Steroidal glycosides from Reineckia carnea.

Abstract:

:Three new steroidal glycosides (1-3) and a novel natural product 4 firstly obtained from a plant source, together with two known steroidal glycosides (5-6) have been isolated from the whole plant of Reineckia carnea. Their structures were determined by physicochemical properties and spectroscopic methods, and their cytotoxic activities against human 1299 tumor cells were evaluated by the MTT method. Compounds 4, 5 and 6 exhibited cytotoxicity with IC50 values of 50.3 μmol·L(-1), 67.2 μmol·L(-1) and 61.8 μmol·L(-1), while compounds 1, 2, and 3 showed no cytotoxicity with the cells.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Song X,Zhang D,He H,Li Y,Yang X,Deng C,Tang Z,Cui J,Yue Z

doi

10.1016/j.fitote.2015.07.008

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

240-5

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(15)30044-7

journal_volume

105

pub_type

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