Toonasindiynes A-F, new polyacetylenes from Toona sinensis with cytotoxic and anti-inflammatory activities.

abstract：:Two new pentacyclic triterpenes named kirmanoic acid (1) and kurramanoic acid (2) have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei Hook. The structures of the two new compounds were assigned on the basis of their ¹H and ¹³C NMR spectra including two-dimensional NMR techniques...

journal_title：Fitoterapia

authors： Hussain J,Ur Rehman N,Hussain H,Al-Harrasi A,Ali L,Rizvi TS,Ahmad M,Mehjabeen

更新日期：2012-04-01 00:00:00

abstract：:The ethanolic extract of Lawsonia inermis leaves and lawsone tested for trypsin inhibitory activity showed an IC(50) value of 64.87 and 48.6 microg/ml, respectively. ...

journal_title：Fitoterapia

authors： Yogisha S,Samiulla DS,Prashanth D,Padmaja R,Amit A

更新日期：2002-12-01 00:00:00

abstract：:Biomass and secondary metabolite accumulation were assayed on a wide range of auxins, cytokinins and their combinations using Ecballium elaterium callus tissue. The best combination was that consisting of alpha-naphthalene acetic acid (NAA) and benzylamino purine (BAP) (1 mg/l of medium, each). NAA and BAP were set up...

journal_title：Fitoterapia

authors： Attard EG,Scicluna-Spiteri A

更新日期：2001-01-01 00:00:00

abstract：:7-O-methylvariecolortide A (1), variecolortide B (2), and variecolortide C (3), the rare variecolortides existing in racemic manner, were isolated from an endolichenic fungal strain Eurotium sp. (No. 17-11-8-1). With the chiral HPLC technology, (-)-(S)-7-O-methylvariecolortide A (1a), (+)-(R)-7-O-methylvariecolortide ...

journal_title：Fitoterapia

authors： Chen GD,Bao YR,Huang YF,Hu D,Li XX,Guo LD,Li J,Yao XS,Gao H

更新日期：2014-01-01 00:00:00

abstract：:The flavonoid baicalein has been demonstrated to be an activator of the transcription factor Nrf2 in mammalian cell lines. We show that it further modulates the Nrf2 homolog SKN-1 in Caenorhabditis elegans and by this pathway mediates beneficial effects in the nematode: baicalein enhances the resistance of C. elegans ...

journal_title：Fitoterapia

authors： Havermann S,Humpf HU,Wätjen W

更新日期：2016-09-01 00:00:00

abstract：:Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and three of them were diastereomers for each other. Compounds 1-7 were evaluated f...

journal_title：Fitoterapia

authors： Meng D,Li X,Han L,Zhang L,An W,Li X

更新日期：2014-01-01 00:00:00

abstract：:Rats treated with 100 mg /kg/day of the Catharanthus roseus ethanol extract had high rate of wound contraction significantly decreased epithelization period, significant increase in dry weight and hydroxyproline content of the granulation tissue when compared with the controls. Wound contraction together with increase...

journal_title：Fitoterapia

authors： Nayak BS,Anderson M,Pinto Pereira LM

更新日期：2007-12-01 00:00:00

abstract：:The irritant potential of total methanolic extract and five triterpenoids newly isolated from the leaves of Ficus carica investigated by open mouse ear assay. Total methanolic extract, calotropenyl acetate, methyl maslinate and lupeol acetate showed potent and persistent irritant effects. ...

journal_title：Fitoterapia

authors： Saeed MA,Sabir AW

更新日期：2002-08-01 00:00:00

abstract：:Phytochemical investigations on Physalis. alkekengi L. var. franchetii, a widespread traditional Chinese medicine, led to the isolation and identification of three new sesquiterpenoids physalisitins A-C (1-3). Their structures were elucidated by NMR and HRESIMS analysis, and their absolute configurations were determin...

journal_title：Fitoterapia

authors： Zhang JL,Zhou FF,Li YZ,Feng T,Jiang LL,Jiang RW,Zhang XX,Li XD

更新日期：2020-03-01 00:00:00

abstract：:Five new lanostane triterpenoids, ganoderic acid XL1 (1), ganoderic acid XL2 (2), 20-hydroxy-ganoderic acid AM1 (3), ganoderenic acid AM1 (4) and ganoderesin C (5), together with five known triterpenoids (6-10) were isolated from the fruiting bodies of Ganoderma theaecolum. Chemical structures were elucidated on the b...

journal_title：Fitoterapia

authors： Liu LY,Chen H,Liu C,Wang HQ,Kang J,Li Y,Chen RY

更新日期：2014-10-01 00:00:00

abstract：:Since the extract from berries of Aronia melanocarpa presents antioxidative properties in plasma and in blood platelets, not only from healthy group, but also from patients with benign breast diseases and in patients with invasive breast cancer before surgery, the aim of our present study was to evaluate the oxidative...

journal_title：Fitoterapia

authors： Kedzierska M,Olas B,Wachowicz B,Glowacki R,Bald E,Czernek U,Szydłowska-Pazera K,Potemski P,Piekarski J,Jeziorski A

更新日期：2012-03-01 00:00:00

abstract：:Acteoside, which belongs to the family of phenylethanoid glycosides (PhGs), has extensive biological activities, including strong antioxidant, anti-inflammatory, hepatoprotect, and cell apoptosis regulation. Like other PhGs compounds, the fate of acteoside in the gut for both parent polyphenols and their degradation p...

journal_title：Fitoterapia

authors： Su D,Li W,Xu Q,Liu Y,Song Y,Feng Y

更新日期：2016-07-01 00:00:00

abstract：:Although the nature-identical chemical compounds are cheaper, they not always repeat biological activity of plant origin natural chemical compounds, often react allergies and resistance of microorganisms. The aim of this study was to investigate effects of Juniperus communis origin α-pinene with different enantiomeric...

journal_title：Fitoterapia

authors： Ložienė K,Švedienė J,Paškevičius A,Raudonienė V,Sytar O,Kosyan A

更新日期：2018-06-01 00:00:00

abstract：:Piper laetispicum C.DC. (Piperaceae), is an endemic climbing, glabrous plant distributed in the southern part of China. A novel alkaloid amide, Laetispicine, from it has been proven to possess antidepressant activity. In this present study, antidepressant and antinociceptive effects of the ethyl acetate extract (EAE) ...

journal_title：Fitoterapia

authors： Xie H,Yan MC,Jin D,Liu JJ,Yu M,Dong D,Cai CC,Pan SL

更新日期：2011-10-01 00:00:00

abstract：:Panax ginseng is an indigenous medicinal herb and has traditionally been used among Asian population for relief of many human ailments. We investigated the prophylactic role of Korean P. ginseng extract (KG) against X-ray irradiation-induced emesis in an acute rat pica model. Rats were treated with KG (12.5, 25, 50 mg...

journal_title：Fitoterapia

authors： Balaji Raghavendran HR,Rekha S,Cho HK,Jang SS,Son CG

更新日期：2012-09-01 00:00:00

abstract：:Five new 8-9' linked neolignans conchigeranals A-E (1-5), together with three known compounds galanganal (6), galanganols A (7) and B (8), were isolated from the whole plant of Alpinia conchigera. Their structures were established by spectroscopic analysis, including 2D-NMR spectroscopic techniques. Cytotoxicities of ...

journal_title：Fitoterapia

authors： Xu JJ,Zeng GZ,Yang SC,Shen Y,Tan NH

更新日期：2013-12-01 00:00:00

abstract：:Dragon's blood is a rare and precious traditional medicine used by different cultures since ancient times. However, studies on enhancing the rapid accumulation of dragon's blood in Dracaena cambodiana and determining its formation mechanism are unavailable. In this study, the activities of two fungi, namely, BJDC01 an...

journal_title：Fitoterapia

authors： Cui JL,Wang CL,Guo SX,Xiao PG,Wang ML

更新日期：2013-06-01 00:00:00

abstract：:The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml a...

journal_title：Fitoterapia

authors： Psotová J,Chlopcíková S,Miketová P,Simánek V

更新日期：2005-09-01 00:00:00

abstract：:Illicium verum is a well known spice in traditional Indian system for its therapeutic potential. The present study was aimed to evaluate the acetylcholinesterase (AChE) and butyrylcholinesterase inhibitory (BChE) activity of standardized extracts of I. verum and its oil. Present study confirmed that anethole contribut...

journal_title：Fitoterapia

authors： Bhadra S,Mukherjee PK,Kumar NS,Bandyopadhyay A

更新日期：2011-04-01 00:00:00

abstract：:Natural products chemistry is the discipline that lies at the heart of modern pharmacognosy. The field encompasses qualitative and quantitative analytical tools that range from spectroscopy and spectrometry to chromatography. Among other things, modern research on crude botanicals is engaged in the discovery of the ph...

journal_title：Fitoterapia

authors： Betz JM,Brown PN,Roman MC

更新日期：2011-01-01 00:00:00

abstract：:The flavonoids are a heterogeneous group of ubiquitous plant polyphenols that abound in the human diet and are endowed with several biological activities, including immunomodulating and antioxidant activities. The bioactivity of flavonoids is tightly correlated with their chemical structure and action mechanisms, most...

journal_title：Fitoterapia

authors： Ielpo MT,Basile A,Miranda R,Moscatiello V,Nappo C,Sorbo S,Laghi E,Ricciardi MM,Ricciardi L,Vuotto ML

更新日期：2000-08-01 00:00:00

abstract：:Bioassay-directed separation of the chloroform extracts from the air-dried aerial part of Alhagi pseudalhagi (M.B.) led to the isolation of a new isoflavonolignan (1), together with five known isoflavones (2-6) (Fig. 1). Their structures were identified on the basis of spectral analysis of NMR, MS, IR, UV and CD spect...

journal_title：Fitoterapia

authors： Li N,Zhang G,Xiong Y,Makhabel B,Li X,Jia X

更新日期：2010-12-01 00:00:00

abstract：:A series of novel myricetin derivatives containing benzimidazole skeleton were constructed. The structure of compound 4g was further corroborated via X-ray single crystal diffractometer. The antimicrobial bioassays showed that all compounds exhibited potent inhibitory activities against Xanthomonas axonopodis pv. Citr...

journal_title：Fitoterapia

authors： Chen M,Tang X,Liu T,Peng F,Zhou Q,Luo H,He M,Xue W

更新日期：2020-12-11 00:00:00

abstract：:Hydroxysafflor yellow A (HSYA) is an active ingredient obtained from the flower of Carthamus tinctorius L. The present study investigated the effects of HSYA on lipopolysaccharide (LPS)-induced inflammatory signal transduction in human alveolar epithelial A549 cells. A549 cells stimulated with LPS were incubated with ...

journal_title：Fitoterapia

authors： Song L,Zhu Y,Jin M,Zang B

更新日期：2013-01-01 00:00:00

abstract：:Five new cadinene-type sesquiterpenes, hibiscusterpenes I-V (1-5), and six known compounds (6-11) have been isolated from the methanol extract of the stems and the twigs of Hibiscus tiliaceus. The structures of the new compounds were elucidated based on chemical and spectroscopic evidence. The absolute stereochemistry...

journal_title：Fitoterapia

authors： Μatsumoto T,Imahori D,Achiwa K,Saito Y,Ohta T,Yoshida T,Kojima N,Yamashita M,Nakayama Y,Watanabe T

更新日期：2020-04-01 00:00:00

abstract：:Three new phenylpropanoid derivatives, dasymaroacid A (1), dasymaroesters B and C (2 and 3), and one new polyoxygenated 6H-dibenzo[b,d]pyran-6-one derivative dasymarolactone D (4), together with seven known compounds (5-11), were isolated from the stems of Dasymaschalon rostratum Merr. Compounds 1 and 2 are unusual ph...

journal_title：Fitoterapia

authors： Yu ZX,Niu ZG,Li XB,Zheng CJ,Song XM,Chen GY,Song XP,Han CR,Wu SX

更新日期：2017-04-01 00:00:00

abstract：:A new sesquiterpene coumarin with a novel sesquiterpene carbon framework, Sinkiangenorin D, and ten known sesquiterpene coumarins were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds, including the relative stereochemistry, were elucidated on the basis of spectroscopic data. All of t...

journal_title：Fitoterapia

authors： Li G,Li X,Cao L,Zhang L,Shen L,Zhu J,Wang J,Si J

更新日期：2015-06-01 00:00:00

abstract：:Three new mixed terpenoids, tricycloalternarenes (TCAs) F-H (1-3), together with ten known tricycloalternarenes (4-13), were isolated from the Czapek's culture of an endophytic fungus Ulocladium sp. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data...

journal_title：Fitoterapia

authors： Wang QX,Bao L,Yang XL,Guo H,Ren B,Guo LD,Song FH,Wang WZ,Liu HW,Zhang LX

更新日期：2013-03-01 00:00:00

abstract：:A new sulfur-containing iridoid glucoside, named paederoside B, was isolated from the stems of Paederia scandens. The structure of the new compound was elucidated as paederosidyl paederosidate by spectral evidence. ...

journal_title：Fitoterapia

authors： Zou X,Peng S,Liu X,Bai B,Ding L

更新日期：2006-07-01 00:00:00

abstract：:Two new minor cyclopeptides, named japonicin A (1), japonicin B (2), were isolated from the whole plants of Sagina japonica (Caryophyllaceae). Their structures were determined as cyclo-(Pro(1)-Pro(2)-Leu(2)-Leu(1)-Phe(2)-Pro(3)-Gly-Ser-Phe(1)) (1) and cyclo-(Pro(1)-Ile-Tyr-Asp-Pro(2)-Phe(2)-Pro(3)-Phe(1)) (2) on the b...

journal_title：Fitoterapia

authors： Jia AQ,Tan NH,Zhou J

更新日期：2009-04-01 00:00:00