New ursane-type triterpenoids from Clerodendranthus spicatus.

abstract：:Ten new highly oxygenated lanostane triterpenoids, stereinones A-J (1-10), were isolated from the fruiting bodies of the basidiomycete Stereum sp. Compounds 3 and 4 are structurally characterized as intact lanostane-type triterpenoids containing unusual 1,2-diketone functionality at C-11 and C-12, while compound 10 is...

journal_title：Fitoterapia

authors： Yao JN,Chen L,Chen HP,Zhao ZZ,Zhang SB,Huang Y,Tang Y,Isaka M,Li ZH,Feng T,Liu JK

更新日期：2018-03-01 00:00:00

abstract：:In the present work, we reported the triterpenoids isolated from n-butanol fraction of Kadsura heteroclita which is a Tujia ethnomedicine with trivial name "Xuetong". This effort resulted in the isolation of six unpresented triterpenoids xuetongsu A-F (1-6), along with five known triterpenoids (7-11). The structures o...

journal_title：Fitoterapia

authors： Cao L,Li B,Shehla N,Gong LM,Jian YQ,Peng CY,Sheng WB,Liu LP,Cai X,Man RY,Liao DF,Zhu XQ,Choudhary MI,Rahman AU,Wang W

更新日期：2020-01-01 00:00:00

abstract：:The antimicrobial and cytotoxic activities of six lignans isolated from the core and bark acetone extracts of Hibiscus cannabinus have been investigated. Two compounds (2 and 3) showed strong cytotoxic activity against HeLa, Hep-2 and A-549 cell lines while compound 5 showed moderate activity on HeLa cells when they w...

journal_title：Fitoterapia

authors： Moujir L,Seca AM,Silva AM,López MR,Padilla N,Cavaleiro JA,Neto CP

更新日期：2007-07-01 00:00:00

abstract：:Investigation of the fruits of Khaya senegalensis resulted in the isolation of three new mexicanolide limonoids containing a rare conjugated diene lactone system named seneganolide A (1), 2-hydroxyseneganolide A (2) and 2-acetoxyseneganolide A (3). Two known limonoids, 3-deacetyl-7-deacetoxy-7-oxokhivorin (4) and meth...

journal_title：Fitoterapia

authors： Abdelgaleil SA,Iwagawa T,Doe M,Nakatani M

更新日期：2004-09-01 00:00:00

abstract：:A simple, sensitive and accurate liquid chromatographic method with photodiode-array detection was developed for determination of dehydroevodiamine with detection wavelength at 368 nm and column temperature at 30 degrees C. The separation was carried out on an Agilent Zorbax SB-C(18) column (250 mm x 4.6 mm, 5 microm)...

journal_title：Fitoterapia

authors： Zhao Y,Zhou X,Chen HG,Gong XJ,Cai ZW,Zhou CY

更新日期：2009-10-01 00:00:00

abstract：:A phytochemical investigation on the leaves of Tripterygium wilfordii Hook. F. was conducted, leading to the isolation of five undescribed dihydro-β-agarofuran sesquiterpenoids (1-5) and one known analogue (6). Their structures were determined by comprehensive spectroscopic analyses. The absolute configurations of the...

journal_title：Fitoterapia

authors： Zhao P,Lin B,Hou ZL,Zhou L,He QJ,Yao GD,Huang XX,Song SJ

更新日期：2020-04-01 00:00:00

abstract：:Four new taraxerane triterpenoids, 1β,3β-dihydroxy-11α,12α-oxidotaraxerane (1), 28-hydroxy-11α,12α-oxidotaraxerane-3-one (2), 3β-hydroxy-11α,12α-oxidotaraxerane-28-al (3), and 3-O-acetyl-11α,12α-oxidotaraxerane-28-al (4), together with three known compounds 3β-hydroxy-11α,12α-oxidotaraxerane (5), 3β,28-dihydroxy-11α,1...

journal_title：Fitoterapia

authors： Hu J,Shi X,Chen J,Huang H,Zhao C

更新日期：2012-01-01 00:00:00

abstract：:The essential oil from the aerial parts of Seseli annuum, wild-growing in Serbia, was obtained by hydrodistillation and analyzed using GC and GC/MS. A total of 43 components were identified representing 96.5% of S. annuum oil. The most abundant compounds were germacrene D (29.8%), sabinene (10.3%), beta-ocimene Z (9.8...

journal_title：Fitoterapia

authors： Milosavljević S,Tesević V,Vucković I,Jadranin M,Vajs V,Soković M,Janaćković P,Jovanović A

更新日期：2007-06-01 00:00:00

abstract：:Sarcandracoumarin (1), the first coumarin having a 1-phenylethyl substituent at the C-3 position, was isolated along with eleven known phenolic compounds from the water extract of Sarcandra glabra. Its structure was elucidated on the basis of spectroscopic data. Compound 1 exhibited moderate or weak cytotoxicity again...

journal_title：Fitoterapia

authors： Feng S,Xu L,Wu M,Hao J,Qiu SX,Wei X

更新日期：2010-09-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is highly prevalent among global populations, with an estimated number of infected patients being 170 million. Approximately 70-80% of patients acutely infected with HCV will progress to chronic liver disease, such as liver cirrhosis and hepatocellular carcinoma, which is a substantia...

journal_title：Fitoterapia

authors： Wahyuni TS,Widyawaruyanti A,Lusida MI,Fuad A,Soetjipto,Fuchino H,Kawahara N,Hayashi Y,Aoki C,Hotta H

更新日期：2014-12-01 00:00:00

abstract：:The antioxidant activity of Agrimonia eupatoria (Agrimony) and Agrimonia procera (Fragrant agrimony) extracts was assessed by measuring in DPPH radical scavenging and ABTS(+) radical decolourisation reaction systems. Radical scavenging capacity of agrimony extracts varied in a wide range (9.1-97.5% in DPPH reaction an...

journal_title：Fitoterapia

authors： Venskutonis PR,Skemaite M,Ragazinskiene O

更新日期：2007-02-01 00:00:00

abstract：:A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 ...

journal_title：Fitoterapia

authors： Li L,Deng X,Zhang L,Shu P,Qin M

更新日期：2011-06-01 00:00:00

abstract：:Besides the unquestionable positive effects of solar exposure for human health, UV rays have been widely investigated for toxicology aspects related to excessive UVB and UVA doses, which involve sunburns, skin aging, DNA skin damage and tumorigenesis. At present, synthetic and mineral sunscreens are used to protect ag...

journal_title：Fitoterapia

authors： Radice M,Manfredini S,Ziosi P,Dissette V,Buso P,Fallacara A,Vertuani S

更新日期：2016-10-01 00:00:00

abstract：:Three new caged polyprenylated benzophenone derivatives named burlemarxiones D-F (1-3) were isolated from the hexane extract of Clusia burle-marxii trunks. Burlemarxione D (1) contains the tetracyclo[8.3.1.03,11.05,10]tetradecane core skeleton also observed for burlemarxione A, its probable immediate precursor. Howeve...

journal_title：Fitoterapia

authors： Ferraz CG,Ribeiro PR,Mendonça R,Silveira ER,Cruz FG

更新日期：2020-10-16 00:00:00

abstract：:Since the extract from berries of Aronia melanocarpa presents antioxidative properties in plasma and in blood platelets, not only from healthy group, but also from patients with benign breast diseases and in patients with invasive breast cancer before surgery, the aim of our present study was to evaluate the oxidative...

journal_title：Fitoterapia

authors： Kedzierska M,Olas B,Wachowicz B,Glowacki R,Bald E,Czernek U,Szydłowska-Pazera K,Potemski P,Piekarski J,Jeziorski A

更新日期：2012-03-01 00:00:00

abstract：:The Goodeniaceae family contributes some of the more spectacular wildflowers found on the Australian continent. The bright and vibrant colours that characterise members of the family has attracted much horticultural interest. A number of species have traditionally been used for medicinal purposes by indigenous communi...

journal_title：Fitoterapia

authors： Ghisalberti EL

更新日期：2004-07-01 00:00:00

abstract：:Two new triterpenoid estersaponins (1, 2) were isolated from the leaves of Pittosporum tobira 'Variegata' (Thunb.) W. T. Aiton, along with one known saponin (3) and one known flavonoid glycoside (4). Their structures were established by different spectroscopic methods including 1D and 2D NMR, UV, as well as ESI-MS ana...

journal_title：Fitoterapia

authors： El Dib RA,Eskander J,Mohamed MA,Mohammed NM

更新日期：2015-10-01 00:00:00

abstract：:Soluble proteins from the latex of Calotropis procera (LP) were investigated in vitro and in vivo for digestibility as the latex has previously been shown to produce considerable toxic effects on animals. The latex is also an important biologically active compound that displays antiinflammatory and antidiarrhea proper...

journal_title：Fitoterapia

authors： Ramos MV,Aguiar VC,da Silva Xavier AA,Lima MW,Bandeira GP,Etchells JP,Nogueira NA,Alencar NM

更新日期：2006-06-01 00:00:00

abstract：:The crude extracts of the leaves of Dodonaea viscosa and Rumex nervosus as well as of the root of Rumex abyssinicus were tested for anti-microbial and anti-inflammatory activities. It was observed that the three plants possess antibacterial activity against Streptococcus pyogenes and Staphylococcus aureus and strong a...

journal_title：Fitoterapia

authors： Getie M,Gebre-Mariam T,Rietz R,Höhne C,Huschka C,Schmidtke M,Abate A,Neubert RH

更新日期：2003-02-01 00:00:00

abstract：:The furanocoumarin imperatorin has been reported to have hypotensive effect, and we have investigated its activity on myocardial hypertrophy. Imperatorin displayed similar chromatographic retention peak to verapamil in the model of cardiac muscle/cell membrane chromatography, and could reduce in a concentration-depend...

journal_title：Fitoterapia

authors： Zhang Y,Cao Y,Zhan Y,Duan H,He L

更新日期：2010-12-01 00:00:00

abstract：:This manuscript reports on the first CE-method suitable for analyzing twelve pharmacologically relevant compounds (flavonoids, caffeic acids and leontopodic acid) in the aerial parts of Leontopodium alpinum. By using a 60mM borax buffer containing 25mM SDS and 35% acetonitrile the analytes could be well resolved in 25...

journal_title：Fitoterapia

authors： Ganzera M,Greifeneder V,Schwaiger S,Stuppner H

更新日期：2012-12-01 00:00:00

abstract：:Aqueous extract of Pteris multifida showed scavenging activities on DPPH, hydroxyl radicals and reducing power. ...

journal_title：Fitoterapia

authors： Wang TC,Ti MC,Lo SC,Yang CC

更新日期：2007-04-01 00:00:00

abstract：:Phytochemical investigation of Tephrosia vogelii seedpods led to the isolation of twelve compounds: vogelisoflavone A (1), vogelisoflavone B (2), isopongaflavone (3), onogenin, luteolin, 4',7-dihydroxy-3'-methoxyflavanone, trans-p-hydroxycinnamic acid, tephrosin, 2-methoxygliricidol, dehydrorotenone, 6a,12a-dehydro-α-...

journal_title：Fitoterapia

authors： Owor RO,Derese S,Bedane KG,Zühlke S,Ndakala A,Spiteller M

更新日期：2020-10-01 00:00:00

abstract：:Anti-nociceptive and anti-oedematogenic effects of the aqueous extract from the leaves of Erythrina velutina were tested through experimental models of nociception in mice and paw oedema induced by carrageenin in rats. The extract (300 and 600 mg/kg) did not change the carrageenin-induced paw oedema. In the hot plate ...

journal_title：Fitoterapia

authors： Marchioro M,Blank Mde F,Mourão RH,Antoniolli AR

更新日期：2005-12-01 00:00:00

abstract：:Cajaninstilbene acid (CSA), a bioactive constituent isolated from pigeon pea leaves, exhibited neuroprotective activities in previous studies. The present study aims to evaluate the antidepressant effects of CSA by using behavioral despair models of tail suspension test (TST) and forced swimming test (FST), and a chro...

journal_title：Fitoterapia

authors： Zhang MD,Tao X,Pan RL,Wang LS,Li CC,Zhou YF,Liao YH,Chen SG,Chang Q,Liu XM

更新日期：2020-03-01 00:00:00

abstract：:Centella asiatica (L.) Urban is a medicinal herb traditionally used in Asiatic countries for its multiple therapeutic properties, essentially due to its accumulation of specific pentacylic triterpenoid saponins, mainly asiaticoside and madecassoside and the corresponding sapogenins. This review summarizes the updated ...

journal_title：Fitoterapia

authors： Azerad R

更新日期：2016-10-01 00:00:00

abstract：:The isolation of five flavonol glycosides (1-5) from the flowers of Aconitum vulparia is reported, together with the 1H- and 13C-NMR spectral data in CD(3)OD of compound 3 and 5. ...

journal_title：Fitoterapia

authors： Fico G,Braca A,Morelli I,Tomè F

更新日期：2003-06-01 00:00:00

abstract：:Seven new lignans, cleistonkinins A- E (1-5), cleistonkisides A and B (6-7) were isolated from the fruits of Cleistanthus tonkinensis (Euphorbiaceae), together with five known aryltetralin lignans, cleisindoside B (8), cleistantoxin (9), cleisindoside D (10), neocleistantoxin (11) and polygamain (12). Their structures...

journal_title：Fitoterapia

authors： Nguyen LH,Vu VN,Phi Thi D,Tran VH,Litaudon M,Roussi F,Nguyen VH,Chau VM,Doan Thi Mai H,Pham VC

更新日期：2020-01-01 00:00:00

abstract：:The root of Coptis chinensis Franch. (COCH) is regularly used for medicinal purposes, and has been prescribed alone or in combination with other traditional herbs for the treatment of diabetes. To investigate the effects of COCH on glucose utilization by skeletal muscles, we prepared an ethanol extract of COCH root (C...

journal_title：Fitoterapia

authors： Yang TC,Chao HF,Shi LS,Chang TC,Lin HC,Chang WL

更新日期：2014-03-01 00:00:00

abstract：:Two new guaiane-type sesquiterpenoids containing an interesting epoxy unit, daucuside (1) and daucusol (2) were isolated from the fruits of Daucus carota L. Their chemical structures were elucidated on the basis of MS, NMR spectroscopic analyses coupled with chemical degradation and they were also evaluated for the cy...

journal_title：Fitoterapia

authors： Fu HW,Zhang L,Yi T,Feng YL,Tian JK

更新日期：2010-07-01 00:00:00