Vibralactone derivatives containing γ, δ, ε-lactone cores from cultures of the basidiomycete Boreostereum vibrans.

Abstract:

:Five vibralactone derivatives containing γ, δ, ε-lactone cores, namely vibralactones X (1), Y (2), and Z1-Z3 (3-5), together with the known vibralactone, have been isolated from cultures of the basidiomycete Boreostereum vibrans. Compounds 3-5 possessed a novel bis-γ-lactone group which was found in vibralactone derivatives for the first time. Compounds 3 and 5 exhibited moderate cytotoxicities to human cancer cell lines referring to that of cisplatin.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Duan KT,Li ZH,Yu X,Yuan QX,Wang WX,Li J,Chen HP,Feng T,Liu JK

doi

10.1016/j.fitote.2018.04.020

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

7-11

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(18)30420-9

journal_volume

128

pub_type

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