A new flavan from Daphne odora var. atrocaulis.

abstract：:Investigation of the bioactive secondary metabolites of the marine actinomycetes Rubrobacter radiotolerans led to the isolation and characterization of two naturally rare dimeric indole derivatives (1 and 2). The structures of these new compounds were elucidated by spectroscopic data interpretation, and the absolute c...

journal_title：Fitoterapia

authors： Li JL,Huang L,Liu J,Song Y,Gao J,Jung JH,Liu Y,Chen G

更新日期：2015-04-01 00:00:00

abstract：:Fourteen pregnane-type steroidal alkaloids were isolated from the ethanolic extracts of whole Sarcococca hookeriana var. digyna plants. Their structures were elucidated on the basis of spectral data. Three of them were identified as new steroidal alkaloids: (S)-20-(N,N-dimethylamino)-16α,17α-epoxy-3β-methoxy-pregn-5-e...

journal_title：Fitoterapia

authors： Zhang PZ,Wang F,Yang LJ,Zhang GL

更新日期：2013-09-01 00:00:00

abstract：:Five new aromatic compounds, designed as lucidumins A-D (1-4) and lucidimine E (9), along with seven known aromatic compounds (5-8, 10-12) were isolated from Ganoderma lucidum. Their structures were determined by spectroscopic method. Bioactive evaluation showed that compounds 2-4 and 6-10 displayed remarkable neuropr...

journal_title：Fitoterapia

authors： Lu SY,Peng XR,Dong JR,Yan H,Kong QH,Shi QQ,Li DS,Zhou L,Li ZR,Qiu MH

更新日期：2019-04-01 00:00:00

abstract：:A series of 33 curcumin analogues was synthesized and tested on TRPA1, TRPM8, and TRPV1 channels. Twenty of them acted as good modulators of TRPA1 channels. None was able to significantly activate TRPM8 channels, while curcumin itself and six curcuminoids belonging to the 1,3-dicarbonyl and acyclic series behaved as '...

journal_title：Fitoterapia

authors： Nalli M,Ortar G,Schiano Moriello A,Di Marzo V,De Petrocellis L

更新日期：2017-10-01 00:00:00

abstract：:A new sesquiterpene coumarin with a novel sesquiterpene carbon framework, Sinkiangenorin D, and ten known sesquiterpene coumarins were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds, including the relative stereochemistry, were elucidated on the basis of spectroscopic data. All of t...

journal_title：Fitoterapia

authors： Li G,Li X,Cao L,Zhang L,Shen L,Zhu J,Wang J,Si J

更新日期：2015-06-01 00:00:00

abstract：:The pharmacological active genus Thymus L. comprises over 200 species. Besides its traditional pharmacological use, thyme may reduce the risk of caries disease, however, there is very little respective literature. The pharmacological effects can be attributed to the secondary plant metabolites. The composition of the ...

journal_title：Fitoterapia

authors： Schött G,Liesegang S,Gaunitz F,Gleß A,Basche S,Hannig C,Speer K

更新日期：2017-09-01 00:00:00

abstract：:Ethanolic extract of Rungia repens aerials parts (300 and 600 mg/kg p.o) showed diuretic activity in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. ...

journal_title：Fitoterapia

authors： Basu SK,Arivukkarasu R

更新日期：2006-02-01 00:00:00

abstract：:A new cyclopeptide, pulvpeptin A (1), two pairs of norlignan lignanosides, tamariscinosides G and H (2, 3), together with five known compounds (4-8) were isolated from Selaginella pulvinata. The structures were elucidated by spectroscopic data and chemical degradation. The activity of tamariscinoside G (2) was evaluat...

journal_title：Fitoterapia

authors： Lv H,Li Y,Zhu M,Luo M,Qi J,Yu Z,Zhang H,Guo Y,Tong S,Li H,Yan J

更新日期：2020-06-01 00:00:00

abstract：:Curcuminoids possess powerful antioxidant activity as demonstrated in many chemical in vitro tests and in several in vivo trials. Nevertheless, the mechanism of this activity is not completely elucidated and studies on the in vivo antioxidant effects are still needed. Metabolomics may be used as an attractive approach...

journal_title：Fitoterapia

authors： Dall'Acqua S,Stocchero M,Boschiero I,Schiavon M,Golob S,Uddin J,Voinovich D,Mammi S,Schievano E

更新日期：2016-03-01 00:00:00

abstract：:The antituberculosis activity of 14 natural azorellane and mulinane diterpenoids isolated from Azorella compacta, Azorella madreporica, Mulinum crassifolium, and Laretia acaulis, together with eight semisynthetic derivatives, was evaluated against two Mycobacterium tuberculosis strains. The natural azorellanes azorell...

journal_title：Fitoterapia

authors： Molina-Salinas GM,Bórquez J,Ardiles A,Said-Fernández S,Loyola LA,San-Martín A,González-Collado I,Peña-Rodríguez LM

更新日期：2010-01-01 00:00:00

abstract：:The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...

journal_title：Fitoterapia

authors： Chen TL,Zhang YB,Xu W,Kang TG,Yang XW

更新日期：2014-03-01 00:00:00

abstract：:Rapid micropropagation of Nepeta rtanjensis, N. sibirica and N. nervosa was performed. Qualitative and quantitative nepetalactone content in methanol extracts of in vitro grown plants was analysed by reverse-phase HPLC coupled with UV and MS detection. Only trans,cis-nepetalactone was detected in shoots of N. rtanjens...

journal_title：Fitoterapia

authors： Nestorović J,Misić D,Siler B,Soković M,Glamoclija J,Cirić A,Maksimović V,Grubisić D

更新日期：2010-09-01 00:00:00

abstract：:Reinvestigation of Onopordon ambiguum extract afforded a new eudesmane derivative 1, in addition to the known elemanoid derivative 2. The structures of both compounds were determined by spectroscopic techniques, including 1H-, 13C-NMR, DEPT, 1H-1H and 1H-13C COSY analysis. ...

journal_title：Fitoterapia

authors： El-Moghazy SA,Ahmed AA,Abdel-Ghani HF,El-Shanawany MA

更新日期：2002-02-01 00:00:00

abstract：:The ethanolic extracts of Lawsonia inermis leaves, Holarrhena antidysenterica bark, Swertia chirata whole plant and Mangifera indica bark were tested (in-vitro) for alpha-glucosidase inhibitory activity. M. indica extract was found to be the most potent, with an IC(50) value of 314 microg/ml. ...

journal_title：Fitoterapia

authors： Prashanth D,Amit A,Samiulla DS,Asha MK,Padmaja R

更新日期：2001-08-01 00:00:00

abstract：:Seven new lignan glycosides (1-3, 8-10, and 14) and 17 known compounds were isolated from the branches of Alangium kurzii Craib var. laxifolium. Their structures were established by spectroscopic analysis and circular dichroism (CD) and X-ray analysis. The isolated compounds were evaluated for their antibacterial acti...

journal_title：Fitoterapia

authors： Ren J,Xie YG,Huang YY,Zhu SL,Yan SK,Jin HZ,Zhang WD

更新日期：2017-09-01 00:00:00

abstract：:The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the laboratory. The photoprotective effect of substances against UV-B induced cellular ...

journal_title：Fitoterapia

authors： Avila Acevedo JG,Castañeda CM,Benitez FJ,Durán DA,Barroso VR,Martínez CG,Muñoz LJ,Martínez CA,Romo de Vivar A

更新日期：2005-06-01 00:00:00

abstract：:The flavonoid fraction of Tephrosia purpurea (FFTP) was studied for its effect on cellular and humoral functions and on macrophage phagocytosis in mice. Oral administration of FFTP (10-40 mg/kg) significantly inhibited sheep red blood cells (SRBC)-induced delayed-type hypersensitivity reactions. It also produced a sig...

journal_title：Fitoterapia

authors： Damre AS,Gokhale AB,Phadke AS,Kulkarni KR,Saraf MN

更新日期：2003-04-01 00:00:00

abstract：:Four new aristolochic acid derivatives aristchamic A (1), aristchamic B (2), aristochamic C (3a), aristchamic D (3b) and one new aristolactam aristolactam-CV (4), together with 10 known compounds (5-14), were isolated from the rhizomes of Aristolochia championii. Their structures were assigned by detailed analysis of ...

journal_title：Fitoterapia

authors： Wang X,Shi GR,Liu YF,Li L,Chen RY,Yu DQ

更新日期：2017-04-01 00:00:00

abstract：:Tunicyclin L (1), cyclo (L-Pro1-Gly-L-Phe1-L-Ile-L-Pro2-L-Phe2 -L-Thr-L-Val), and 11 known compounds, including one cyclic peptide (2), eight carboline alkaloids (3 -10), one lignan (11) and one flavone (12) were isolated from the roots of Psammosilene tunicoides. Their structures were elucidated on the basis of exten...

journal_title：Fitoterapia

authors： Hou Y,Wang M,Sun C,Peng C,Zhang Y,Li X

更新日期：2020-09-01 00:00:00

abstract：:Four meroterpenoids, applanatumols F (1), H (3), I (2), and lingzhiol (4) were isolated from the 95% EtOH extract of the fruiting bodies of Ganoderma sinense. Their structures were established on the basis of NMR spectroscopic analyses, optical rotatory dispersion data, ECD spectra, and X-ray crystallography. Compound...

journal_title：Fitoterapia

authors： Gao S,Zhang P,Zhang C,Bao F,Li H,Chen L

更新日期：2018-11-01 00:00:00

abstract：:The methanol extract of Leucas aspera flowers, its fractions, the alkaloidal residue and the expressed flower juice, tested for antimicrobial activity, showed good antibacterial activity for methanol extract and methanol fraction with maximum activity for the alkaloidal residue. ...

journal_title：Fitoterapia

authors： Mangathayaru K,Lakshmikant J,Shyam Sundar N,Swapna R,Grace XF,Vasantha J

更新日期：2005-12-01 00:00:00

abstract：:Isorhynchophylline is one of the major alkaloids from the Uncaria hook possessing the effects of lowered blood pressure, vasodilatation and protection against ischemia-induced neuronal damage. However, the metabolic pathway of isorhynchophylline has not been fully reported yet. In this paper, the metabolism of isorhyn...

journal_title：Fitoterapia

authors： Chen F,Qi W,Sun J,Simpkins JW,Yuan D

更新日期：2014-09-01 00:00:00

abstract：:Two new guaiane-type sesquiterpenoids containing an interesting epoxy unit, daucuside (1) and daucusol (2) were isolated from the fruits of Daucus carota L. Their chemical structures were elucidated on the basis of MS, NMR spectroscopic analyses coupled with chemical degradation and they were also evaluated for the cy...

journal_title：Fitoterapia

authors： Fu HW,Zhang L,Yi T,Feng YL,Tian JK

更新日期：2010-07-01 00:00:00

abstract：:Picrasamide A (1), a new cinnamamide derivative, together with two new β-carboline alkaloids (2 and 3) and five known β-carboline alkaloids (4-8) were isolated from the stems of Picrasma quassioides (D. Don) Benn. Their structures were elucidated by detailed analyses of UV, IR, HRESIMS, and NMR data. Compound 1 was th...

journal_title：Fitoterapia

authors： Zhang J,Wang CX,Song XJ,Li S,Fan CL,Chen GD,Hu D,Yao XS,Gao H

更新日期：2019-11-01 00:00:00

abstract：:The antimicrobial activity of ethanol, acetone and aqueous extracts of the aerial parts of Pseudognaphalium moritzianum was evaluated. Ethanol and acetone extracts showed activity against Staphlococcus aureus, Enterococcus faecalis and Pseudomonas aeruginosa. The aqueous extract was active against S. aureus and P. aer...

journal_title：Fitoterapia

authors： Rangel D,Garcia I,Velasco J,Buitrago D,Velazco E

更新日期：2002-12-01 00:00:00

abstract：:In our previous study, RAPD (Random Amplified Polymorphic DNA) analysis revealed species-specific markers for three medicinal Echinacea species (Asteraceae): E. angustifolia DC., E. pallida (Nutt.) Nutt. and E. purpurea (L.) Moench. In the present work, we have converted a RAPD marker (750 bp) for E. purpurea into a S...

journal_title：Fitoterapia

authors： Adinolfi B,Chicca A,Martinotti E,Breschi MC,Nieri P

更新日期：2007-01-01 00:00:00

abstract：:Cinnamon is the dried bark of Cinnamomum cassia Presl, and its main component is cinnamaldehyde (CA). Decades of synthetic pesticide use to control parasitic nematodes that can harm plants has seriously polluted the environment and poses a risk to soil ecology, highlighting the need to develop natural biological pesti...

journal_title：Fitoterapia

authors： Lu L,Shu C,Chen L,Yang Y,Ma S,Zhu K,Shi B

更新日期：2020-10-01 00:00:00

abstract：AIM:The current study was designed to explore the mechanism of the prokinetic activity of Gentiopicroside (Ge), from Gentiana macrophylla Pall which is widely used to strengthen gastric motility in clinic. METHODS:Gastrointestinal motility disorder rats were induced by stress stimulation and the rats were treated with...

journal_title：Fitoterapia

authors： Ruan M,Yu B,Xu L,Zhang L,Long J,Shen X

更新日期：2015-06-01 00:00:00

abstract：:Three lignans, pinoresinol (1), 8-hydroxypinoresinol (2) and olivil (3) have been isolated from the leaves of Strophanthus gratus by reversed-phase HPLC. ...

journal_title：Fitoterapia

authors： Cowan S,Stewart M,Abbiw DK,Latif Z,Sarker SD,Nash RJ

更新日期：2001-01-01 00:00:00

abstract：:Three novel xanthonolignoid C-glycosides, glomexanthones A-C, with a trans-dihydrobenzofuran on B ring and a 2-hydroxymethyl-5-hydroxyl-2-pentenoic acid moiety in the sugar chain were isolated from an ethanol extract of Polygala glomerata. Their structures and absolute configurations were characterized by extensive NM...

journal_title：Fitoterapia

authors： Li CJ,Yang JZ,Yu SS,Zhao CY,Peng Y,Wang XL,Zhang DM

更新日期：2014-03-01 00:00:00