Nepetalactone content in shoot cultures of three endemic Nepeta species and the evaluation of their antimicrobial activity.

Abstract:

:Rapid micropropagation of Nepeta rtanjensis, N. sibirica and N. nervosa was performed. Qualitative and quantitative nepetalactone content in methanol extracts of in vitro grown plants was analysed by reverse-phase HPLC coupled with UV and MS detection. Only trans,cis-nepetalactone was detected in shoots of N. rtanjensis, while cis,trans-nepetalactone stereoisomer was present in N. sibirica. No nepetalactone was observed in shoots of N. nervosa. The antimicrobial activity of methanol extracts, against eight bacterial and eight fungal species, was evaluated. All the tested extracts showed significant antibacterial and strong antifungal activity. However, N. rtanjensis extract exhibited the best antimicrobial potential.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Nestorović J,Misić D,Siler B,Soković M,Glamoclija J,Cirić A,Maksimović V,Grubisić D

doi

10.1016/j.fitote.2010.03.007

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

621-6

issue

6

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(10)00066-3

journal_volume

81

pub_type

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