 00:00:00

abstract：:The aqueous extract of the Cocculus hirsutus aerial parts (100 and 200 mg/kg, p.o.) showed significant diuretic activity and laxative effect in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. ...

journal_title：Fitoterapia

authors： Ganapaty S,Dash GK,Subburaju T,Suresh P

更新日期：2002-02-01 00:00:00

abstract：:A new phenylpropanoid glucoside and two new neolignans, namely (1S, 2R)-1-(3, 4, 5-trimethoxyphenyl)-3-(β-d-glucopyranosyloxy)-1, 2, 3-propanetriol (1), and (7R, 8R)-4, 7, 9, 9'-tetrahydroxy-3, 5, 3', 5'-tetramethoxy-8-4'-oxyneolignan 4-O-β-d-glucopyranoside (2) and 3', 9, 9'-trihydroxy-3, 5-dimethoxy-8-O-4'-neolignan...

journal_title：Fitoterapia

authors： Shu J,Liang F,Liang J,Liang Y,Li F,Shao F,Liu R,Huang H

更新日期：2015-07-01 00:00:00

abstract：:Panax ginseng is an indigenous medicinal herb and has traditionally been used among Asian population for relief of many human ailments. We investigated the prophylactic role of Korean P. ginseng extract (KG) against X-ray irradiation-induced emesis in an acute rat pica model. Rats were treated with KG (12.5, 25, 50 mg...

journal_title：Fitoterapia

authors： Balaji Raghavendran HR,Rekha S,Cho HK,Jang SS,Son CG

更新日期：2012-09-01 00:00:00

abstract：:Goniothalamus macrophyllus (Blume) Hook. f. & Thoms. is a plant widely distributed in Malaysia. The aim of this study is to identify compounds from the roots of G. macrophyllus. The ground roots were extracted with aqueous methanol and partitioned sequentially with n-hexane, chloroform and butanol. Purification from t...

journal_title：Fitoterapia

authors： Abdullah N,Sahibul-Anwar H,Ideris S,Hasuda T,Hitotsuyanagi Y,Takeya K,Diederich M,Choo C

更新日期：2013-07-01 00:00:00