Sesquiterpene coumarins from seeds of Ferula sinkiangensis.

Abstract:

:A new sesquiterpene coumarin with a novel sesquiterpene carbon framework, Sinkiangenorin D, and ten known sesquiterpene coumarins were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds, including the relative stereochemistry, were elucidated on the basis of spectroscopic data. All of the isolated compounds were tested against the AGS, HeLa, and K562 human cancer cell lines and showed cytotoxic activities with 50% inhibitory concentration values between 12.7 and 226.6 μM.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Li G,Li X,Cao L,Zhang L,Shen L,Zhu J,Wang J,Si J

doi

10.1016/j.fitote.2015.03.022

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

222-6

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(15)00076-3

journal_volume

103

pub_type

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