Abstract:
:A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 and 4 showed strong lymphocyte proliferation inhibitory activity with an IC(50) value of 1.04-2.76 μM, and the low cytotoxicity with the CC(50) value of 71.01 and 56.36 μM, respectively.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Li L,Deng X,Zhang L,Shu P,Qin Mdoi
10.1016/j.fitote.2011.01.019subject
Has Abstractpub_date
2011-06-01 00:00:00pages
615-9issue
4eissn
0367-326Xissn
1873-6971pii
S0367-326X(11)00040-2journal_volume
82pub_type
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