Abstract:
:Phytochemical study on rhizomes of Cimicifuga dahurica resulted in the isolation of nine new neolignan and phenylpropanoid glycosides, cimicifugasides A-E (1, 2, 7-9), cimicifugamides B-D (3-5), shomaside G (6) along with four known compounds (10-13). Their structures were identified by extensive spectroscopic analyses (1D-, 2D-NMR, MS, CD, IR, UV) and chemical methods. Their anti-inflammatory potentials were evaluated by measuring their effects on PGE2 production of LPS-stimulated RAW264.7 cells, and compounds 12 and 13 showed moderate anti-inflammatory activities.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Lu Q,Zhang WY,Pan DB,Shi DF,Pang QQ,Li HB,Yao XJ,Yao ZH,Yu Y,Yao XSdoi
10.1016/j.fitote.2019.03.023subject
Has Abstractpub_date
2019-04-01 00:00:00pages
485-492eissn
0367-326Xissn
1873-6971pii
S0367-326X(19)30301-6journal_volume
134pub_type
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