New isoflavonolignan with quinone reductase inducing activity from Alhagi pseudalhagi (M.B.).

abstract：:6,7-Dimethylesculetin (D), geniposide (G) and rhein (R) are the three major active ingredients of Yin-Chen-Hao-Tang (YCHT), a famous Chinese herbal formula, which has been shown to be clinically effective for treating hepatic injury (HI) syndrome. The present study was conducted to investigate the therapeutic and syne...

journal_title：Fitoterapia

authors： Zhang A,Sun H,Yuan Y,Sun W,Jiao G,Wang X

更新日期：2011-12-01 00:00:00

abstract：:A new lathyrane diterpene (1), an unreported spectroscopic data lathyrane diterpenene (2), and two known analaogues (3 and 4) have been isolated from Euphorbia prolifera. Their structures were elucidated as (12E,2S,3S,4R,5R,6S,9S,11S,15R)-3-butyryloxy-5,15-diacetoxy-6,17-epoxylathyra- 12-en-14-one (1), (12E,2S,3S,4R,5...

journal_title：Fitoterapia

authors： Xu J,Jin DQ,Song H,Guo Y,He Y

更新日期：2012-10-01 00:00:00

abstract：:Natural products have been investigated as potential candidates of novel therapeutics and play a crucial role in advanced medicinal drugs. Natural resources, including local medicinal plants (especially folk medicinal plants), animals, bacteria, and fungi have been used for more than a century, and are precious gifts ...

journal_title：Fitoterapia

authors： Wang X,Yamauchi K,Mitsunaga T

更新日期：2020-04-01 00:00:00

abstract：:The methanolic extract of the Zanthoxylum rhetsa Roxb. stem bark, given by oral route to mice at doses of 250 and 500 mg/kg, significantly reduced the abdominal contraction induced by acetic acid and the diarrhoeal episodes induced by castor oil in mice. ...

journal_title：Fitoterapia

authors： Rahman MT,Alimuzzaman M,Ahmad S,Chowdhury AA

更新日期：2002-07-01 00:00:00

abstract：:Antioxidant activity of the ethanol extract of Erigeron breviscapus (EEEB) were studied by using neuron oxidative injury model induced by superoxide radical. EEEB at the dose of 10-140 mug/ml reduced significantly the lipid peroxidation levels and lactic dehydrogenase (LDH) release from neuron exposed to superoxide ra...

journal_title：Fitoterapia

authors： Liu H,Yang X,Ren T,Feng Y,Xu H

更新日期：2005-12-01 00:00:00

abstract：:Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and three of them were diastereomers for each other. Compounds 1-7 were evaluated f...

journal_title：Fitoterapia

authors： Meng D,Li X,Han L,Zhang L,An W,Li X

更新日期：2014-01-01 00:00:00

abstract：:Two new alkaloids were isolated from the bark of Sarcomelicope megistophylla. Cyclomegistine B (1), a new quinolone alkaloid, that possesses a rare cyclobuta[b]quinoline ring system and sarcomejine B (2) which is a quinolone alkaloid with an unusual side chain. The structure of both compounds was elucidated on the bas...

journal_title：Fitoterapia

authors： Mitaku S,Fokialakis N,Magiatis P,Tillequin F

更新日期：2007-02-01 00:00:00

abstract：:Sardinian wild Euphorbia pithyusa, E. semiperfoliata, E. dendroides and E. characias seed oils were analyzed for their fatty acids, unsaponifiable and tocopherol content. Total tocopherol content showed a wide variability, ranging from 939 mg/kg in E. semiperfoliata seeds to its absence in E. characias. The results on...

journal_title：Fitoterapia

authors： Bruni R,Muzzoli M,Ballero M,Loi MC,Fantin G,Poli F,Sacchetti G

更新日期：2004-01-01 00:00:00

abstract：:The plants of genus Toona are well known for diverse limonoid secondary metabolites, while polyacetylenes are rarely found from Toona species. In this work, six new polyacetylenes toonasindiynes A-F (1-6) and six known analogues (7-12) were isolated from the root bark of Toona sinensis. Their structures and absolute c...

journal_title：Fitoterapia

authors： Xu WJ,Li JH,Zhou MM,Luo J,Jian KL,Tian XM,Xia YZ,Yang L,Luo J,Kong LY

更新日期：2020-10-01 00:00:00

abstract：:Five new benzylphenanthrenes, cremaphenanthrenes L-P (1-5) were isolated from the EtOAc-soluble extract of the tubers of Cremastra appendiculata. Their structures were elucidated based on the spectroscopic data and chemical methods. Compounds 1-5 were tested in vitro for their cytotoxic effects against colon (HCT-116)...

journal_title：Fitoterapia

authors： Liu L,Li J,Zeng KW,Jiang Y,Tu PF

更新日期：2015-06-01 00:00:00

abstract：:The antioxidant activity of Citrus paradisi (grapefruit) seeds glyceric extract dissolved in ethanol and in aqueous media was evaluated using three different methods: evaluation by DPPH assay, by 5-lipoxygenase assay and by luminol/xanthine/xanthine oxidase chemiluminescence assay. The total phenolic content was deter...

journal_title：Fitoterapia

authors： Giamperi L,Fraternale D,Bucchini A,Ricci D

更新日期：2004-03-01 00:00:00

abstract：:Four new sesquiterpene lactones, named artemargyinolides A-D (1-4), and seven known sesquiterpenoids (5-11) were isolated from Artemisia argyi. Their structures were elucidated based on the extensive analysis of spectroscopic data. The absolute configuration of 1 was assigned by X-ray crystallographic analysis. Compou...

journal_title：Fitoterapia

authors： Zhang LB,Lv JL

更新日期：2019-11-01 00:00:00

abstract：:The Goodeniaceae family contributes some of the more spectacular wildflowers found on the Australian continent. The bright and vibrant colours that characterise members of the family has attracted much horticultural interest. A number of species have traditionally been used for medicinal purposes by indigenous communi...

journal_title：Fitoterapia

authors： Ghisalberti EL

更新日期：2004-07-01 00:00:00

abstract：:Five new ursane-type triterpenoids, spicatusoids A-E (1, 3-6), and three known ones (2, 7, and 8), and a known oleanane-type triterpenoid (9) were isolated from the aerial parts of Clerodendranthus spicatus. Their structures were elucidated by spectroscopic methods. In particular, the structure of 3 including its abso...

journal_title：Fitoterapia

authors： Luo Y,Cheng LZ,Luo Q,Yan YM,Wang SM,Sun Q,Cheng YX

更新日期：2017-06-01 00:00:00

abstract：:Diplacone (1) and mimulone (2), two geranylated flavanones, have previously shown anti-inflammatory and antiradical activity in vitro. The present study aimed to evaluate their activity in vivo on a model of colitis induced in Wistar rats by an oral administration of dextran sulfate sodium (DSS). Diplacone (1) and mim...

journal_title：Fitoterapia

authors： Vochyánová Z,Bartošová L,Bujdáková V,Fictum P,Husník R,Suchý P,Šmejkal K,Hošek J

更新日期：2015-03-01 00:00:00

abstract：:Three novel xanthonolignoid C-glycosides, glomexanthones A-C, with a trans-dihydrobenzofuran on B ring and a 2-hydroxymethyl-5-hydroxyl-2-pentenoic acid moiety in the sugar chain were isolated from an ethanol extract of Polygala glomerata. Their structures and absolute configurations were characterized by extensive NM...

journal_title：Fitoterapia

authors： Li CJ,Yang JZ,Yu SS,Zhao CY,Peng Y,Wang XL,Zhang DM

更新日期：2014-03-01 00:00:00

abstract：:A screening was conducted with 26 plants collected in the Brazilian southeast region, to identify plant extracts with antibacterial properties against Aeromonas hydrophila, Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus. Initially, the agar diffusion method was employed. Then, those extracts prese...

journal_title：Fitoterapia

authors： Oliveira DF,Pereira AC,Figueiredo HC,Carvalho DA,Silva G,Nunes AS,Alves DS,Carvalho HW

更新日期：2007-02-01 00:00:00

abstract：:Chemical investigation of the cultured polyspore-derived mycobionts of a Pseudopyrenula subnudata lichen led to the isolation of two new compounds, subnudatones A and B (1 and 2), together with four known compounds, 1-(2-hydroxy-1,2,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)ethanone (3), libertalide C (4)...

journal_title：Fitoterapia

authors： Duong TH,Nguyen HH,Le TT,Tran TN,Sichaem J,Nguyen TT,Nguyen TP,Mai DT,Nguyen HH,Le HD

更新日期：2020-04-01 00:00:00

abstract：:A new sesquiterpene lactone, 7alpha,10alpha-epoxy-1alpha(H),5alpha(H)-guaia-3,11(13)-dien-8alpha,12-olide, was isolated from the leaves of Hedyosmum arborescens. The structure of this unusual 7,10-epoxy-guaianolide was determined by spectroscopic methods, particularly one- and two-dimensional 1H and 13C NMR. ...

journal_title：Fitoterapia

authors： Bercion S,Couppe de K Martin MA,Baltaze JP,Bourgeois P

更新日期：2005-12-01 00:00:00

abstract：:A new megastigmane sesquiterpene glucoside named chaihuxinoside A (1), and a new indole diglucoside named chaihuxinoside B (9) were isolated from the aerial parts of Bupleurum chinense DC. along with eight known compounds. Structures of two new compounds were elucidated by a combination of chemical and spectroscopic m...

journal_title：Fitoterapia

authors： Kuang H,Sun S,Yang B,Xia Y,Feng W

更新日期：2009-01-01 00:00:00

abstract：:Influenza poses a particular risk of severe outcomes in the elderly, the very young and those with underlying diseases. Tea polyphenols are the natural phenolic compounds in teas, and principally consist of catechins, proanthocyanidins, flavonols, and theaflavins, which antiviral activities have been reported recently...

journal_title：Fitoterapia

authors： Yang ZF,Bai LP,Huang WB,Li XZ,Zhao SS,Zhong NS,Jiang ZH

更新日期：2014-03-01 00:00:00

abstract：:The pharmacological active genus Thymus L. comprises over 200 species. Besides its traditional pharmacological use, thyme may reduce the risk of caries disease, however, there is very little respective literature. The pharmacological effects can be attributed to the secondary plant metabolites. The composition of the ...

journal_title：Fitoterapia

authors： Schött G,Liesegang S,Gaunitz F,Gleß A,Basche S,Hannig C,Speer K

更新日期：2017-09-01 00:00:00

abstract：:Investigation of the fruits of Khaya senegalensis resulted in the isolation of three new mexicanolide limonoids containing a rare conjugated diene lactone system named seneganolide A (1), 2-hydroxyseneganolide A (2) and 2-acetoxyseneganolide A (3). Two known limonoids, 3-deacetyl-7-deacetoxy-7-oxokhivorin (4) and meth...

journal_title：Fitoterapia

authors： Abdelgaleil SA,Iwagawa T,Doe M,Nakatani M

更新日期：2004-09-01 00:00:00

abstract：:Usually isolated from Garcinia (Clusiaceae) or Hypericum (Hypericaceae) species, some Polycyclic Polyprenylated AcylPhloroglucinols (PPAPs) have been recently reported as potential research tools for immunotherapy. Aiming at exploring the chemodiversity of PPAPs amongst Garcinia genus, a dereplication process suitable...

journal_title：Fitoterapia

authors： Bruguière A,Derbré S,Coste C,Le Bot M,Siegler B,Leong ST,Sulaiman SN,Awang K,Richomme P

更新日期：2018-11-01 00:00:00

abstract：:Three new clerodane type diterpenoids (2-4), together with one known analogues (1), were isolated from the tuberous roots of Tinospora sagittata (Oliv.) Gagnep. Compound 3 is an unusual clerodane diterpenoid with the carbonyl functionality at C-3, which represents the first example from this diterpenoid compounds clas...

journal_title：Fitoterapia

authors： Zhang G,Ma H,Hu S,Xu H,Yang B,Yang Q,Xue Y,Cheng L,Jiang J,Zhang J,Wang F,Zhang Y

更新日期：2016-04-01 00:00:00

abstract：:Three new mixed terpenoids, tricycloalternarenes (TCAs) F-H (1-3), together with ten known tricycloalternarenes (4-13), were isolated from the Czapek's culture of an endophytic fungus Ulocladium sp. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data...

journal_title：Fitoterapia

authors： Wang QX,Bao L,Yang XL,Guo H,Ren B,Guo LD,Song FH,Wang WZ,Liu HW,Zhang LX

更新日期：2013-03-01 00:00:00

abstract：:In the last 20 years, wine phenolic compounds have received increasing interest since several epidemiological studies have suggested associations between regular consumption of moderate amount of wine and prevention of certain chronic pathologies, such as neurodegenerative diseases. This study was aimed to investigate...

journal_title：Fitoterapia

authors： Giacoppo S,Galuppo M,Lombardo GE,Ulaszewska MM,Mattivi F,Bramanti P,Mazzon E,Navarra M

更新日期：2015-06-01 00:00:00

abstract：:A series of new Lycopodium alkaloids, namely 1-epi-malycorin A (1), 1-epi-17S-hydroxymalycorin A (2), 6α-hydroxyphlegmariurine A (3), 2S,4R-dihydroxyfawcettimine (4), and 16-hydroxylycodine (5), together with 24 known ones, have been isolated from the club moss Phlegmariurus henryi. The structures of the new compounds...

journal_title：Fitoterapia

authors： Liu YC,Su J,Wu XD,Zhang ZJ,Fan M,Zhu QF,He J,Li XN,Peng LY,Cheng X,Zhao QS

更新日期：2016-12-01 00:00:00

abstract：:The aqueous extract of Crinum giganteum given intraperitoneally at doses of 6.25, 12.5 and 25 mg/kg in rats prolonged the duration of pentobarbital sleeping time and in mice reduced spontaneous motor activity, decreased the exploratory activity and attenuated amphetamine-induced stereotype behavior. The intraperitonea...

journal_title：Fitoterapia

authors： Amos S,Binda L,Akah P,Wambebe C,Gamaniel K

更新日期：2003-02-01 00:00:00

abstract：:Fruit's decoctions of Passiflora edulis and P. foetida var. albiflora were evaluated for the inhibition of activity of gelatinase MMP-2 and MMP-9, two metallo-proteases involved in the tumour invasion, metastasis and angiogenesis. Both water extracts, at different concentrations, inhibited the enzymes. ...

journal_title：Fitoterapia

authors： Puricelli L,Dell'Aica I,Sartor L,Garbisa S,Caniato R

更新日期：2003-04-01 00:00:00