当前位置： SCI文献检索 > FITOTERAPIA期刊下所有文献 > Effects of the commercial extract of aronia on oxidative stress in blood platelets isolated from breast cancer patients after the surgery and various phases of the chemotherapy.

Effects of the commercial extract of aronia on oxidative stress in blood platelets isolated from breast cancer patients after the surgery and various phases of the chemotherapy.

Abstract：

:Since the extract from berries of Aronia melanocarpa presents antioxidative properties in plasma and in blood platelets, not only from healthy group, but also from patients with benign breast diseases and in patients with invasive breast cancer before surgery, the aim of our present study was to evaluate the oxidative stress by measuring the level of various biomarkers of this process such as the generation of superoxide anion radicals (O(2)(-·)), the amount of carbonyl groups and 3-nitrotyrosine in proteins or the amount of glutathione in blood platelets isolated from breast cancer patients after the surgery and after various phases of the chemotherapy in the presence of A. melanocarpa extract (Aronox) in vitro. We demonstrated in platelet proteins from patients with invasive breast cancer (after the surgery and after various phases of the chemotherapy) higher level of carbonyl groups than in control healthy group. The level of 3-nitrotyrosine in platelet proteins from patients with invasive breast cancer was also significantly higher than in healthy subject group. We observed an increase of other biomarkers of oxidative stress such as O(2)(-·) and a decrease of GSH in platelets from patients with breast cancer (after the surgery and after various phases of the chemotherapy) compared to the healthy group. In model system in vitro our results showed that the commercial extract from berries of A. melanocarpa due to antioxidant action, significantly reduced the oxidative/nitrative stress in platelets from patients with invasive breast cancer caused by the surgery and various phases of the chemotherapy.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Kedzierska M,Olas B,Wachowicz B,Glowacki R,Bald E,Czernek U,Szydłowska-Pazera K,Potemski P,Piekarski J,Jeziorski A

doi

10.1016/j.fitote.2011.11.007

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

310-7

issue

2

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(11)00283-8

journal_volume

83

pub_type

杂志文章

相关文献

FITOTERAPIA文献大全
  • Effect of nagilactone E on cell morphology and glucan biosynthesis in budding yeast Saccharomyces cerevisiae.

    abstract：:Nagilactones are norditerpene dilactones isolated from the root bark of Podocarpus nagi. Although nagilactone E has been reported to show antifungal activities, its activity is weaker than that of antifungals on the market. Nagilactone E enhances the antifungal activity of phenylpropanoids such as anethole and isosafr...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2018.05.003

    authors： Hayashi K,Yamaguchi Y,Ogita A,Tanaka T,Kubo I,Fujita KI

    更新日期：2018-07-01 00:00:00

  • Anti-hyperglycemic action of apigenin-6-C-β-fucopyranoside from Averrhoa carambola.

    abstract：:A stimulatory effect of apigenin-6-C-β-fucopyranoside (1) on glucose uptake was observed when rat soleus muscle was incubated with 1, 10 and 100 μM of this flavonoid glycoside. The presence of specific insulin signaling inhibitors, such as wortmannin, an inhibitor of phosphoinositide 3-kinase (PI3K), RO318220, an inhi...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2012.07.003

    authors： Cazarolli LH,Kappel VD,Pereira DF,Moresco HH,Brighente IM,Pizzolatti MG,Silva FR

    更新日期：2012-10-01 00:00:00

  • Toonasindiynes A-F, new polyacetylenes from Toona sinensis with cytotoxic and anti-inflammatory activities.

    abstract：:The plants of genus Toona are well known for diverse limonoid secondary metabolites, while polyacetylenes are rarely found from Toona species. In this work, six new polyacetylenes toonasindiynes A-F (1-6) and six known analogues (7-12) were isolated from the root bark of Toona sinensis. Their structures and absolute c...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2020.104667

    authors： Xu WJ,Li JH,Zhou MM,Luo J,Jian KL,Tian XM,Xia YZ,Yang L,Luo J,Kong LY

    更新日期：2020-10-01 00:00:00

  • Metabolism mediated interaction of α-asarone and Acorus calamus with CYP3A4 and CYP2D6.

    abstract：:The present study was aimed to investigate the possible interaction of the standardized extract of Acorus calamus (AC) with Cytochrome P450 enzyme, quantitative determination of the α-asarone in the AC rhizome was performed by RP-HPLC method. In vitro interaction of the plant extract was evaluated by CYP450-carbon mon...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2010.11.009

    authors： Pandit S,Mukherjee PK,Ponnusankar S,Venkatesh M,Srikanth N

    更新日期：2011-04-01 00:00:00

  • Novel tirucallane triterpenoids from the stem bark of Toona sinensis.

    abstract：:Phytochemical investigation on the stem bark of Toona sinensis was carried out by various chromatographic techniques resulting in the isolation and elucidation of two novel tirucallane triterpenoids, named (20S)-3-oxo-tirucalla-25-nor-7-en-24-oic acid (1) and (20S)-5α,8α-epidioxy-3-oxo-24-nor-6.9(11)-dien-23-oic acid ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2016.05.009

    authors： Tang J,Xu J,Zhang J,Liu WY,Xie N,Chen L,Feng F,Qu W

    更新日期：2016-07-01 00:00:00

  • Traditional phytotherapy of the Albanians of Lepushe, Northern Albanian Alps.

    abstract：:An ethnobotanical and ethnopharmacognostic survey has been carried out in one of the most isolated mountainous area in Europe: the village of Lepushe and its surrounding territory, in the Northern Albanian Alps. Approximately 70 botanical taxa and 160 preparations, mainly derived from plants, but also derived from ani...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2005.03.015

    authors： Pieroni A,Dibra B,Grishaj G,Grishaj I,Gjon Maçai S

    更新日期：2005-06-01 00:00:00

  • Reducing effect of an extract of Phaseolus vulgaris on food intake in mice--focus on highly palatable foods.

    abstract：:Different lines of experimental evidence indicate that treatment with extracts from and derivatives of Phaseolus vulgaris reduces intake of food, including highly palatable foods and beverages, in rats. The present study was designed to extend to mice these lines of evidence. To this end, CD1 mice were treated acutely...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2012.12.015

    authors： Loi B,Fantini N,Colombo G,Gessa GL,Riva A,Bombardelli E,Morazzoni P,Carai MA

    更新日期：2013-03-01 00:00:00

  • Peniterpenoids A-C, new sesquiterpenoid metabolites from a wheat cyst nematode Penicillium janthinellum.

    abstract：:Three new sesquiterpenoids, peniterpenoids A - C (1-3), together with six known metabolites (4-9) were isolated from an entomogenous fungus Penicillium janthinellum (LB1.20090001) collected from a wheat cyst nematode. The structures of the new compounds were elucidated based on NMR and HRESIMS spectroscopic analyses. ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2020.104801

    authors： Liu S,Fan W,Ren J,Wang W,Liu X,Liang Y,Wei T,Li E

    更新日期：2021-01-01 00:00:00

  • Ursene type nortriterpene from Debregeasia salicifolia.

    abstract：:A new triterpene, 3beta-19alpha-dihydroxy-30-norurs-12-ene (1), has been isolated from the methanolic extract of Debregeasia salicifolia stems. Its structure has been elucidated with the help of one- and two-dimensional NMR and NOE studies. Lupeol, beta-sitosterol, stigmasterol and oleanolic acid are also reported for...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/s0367-326x(00)00338-5

    authors： Akbar E,Riaz M,Malik A

    更新日期：2001-05-01 00:00:00

  • 2-(2-Phenylethyl)chromone derivatives in artificial agarwood from Aquilaria sinensis.

    abstract：:Seven new 2-(2-phenylethyl)chromone derivatives (1-7) including a chlorinated one (4), together with eight known ones (8-15), were isolated from the EtOAc extract of artificial agarwood originating from Aquilaria sinensis (Lour.) Gilg. All structures including the absolute configurations were unambiguously elucidated ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2016.01.011

    authors： Liao G,Mei WL,Dong WH,Li W,Wang P,Kong FD,Gai CJ,Song XQ,Dai HF

    更新日期：2016-04-01 00:00:00

  • Bioactivity-guided chemical analysis of Melia azedarach L. (Meliaceae), displaying antidiabetic activity.

    abstract：:One new Euphane-type triterpenoid 3β-hydroxytirucalla-5, 24-dien-21-oic acid (1), and ten known compounds (2-11) were isolated from Melia azedarach L. through bioassay-guided chemical analysis. The structures of the isolated compounds were established by means of 1D and 2D NMR spectroscopic ((1)H, (13)C, DEPT, COSY, H...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2014.07.014

    authors： Khan MF,Rawat AK,Pawar B,Gautam S,Srivastava AK,Negi DS

    更新日期：2014-10-01 00:00:00

  • Atranones from Stachybotrys chartarum and their antitumor activities in MG-63 human osteosarcoma cells.

    abstract：:Two new atranones T and U (1 and 2), and three known analogues atranone B (3), atranone Q (4), and stachatranone C (5) were isolated from the toxigenic fungus Stachybotrys chartarum. Their structures and absolute configurations were elucidated by spectroscopic data and calculated ECD analyses. The cytotoxicities of al...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2020.104727

    authors： Qin YD,Fang FM,Zhou JJ,Wang RB,Xu SX,Li LH,Zhang HL

    更新日期：2020-10-01 00:00:00

  • A new eudesmane derivative from Onopordon ambiguum.

    abstract：:Reinvestigation of Onopordon ambiguum extract afforded a new eudesmane derivative 1, in addition to the known elemanoid derivative 2. The structures of both compounds were determined by spectroscopic techniques, including 1H-, 13C-NMR, DEPT, 1H-1H and 1H-13C COSY analysis. ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/s0367-326x(01)00366-5

    authors： El-Moghazy SA,Ahmed AA,Abdel-Ghani HF,El-Shanawany MA

    更新日期：2002-02-01 00:00:00

  • Cassia occidentalis L.: a review on its ethnobotany, phytochemical and pharmacological profile.

    abstract：:Cassia occidentalis L. is an annual or perennial Ayurvedic plant which is used in several traditional medicines to cure various diseases. This weed has been known to possess antibacterial, antifungal, antidiabetic, anti-inflammatory, anticancerous, antimutagenic and hepatoprotective activity. A wide range of chemical ...

    journal_title：Fitoterapia

    pub_type： 杂志文章,评审

    doi：10.1016/j.fitote.2009.09.008

    authors： Yadav JP,Arya V,Yadav S,Panghal M,Kumar S,Dhankhar S

    更新日期：2010-06-01 00:00:00

  • Chemical structures, production and enzymatic transformations of sapogenins and saponins from Centella asiatica (L.) Urban.

    abstract：:Centella asiatica (L.) Urban is a medicinal herb traditionally used in Asiatic countries for its multiple therapeutic properties, essentially due to its accumulation of specific pentacylic triterpenoid saponins, mainly asiaticoside and madecassoside and the corresponding sapogenins. This review summarizes the updated ...

    journal_title：Fitoterapia

    pub_type： 杂志文章,评审

    doi：10.1016/j.fitote.2016.07.011

    authors： Azerad R

    更新日期：2016-10-01 00:00:00

  • Antimicrobial activity of Horsfieldia helwigii and Melia azedarach.

    abstract：:The methanol extracts of leaves, root and stem barks of Horsfieldia helwigii and Melia azedarach showed a broad spectrum of antibacterial activity. The activity was increased on fractionation (petrol, dichloromethane, ethyl acetate), particularly in the petrol fraction of the leaves of H. helwigii and dichlorometane f...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/s0367-326x(00)00334-8

    authors： Khan MR,Kihara M,Omoloso AD

    更新日期：2001-05-01 00:00:00

  • Atrichodermones A-C, three new secondary metabolites from the solid culture of an endophytic fungal strain, Trichoderma atroviride.

    abstract：:An endophytic fungal strain named Trichoderma atroviride was isolated from the bulb of Lycoris radiata. Following cultivation on rice medium, a novel 3-amino-5-hydroxy-5-vinyl-2-cyclopenten-1-one dimer, atrichodermone A (1), a new cyclopentenone derivative, atrichodermone B (2), and a new sesquiterpene, atrichodermone...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2017.09.012

    authors： Zhou P,Wu Z,Tan D,Yang J,Zhou Q,Zeng F,Zhang M,Bie Q,Chen C,Xue Y,Luo Z,Wang J,Zhu H,Zhang Y

    更新日期：2017-11-01 00:00:00

  • Cytotoxic lignans from fruits of Cleistanthus tonkinensis.

    abstract：:Seven new lignans, cleistonkinins A- E (1-5), cleistonkisides A and B (6-7) were isolated from the fruits of Cleistanthus tonkinensis (Euphorbiaceae), together with five known aryltetralin lignans, cleisindoside B (8), cleistantoxin (9), cleisindoside D (10), neocleistantoxin (11) and polygamain (12). Their structures...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2019.104432

    authors： Nguyen LH,Vu VN,Phi Thi D,Tran VH,Litaudon M,Roussi F,Nguyen VH,Chau VM,Doan Thi Mai H,Pham VC

    更新日期：2020-01-01 00:00:00

  • Baicalein modulates stress-resistance and life span in C. elegans via SKN-1 but not DAF-16.

    abstract：:The flavonoid baicalein has been demonstrated to be an activator of the transcription factor Nrf2 in mammalian cell lines. We show that it further modulates the Nrf2 homolog SKN-1 in Caenorhabditis elegans and by this pathway mediates beneficial effects in the nematode: baicalein enhances the resistance of C. elegans ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2016.06.018

    authors： Havermann S,Humpf HU,Wätjen W

    更新日期：2016-09-01 00:00:00

  • Herbal extracts, lichens and biomolecules as natural photo-protection alternatives to synthetic UV filters. A systematic review.

    abstract：:Besides the unquestionable positive effects of solar exposure for human health, UV rays have been widely investigated for toxicology aspects related to excessive UVB and UVA doses, which involve sunburns, skin aging, DNA skin damage and tumorigenesis. At present, synthetic and mineral sunscreens are used to protect ag...

    journal_title：Fitoterapia

    pub_type： 杂志文章,评审

    doi：10.1016/j.fitote.2016.09.003

    authors： Radice M,Manfredini S,Ziosi P,Dissette V,Buso P,Fallacara A,Vertuani S

    更新日期：2016-10-01 00:00:00

  • Anti-Obesity effects of protopanaxdiol types of Ginsenosides isolated from the leaves of American ginseng (Panax quinquefolius L.) in mice fed with a high-fat diet.

    abstract：:Effects of protopanaxdiol (PDG) and protopanaxatriol (PTG) types of ginsenosides isolated from the leaves of American ginseng on porcine pancreatic lipase activity were determined in vitro. PDG inhibited the pancreatic lipase activity in a dose-dependent manner at the concentrations of 0.25-1mg/ml. It inhibited hydrol...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2010.07.002

    authors： Liu R,Zhang J,Liu W,Kimura Y,Zheng Y

    更新日期：2010-12-01 00:00:00

  • Studies on the immunomodulatory activity of flavonoidal fraction of Tephrosia purpurea.

    abstract：:The flavonoid fraction of Tephrosia purpurea (FFTP) was studied for its effect on cellular and humoral functions and on macrophage phagocytosis in mice. Oral administration of FFTP (10-40 mg/kg) significantly inhibited sheep red blood cells (SRBC)-induced delayed-type hypersensitivity reactions. It also produced a sig...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/s0367-326x(03)00042-x

    authors： Damre AS,Gokhale AB,Phadke AS,Kulkarni KR,Saraf MN

    更新日期：2003-04-01 00:00:00

  • Five new benzylphenanthrenes from Cremastra appendiculata.

    abstract：:Five new benzylphenanthrenes, cremaphenanthrenes L-P (1-5) were isolated from the EtOAc-soluble extract of the tubers of Cremastra appendiculata. Their structures were elucidated based on the spectroscopic data and chemical methods. Compounds 1-5 were tested in vitro for their cytotoxic effects against colon (HCT-116)...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2015.03.003

    authors： Liu L,Li J,Zeng KW,Jiang Y,Tu PF

    更新日期：2015-06-01 00:00:00

  • Millaurine A, a new guanidine alkaloid from seeds of Millettia laurentii.

    abstract：:A new guanidine alkaloid, millaurine A (1), was isolated from the methanol extract of the seeds of Millettia laurentii. The structure of the new compound was elucidated on the basis of spectral analysis. ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2006.11.018

    authors： Ngamga D,Fanso Free SN,Tane P,Fomum ZT

    更新日期：2007-04-01 00:00:00

  • Evaluation of wound-healing potential of Catharanthus roseus leaf extract in rats.

    abstract：:Rats treated with 100 mg /kg/day of the Catharanthus roseus ethanol extract had high rate of wound contraction significantly decreased epithelization period, significant increase in dry weight and hydroxyproline content of the granulation tissue when compared with the controls. Wound contraction together with increase...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2007.06.008

    authors： Nayak BS,Anderson M,Pinto Pereira LM

    更新日期：2007-12-01 00:00:00

  • New cycloartane triterpenes from bioactive extract of propolis from Pitcairn Island.

    abstract：:Dichloromethane extract of propolis (DCME) originating from Pitcairn Island demonstrated potent cytotoxicity against triple-negative MDA-MB-231 human breast carcinoma cells. The results from MTT assay showed that DCME inhibits the growth of the cancer cells in a dose- and time-dependent manner and upon the cell growth...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2018.05.024

    authors： Georgieva K,Trusheva B,Uzunova V,Stoyanova T,Valcheva V,Popova M,Tzoneva R,Bankova V

    更新日期：2018-07-01 00:00:00

  • New phenylpropanoid and 6H-dibenzo[b,d]pyran-6-one derivatives from the stems of Dasymaschalon rostratum.

    abstract：:Three new phenylpropanoid derivatives, dasymaroacid A (1), dasymaroesters B and C (2 and 3), and one new polyoxygenated 6H-dibenzo[b,d]pyran-6-one derivative dasymarolactone D (4), together with seven known compounds (5-11), were isolated from the stems of Dasymaschalon rostratum Merr. Compounds 1 and 2 are unusual ph...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2017.02.003

    authors： Yu ZX,Niu ZG,Li XB,Zheng CJ,Song XM,Chen GY,Song XP,Han CR,Wu SX

    更新日期：2017-04-01 00:00:00

  • Antiproliferative effects of curcuphenol, a sesquiterpene phenol.

    abstract：:Curcuphenol is a sesquiterpene isolated from sponges and plants having several significant biological activities. The present study explored its effect on cell proliferation and apoptosis in Caco-2 human colon cancer cells. It was demonstrated that curcuphenol in concentrations in the range of 29-116 µg/ml inhibited c...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2010.04.001

    authors： Rodrigo G,Almanza GR,Cheng Y,Peng J,Hamann M,Duan RD,Akesson B

    更新日期：2010-10-01 00:00:00

  • Sequence characterized amplified region (SCAR) analysis on DNA from the three medicinal Echinacea species.

    abstract：:In our previous study, RAPD (Random Amplified Polymorphic DNA) analysis revealed species-specific markers for three medicinal Echinacea species (Asteraceae): E. angustifolia DC., E. pallida (Nutt.) Nutt. and E. purpurea (L.) Moench. In the present work, we have converted a RAPD marker (750 bp) for E. purpurea into a S...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2006.09.012

    authors： Adinolfi B,Chicca A,Martinotti E,Breschi MC,Nieri P

    更新日期：2007-01-01 00:00:00

  • New flavonoids, emarginin A-C from Vaccinium emarginatum Hayata.

    abstract：:Phytochemical investigation of methanolic extract of the whole plants of Vaccinium emarginatum allowed for the characterization of one epicatechin derivative (1) that was isolated from a natural source for the first time and three new flavonoids, emarginin A (2), emarginin B (3), and emarginin C (4), together with 11 ...

    journal_title：Fitoterapia

    pub_type： 杂志文章

    doi：10.1016/j.fitote.2019.104446

    authors： Tu PC,Liang YC,Huang GJ,Huang HC,Kao MC,Lu TL,Kuo YH

    更新日期：2020-03-01 00:00:00