Abstract:
:Five novel globoscinic acid derivatives, aspergilates A-E (1-5) have been isolated from endophytic fungus Aspergillus sp. derived from Paeonia ostii. The structures of aspergilates A-E were determined by in-depth analyses of NMR spectra, HRESIMS and CD experiments. The absolute configurations of compounds 2-5 were determined by the ECD calculations based on quantum chemistry. Cytotoxic activities against five selected tested tumor cell lines of 1-5 were evaluated.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Wang JT,Zhang PL,Liu JS,Wang GK,Xu FQ,Chen L,Yu Y,Wang Gdoi
10.1016/j.fitote.2018.10.027subject
Has Abstractpub_date
2018-11-01 00:00:00pages
204-208eissn
0367-326Xissn
1873-6971pii
S0367-326X(18)31680-0journal_volume
131pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract::Four new lathyrane-type diterpenoids (1-4) and a novel macrocyclic diterpenoid (5) featuring a 5/7/7/4-fused ring system, together with seventeen known ones (6-22), were isolated from the seeds of Euphorbia lathyris. Their structures were elucidated by extensive spectroscopic analyses and single crystal X-ray crystall...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2021.104834
更新日期:2021-01-26 00:00:00
abstract::Combinations of thyme, cowslip and liquorice roots are often used in the treatment of upper respiratory tract infections. Therefore the volatile fraction of herbal teas prepared from thyme (Thymus vulgaris) and the effect of combining with cowslip (Primula veris/P. elatior) and liquorice roots (Glycyrrhiza glabra) on ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.05.006
更新日期:2011-09-01 00:00:00
abstract::A sensitive and specific HPLC method was developed to analyze baicalin in rat plasma. The author had compared the pharmacokinetics of baicalin after oral administration of HLJDT decoction or pure baicalin in MCAO and sham-operated rats. All the rats were divided into two groups, MCAO and sham-operated rats. Each group...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2010.01.004
更新日期:2010-09-01 00:00:00
abstract::Two new xanthones: mangostanaxanthones I (3) and II (5) were isolated from the pericarp of Garcinia mangostana, along with four known xanthones: 9-hydroxycalabaxanthone (1), parvifolixanthone C (2), α-mangostin (4), and rubraxanthone (6). Their structures were elucidated on the basis of IR, UV, 1D, 2D NMR, and MS spec...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.08.014
更新日期:2014-10-01 00:00:00
abstract::The Goodeniaceae family contributes some of the more spectacular wildflowers found on the Australian continent. The bright and vibrant colours that characterise members of the family has attracted much horticultural interest. A number of species have traditionally been used for medicinal purposes by indigenous communi...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2004.01.018
更新日期:2004-07-01 00:00:00
abstract::Caesalpinone A (1), a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, along with ten known sesquiterpenoids (2-11) were isolated from the pods of Caesalpinia spinosa Kuntze (Tara). The structure of caesalpinone A was elucidated based on its 1D and 2D NMR spectra. The absolute configurati...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.06.012
更新日期:2016-07-01 00:00:00
abstract::Methanol extract of the stem bark of Hymenodictyon parvifolium was tested for its antifungal and antibacterial activity. The extract was found to have inhibitory effect against all the pathogens tested. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(02)00176-4
更新日期:2002-10-01 00:00:00
abstract::The isolation of a new flavan, 5,7,4'-trihydroxy-8-ethoxycarbonylflavan (1), from the root of Daphne odora var. atrocaulis is reported. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2004.09.014
更新日期:2004-12-01 00:00:00
abstract::A new guanidine alkaloid, millaurine A (1), was isolated from the methanol extract of the seeds of Millettia laurentii. The structure of the new compound was elucidated on the basis of spectral analysis. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2006.11.018
更新日期:2007-04-01 00:00:00
abstract::Although the nature-identical chemical compounds are cheaper, they not always repeat biological activity of plant origin natural chemical compounds, often react allergies and resistance of microorganisms. The aim of this study was to investigate effects of Juniperus communis origin α-pinene with different enantiomeric...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.04.013
更新日期:2018-06-01 00:00:00
abstract::Eight new flavonoids daemoflavans A-H, including two dimeric proanthocyanidins (1 and 2), four flavans (3-6), two 2-arylbenzofurans (7 and 8), along with nine known compounds (9-17), were isolated from the fruit of Daemonorops draco. Their structures, including the absolute configurations, were elucidated by extensive...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2020.104549
更新日期:2020-06-01 00:00:00
abstract::A simple, sensitive and accurate liquid chromatographic method with photodiode-array detection was developed for determination of dehydroevodiamine with detection wavelength at 368 nm and column temperature at 30 degrees C. The separation was carried out on an Agilent Zorbax SB-C(18) column (250 mm x 4.6 mm, 5 microm)...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2009.05.017
更新日期:2009-10-01 00:00:00
abstract::Two ethanolic propolis extracts (EPE) with and without the caffeic acid phenethyl ester (CAPE), CAPE and galangin (major components of propolis) were investigated for anti-inflammatory activity in rats using carrageenin foot oedema, carrageenin pleurisy and adjuvant arthritis. In our experiments, EPE with CAPE and CAP...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(02)00191-0
更新日期:2002-11-01 00:00:00
abstract::Silymarin, a standardised extract of Silybum marianum (milk thistle), comprises mainly of silybin, with dehydrosilybin (DHSB), quercetin, taxifolin, silychristin and a number of other compounds which are known to possess a range of salutary effects. Indeed, there is evidence for their role in reducing tumour growth, p...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2014.05.016
更新日期:2014-09-01 00:00:00
abstract::Five new sesquiterpenoids, including two linderanes (1-2) and three eudesmanes (3-5) were isolated from the seeds of Sarcandra glabra. Their structures and relative configurations were established by spectroscopic data analysis. 1 was a rare linderane derivative having an 18-membered triester ring which is a common ch...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.03.020
更新日期:2016-06-01 00:00:00
abstract::Four new eburnamine-aspidospermine type bisindole alkaloids, namely, mekongenines C-F (1-4), along with 27 known indole alkaloids were isolated from the twigs and leaves of Bousigonia mekongensis. Their structures with the absolute configurations were elucidated by spectroscopic methods and ECD analyses. All new compo...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.07.008
更新日期:2014-10-01 00:00:00
abstract::The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml a...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2005.04.019
更新日期:2005-09-01 00:00:00
abstract::The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.12.017
更新日期:2014-03-01 00:00:00
abstract::Five new cadinene-type sesquiterpenes, hibiscusterpenes I-V (1-5), and six known compounds (6-11) have been isolated from the methanol extract of the stems and the twigs of Hibiscus tiliaceus. The structures of the new compounds were elucidated based on chemical and spectroscopic evidence. The absolute stereochemistry...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2020.104524
更新日期:2020-04-01 00:00:00
abstract::Two novel eremophylane acetophenone conjugates, colletotricholides A (1) and B (2), were isolated from the solid fermentation cultures of an endophytic fungus Colletotrichum gloeosporioides XL1200 isolated from the aerial parts of Salvia miltiorrhiza. The chemical structures of 1-2 were characterized by extensive spec...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2020.104474
更新日期:2020-03-01 00:00:00
abstract::Two new benzofuran derivatives, 2-(4'-hydroxybenzyl)-5,6-methylenedioxy-benzofuran (1) and 2-(4'-hydroxybenzoyl)-5,6-methylenedioxy-benzofuran (2), along with 8 known compounds were isolated from 60% EtOH extract of the fibrous roots of Liriope spicata var. prolifera. Their structures were elucidated on the basis of e...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2010.09.002
更新日期:2011-03-01 00:00:00
abstract::Four new aristolochic acid derivatives aristchamic A (1), aristchamic B (2), aristochamic C (3a), aristchamic D (3b) and one new aristolactam aristolactam-CV (4), together with 10 known compounds (5-14), were isolated from the rhizomes of Aristolochia championii. Their structures were assigned by detailed analysis of ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.01.006
更新日期:2017-04-01 00:00:00
abstract::The present study was designed to verify whether frutalin (FTL) affords gastroprotection against the ethanol-induced gastric damage and to examine the underlying mechanism(s). Gastric damage was induced by intragastric administration of 0.2 ml of ethanol (96%). Mice in groups were pretreated with FTL (0.25, 0.5 and 1 ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.01.005
更新日期:2012-04-01 00:00:00
abstract::The methanol extract of Leucas aspera flowers, its fractions, the alkaloidal residue and the expressed flower juice, tested for antimicrobial activity, showed good antibacterial activity for methanol extract and methanol fraction with maximum activity for the alkaloidal residue. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2005.08.009
更新日期:2005-12-01 00:00:00
abstract::Callus and differentiated shoots initiated from Solanum tuberosum L. on MS media containing BA, IAA, and Kin. Glycoalkaloids are produced in callus and shoots in concentrations higher than original tubers using HPLC. Callus methanolic extract had promising anticancer activity with low IC(50) values against human carci...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2010.03.001
更新日期:2010-09-01 00:00:00
abstract::The methanol extract and four triterpenoids isolated from the seeds of Caesalpinia bonducella showed a wide range of inhibiting activity against both gram-positive and gram-negative bacteria. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(01)00292-1
更新日期:2001-11-01 00:00:00
abstract::A new flavone, 4'-hydroxy-6,7-methylenedioxy-3-methoxyflavone 1, and two other nucleosides, ribavirin 2 and adenosine 3, were isolated from the leaves of Dulacia egleri. The nucleosides were identified by spectroscopic techniques (1D, 2D-NMR) while the structure of the flavonoid was established by 1D, 2D-NMR analysis,...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.08.005
更新日期:2019-01-01 00:00:00
abstract::Phytochemical study on rhizomes of Cimicifuga dahurica resulted in the isolation of nine new neolignan and phenylpropanoid glycosides, cimicifugasides A-E (1, 2, 7-9), cimicifugamides B-D (3-5), shomaside G (6) along with four known compounds (10-13). Their structures were identified by extensive spectroscopic analyse...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.03.023
更新日期:2019-04-01 00:00:00
abstract::Thirty four terpenoids, including two new cadinane-type sesquiterpenoids containing conjugated aromatic-ketone moieties, curcujinone A (1) and curcujinone B (2), were isolated from 95% ethanol extract of the root tubers of Curcuma wenyujin. Their structures were determined by spectroscopic methods, especially 2D NMR a...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.06.011
更新日期:2017-09-01 00:00:00
abstract::A new altersolanol derivative, 4-dehydroxyaltersolanol A (9), along with two known sesquiterpenoids, (S)-7'-hydroxyabscisic acid (7) and (S)-abscisic acid (8) were obtained from the endophytic fungus, Nigrospora oryzae, isolated from leaves of Combretum dolichopetalum. The host plant yielded six known compounds includ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.06.018
更新日期:2015-09-01 00:00:00