Abstract:
:The flavonoid fraction of Tephrosia purpurea (FFTP) was studied for its effect on cellular and humoral functions and on macrophage phagocytosis in mice. Oral administration of FFTP (10-40 mg/kg) significantly inhibited sheep red blood cells (SRBC)-induced delayed-type hypersensitivity reactions. It also produced a significant, dose-related decrease in sheep erythrocyte-specific haemagglutination antibody titre. However, the fraction failed to show a significant change in the macrophage phagocytic activity. The results obtained indicate the ability of the flavonoidal fraction of T. purpurea to modulate both the cell-mediated and the humoral components of the immune system.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Damre AS,Gokhale AB,Phadke AS,Kulkarni KR,Saraf MNdoi
10.1016/s0367-326x(03)00042-xkeywords:
subject
Has Abstractpub_date
2003-04-01 00:00:00pages
257-61issue
3eissn
0367-326Xissn
1873-6971pii
S0367326X0300042Xjournal_volume
74pub_type
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