Abstract:
:Two novel eremophylane acetophenone conjugates, colletotricholides A (1) and B (2), were isolated from the solid fermentation cultures of an endophytic fungus Colletotrichum gloeosporioides XL1200 isolated from the aerial parts of Salvia miltiorrhiza. The chemical structures of 1-2 were characterized by extensive spectroscopic methods and single-crystal X-ray crystallography. Structurally, compounds 1-2 are two unusual eremophylane acetophenone conjugates originating from the hybrid pathways of polyketide synthase and sesquiterpene synthase. In addition, compounds 1-2 were inactive against tested pathogens.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Zhao WT,Liu QP,Chen HY,Zhao W,Gao Y,Yang XLdoi
10.1016/j.fitote.2020.104474subject
Has Abstractpub_date
2020-03-01 00:00:00pages
104474eissn
0367-326Xissn
1873-6971pii
S0367-326X(19)32464-5journal_volume
141pub_type
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