Abstract:
:Three new steroidal glycosides (1-3) and a novel natural product 4 firstly obtained from a plant source, together with two known steroidal glycosides (5-6) have been isolated from the whole plant of Reineckia carnea. Their structures were determined by physicochemical properties and spectroscopic methods, and their cytotoxic activities against human 1299 tumor cells were evaluated by the MTT method. Compounds 4, 5 and 6 exhibited cytotoxicity with IC50 values of 50.3 μmol·L(-1), 67.2 μmol·L(-1) and 61.8 μmol·L(-1), while compounds 1, 2, and 3 showed no cytotoxicity with the cells.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Song X,Zhang D,He H,Li Y,Yang X,Deng C,Tang Z,Cui J,Yue Zdoi
10.1016/j.fitote.2015.07.008subject
Has Abstractpub_date
2015-09-01 00:00:00pages
240-5eissn
0367-326Xissn
1873-6971pii
S0367-326X(15)30044-7journal_volume
105pub_type
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