Genus Alangium - A review on its traditional uses, phytochemistry and pharmacological activities.

Abstract:

:The species from Alangium have been used as folk medicine to treat rheumatism, skin diseases, diabetes by the people of Southeast Asia. Previous phytochemical studies have shown this genus are rich sources of alkaloids, glycosides, and terpenoids, which have attracted considerable attention of many researchers due to their markedly diverse and complex architecture. The crude extracts as well as the monomeric compounds from the title genus possess anti-tumor, anti-inflammatory, antibacterial, anti-oxidant pharmacological activities. Besides, some isolates from Alangium exhibited the effects on skeletal, smooth muscle and the nervous system. As a large genus of medicinal plants, the medicinal value of Alangium has been widely reported, but there is no review that provide a systematic summary towards its chemical constituents and pharmacological activities, to our knowledge. This work aims to present a comprehensive overview on the traditional uses, phytochemistry, and pharmacological activities of medicinal plants in the genus Alangium, and to explore the evidence supporting its ethnopharmacological effectiveness.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Hu XY,Wei X,Zhou YQ,Liu XW,Li JX,Zhang W,Wang CB,Zhang LY,Zhou Y

doi

10.1016/j.fitote.2020.104773

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

104773

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(20)30355-5

journal_volume

147

pub_type

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