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Cytotoxic activity of lignans from Hibiscus cannabinus.

Abstract：

:The antimicrobial and cytotoxic activities of six lignans isolated from the core and bark acetone extracts of Hibiscus cannabinus have been investigated. Two compounds (2 and 3) showed strong cytotoxic activity against HeLa, Hep-2 and A-549 cell lines while compound 5 showed moderate activity on HeLa cells when they were in advanced stage of cellular division. The compounds did not exhibit antimicrobial activity.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Moujir L,Seca AM,Silva AM,López MR,Padilla N,Cavaleiro JA,Neto CP

doi

10.1016/j.fitote.2007.03.010

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

385-7

issue

5

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(07)00076-7

journal_volume

78

pub_type

杂志文章

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