Anticoagulant flavonoid oligomers from the rhizomes of Alpinia platychilus.

abstract：:Seven oleanane-type triterpenoid saponins, tunicosaponins B-D (1-3), F-I (4-7), along with eight known triterpenoid saponins (8-15), were isolated from the roots of Psammosilene tunicoides. The structures of compounds 1-7 were determined by comprehensive spectroscopic analysis, including 1D and 2D NMR techniques, mass...

journal_title：Fitoterapia

authors： Wen B,Tian JM,Huang ZR,Xiao SJ,Yuan WL,Wang JX,Li HL,Xu XK,Shen YH

更新日期：2020-07-01 00:00:00

abstract：:Calcium-activated chloride channels (CaCCs) as a kind of widely expressed ion channels play crucial roles in a variety of physiological regulation. TMEM16A has been identified as the molecular basis of CaCCs in numerous cell types and is considered a new drug target for many diseases. Regulating the function of TMEM16...

journal_title：Fitoterapia

authors： Zhu X,Zhang W,Jin L,Zhang G,Yang H,Yu B

更新日期：2020-11-01 00:00:00

abstract：:Antimicrobial screening of Enantia polycarpa bark showed activity of the polar extracts against some microorganisms. ...

journal_title：Fitoterapia

authors： Ajali U

更新日期：2000-06-01 00:00:00

abstract：:The antioxidant activity of the methanol extract of Hypericum triquetrifolium Turra (Hypericaceae) aerial part and of flavonoids isolated therein, I3,II8-biapigenin, quercetin-3-O-galactoside, kaempferol-3-O-glycoside, (-)-epicatechin and hypericin, was evaluated. The IC(50) resulted between 0.062 and 1 mg/ml. ...

journal_title：Fitoterapia

authors： Conforti F,Statti GA,Tundis R,Menichini F,Houghton P

更新日期：2002-10-01 00:00:00

abstract：:Five new koumine-type alkaloids (1-5) along with six known ones were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated on the basis of NMR spectroscopy and electronic circular dichroism spectral analyses. The inhibitory effects of compounds 1-11 on the viabilit...

journal_title：Fitoterapia

authors： Zhang W,Zhang SY,Wang GY,Li NP,Chen MF,Gu JH,Zhang DM,Wang L,Ye WC

更新日期：2017-04-01 00:00:00

abstract：:Two novel eremophylane acetophenone conjugates, colletotricholides A (1) and B (2), were isolated from the solid fermentation cultures of an endophytic fungus Colletotrichum gloeosporioides XL1200 isolated from the aerial parts of Salvia miltiorrhiza. The chemical structures of 1-2 were characterized by extensive spec...

journal_title：Fitoterapia

authors： Zhao WT,Liu QP,Chen HY,Zhao W,Gao Y,Yang XL

更新日期：2020-03-01 00:00:00

abstract：:The isolation of five flavonol glycosides (1-5) from the flowers of Aconitum vulparia is reported, together with the 1H- and 13C-NMR spectral data in CD(3)OD of compound 3 and 5. ...

journal_title：Fitoterapia

authors： Fico G,Braca A,Morelli I,Tomè F

更新日期：2003-06-01 00:00:00

abstract：:The last few decades have seen an alarming rise in fungal infections, which currently represent a global health threat. Despite extensive research towards the development of new antifungal agents, only a limited number of antifungal drugs are available in the market. The routinely used polyene agents and many azole an...

journal_title：Fitoterapia

authors： Shreaz S,Wani WA,Behbehani JM,Raja V,Irshad M,Karched M,Ali I,Siddiqi WA,Hun LT

更新日期：2016-07-01 00:00:00

abstract：:Cassia occidentalis L. is an annual or perennial Ayurvedic plant which is used in several traditional medicines to cure various diseases. This weed has been known to possess antibacterial, antifungal, antidiabetic, anti-inflammatory, anticancerous, antimutagenic and hepatoprotective activity. A wide range of chemical ...

journal_title：Fitoterapia

authors： Yadav JP,Arya V,Yadav S,Panghal M,Kumar S,Dhankhar S

更新日期：2010-06-01 00:00:00

abstract：:An endophytic fungal strain named Trichoderma atroviride was isolated from the bulb of Lycoris radiata. Following cultivation on rice medium, a novel 3-amino-5-hydroxy-5-vinyl-2-cyclopenten-1-one dimer, atrichodermone A (1), a new cyclopentenone derivative, atrichodermone B (2), and a new sesquiterpene, atrichodermone...

journal_title：Fitoterapia

authors： Zhou P,Wu Z,Tan D,Yang J,Zhou Q,Zeng F,Zhang M,Bie Q,Chen C,Xue Y,Luo Z,Wang J,Zhu H,Zhang Y

更新日期：2017-11-01 00:00:00

abstract：:Five new benzylphenanthrenes, cremaphenanthrenes L-P (1-5) were isolated from the EtOAc-soluble extract of the tubers of Cremastra appendiculata. Their structures were elucidated based on the spectroscopic data and chemical methods. Compounds 1-5 were tested in vitro for their cytotoxic effects against colon (HCT-116)...

journal_title：Fitoterapia

authors： Liu L,Li J,Zeng KW,Jiang Y,Tu PF

更新日期：2015-06-01 00:00:00

abstract：:Three new clerodane type diterpenoids (2-4), together with one known analogues (1), were isolated from the tuberous roots of Tinospora sagittata (Oliv.) Gagnep. Compound 3 is an unusual clerodane diterpenoid with the carbonyl functionality at C-3, which represents the first example from this diterpenoid compounds clas...

journal_title：Fitoterapia

authors： Zhang G,Ma H,Hu S,Xu H,Yang B,Yang Q,Xue Y,Cheng L,Jiang J,Zhang J,Wang F,Zhang Y

更新日期：2016-04-01 00:00:00

abstract：:Nineteen secolignans (1-19), including five new ones (1-5), were isolated from the whole plant of Peperomia dindygulensis. Their structures including stereochemistry were determined by spectroscopic methods, in particular NMR and electronic CD (ECD) analysis. All the isolates were evaluated for their inhibitory activi...

journal_title：Fitoterapia

authors： Sun RF,Zhu CC,Yang Y,Yu NJ

更新日期：2017-10-01 00:00:00

abstract：:The present study investigated the effects of isopulegol, a monoterpene alcohol, in PTZ-induced convulsions and verified possible involved mechanisms. Saline, isopulegol or diazepam were intraperitonealy injected 30 min before PTZ. The latency for development of convulsions and mortality, as well as the mortality prot...

journal_title：Fitoterapia

authors： Silva MI,Silva MA,de Aquino Neto MR,Moura BA,de Sousa HL,de Lavor EP,de Vasconcelos PF,Macêdo DS,de Sousa DP,Vasconcelos SM,de Sousa FC

更新日期：2009-12-01 00:00:00

abstract：:Bergamot juice produces hypolipemic activity in rats though the mechanism remains unclear. Here we investigated on the effect of bergamot extract (BPF) in diet-induced hyperlipemia in Wistar rats and in 237 patients suffering from hyperlipemia either associated or not with hyperglycaemia. BPF, given orally for 30 days...

journal_title：Fitoterapia

authors： Mollace V,Sacco I,Janda E,Malara C,Ventrice D,Colica C,Visalli V,Muscoli S,Ragusa S,Muscoli C,Rotiroti D,Romeo F

更新日期：2011-04-01 00:00:00

abstract：:The effect of basil oil on the phagocytic capability and respiratory burst response of mouse peritoneal macrophages was studied. The oil inhibited the phagocytosis of opsonized sheep erythrocytes. This inhibition was both dose- and time-dependent and reverted 24 h after removing the extract from the culture medium. On...

journal_title：Fitoterapia

authors： Courrèges MC,Benencia F

更新日期：2002-08-01 00:00:00

abstract：:Different lines of experimental evidence indicate that treatment with extracts from and derivatives of Phaseolus vulgaris reduces intake of food, including highly palatable foods and beverages, in rats. The present study was designed to extend to mice these lines of evidence. To this end, CD1 mice were treated acutely...

journal_title：Fitoterapia

authors： Loi B,Fantini N,Colombo G,Gessa GL,Riva A,Bombardelli E,Morazzoni P,Carai MA

更新日期：2013-03-01 00:00:00

abstract：:The crude ethanol extract from the leaves of Zanthoxylum liebmannianum exhibited inhibitory effect on the reproduction of trophozoites of Entamoeba histolytica (IC(50)=3.48 microg/ml) and Giardia lamblia (IC(50)=58.00 microg/ml). From this extract, asarinin, hyperin, beta-sitosterol, and beta-sitosterol glucoside were...

journal_title：Fitoterapia

authors： Arrieta J,Reyes B,Calzada F,Cedillo-Rivera R,Navarrete A

更新日期：2001-03-01 00:00:00

abstract：:A new C(18)-phytosphingosine ceramide containing non-hydroxy fatty acid, armillaramide (1), has been isolated together with ergosterol peroxide from the fruiting bodies of the basidiomycete Armillaria mellea. Its structure was established as (2S,3S,4R)-2-hexadecanoylamino-octadecane-1,3,4-triol by spectroscopic and ch...

journal_title：Fitoterapia

authors： Gao JM,Yang X,Wang CY,Liu JK

更新日期：2001-12-01 00:00:00

abstract：:Three new xanthones, cylindroxanthones A-C (1-3), were isolated from the stem bark of Garcinia cylindrocarpa. The structures were established on the basis of spectroscopic analysis. The molecular structure of 1 was unequivocally confirmed by single-crystal X-ray diffraction analysis. These three xanthones were evaluat...

journal_title：Fitoterapia

authors： Sukandar ER,Ersam T,Fatmawati S,Siripong P,Aree T,Tip-pyang S

更新日期：2016-01-01 00:00:00

abstract：:The isolation of a new flavan, 5,7,4'-trihydroxy-8-ethoxycarbonylflavan (1), from the root of Daphne odora var. atrocaulis is reported. ...

journal_title：Fitoterapia

authors： Zhang W,Zhang W,Li T,Liu R,Li H,Chen H

更新日期：2004-12-01 00:00:00

abstract：:Herbal medicines are the most globally used type of medical drugs. Their high cultural acceptability is due to the experienced safety and efficiency over centuries of use. Many of them are still phytochemically less-investigated, and are used without standardization or quality control. Choosing SIROP KILMA, an authori...

journal_title：Fitoterapia

authors： Tshitenge DT,Ioset KN,Lami JN,Ndelo-di-Phanzu J,Mufusama JP,Bringmann G

更新日期：2016-04-01 00:00:00

abstract：:As part of our search for biologically active anti-osteoporotic agents that enhance the differentiation and mineralization of osteoblastic MC3T3-E1 cells, we identified the ginsenoside Rd as the most active compound among ginsenosides. In this study, we showed that Rd stimulates osteoblastic differentiation and minera...

journal_title：Fitoterapia

authors： Kim DY,Park YG,Quan HY,Kim SJ,Jung MS,Chung SH

更新日期：2012-01-01 00:00:00

abstract：:Four new sesquiterpene lactones, named artemargyinolides A-D (1-4), and seven known sesquiterpenoids (5-11) were isolated from Artemisia argyi. Their structures were elucidated based on the extensive analysis of spectroscopic data. The absolute configuration of 1 was assigned by X-ray crystallographic analysis. Compou...

journal_title：Fitoterapia

authors： Zhang LB,Lv JL

更新日期：2019-11-01 00:00:00

abstract：:Four new lignanamides, melongenamides A-D (1-4), together with six known ones (5-10), were isolated from the roots of Solanum melongena L. Their structures were elucidated on the basis of 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with the literature values. Compounds 2-8 exhi...

journal_title：Fitoterapia

authors： Sun J,Gu YF,Su XQ,Li MM,Huo HX,Zhang J,Zeng KW,Zhang Q,Zhao YF,Li J,Tu PF

更新日期：2014-10-01 00:00:00

abstract：:Citotoxicity (inhibition of cell division in fertilized eggs of Loxechinus albus) and general toxicity (using embryos of Artemia salina) of plants belonging to the genera Senecio, Deschampsia, Alstroemeria, Anarthrophyllum, Chloraea and Geranium were investigated. ...

journal_title：Fitoterapia

authors： Cuadra P,Furrianca M,Oyarzún A,Yáñez E,Gallardo A,Fajardo V

更新日期：2005-12-01 00:00:00

abstract：:European Hawthorn species (Crataegus spp.) are traditionally used for their demonstrated cardioprotective benefits. Most products are based on the compendial leaf and flower drug (LFD), which is standardised on the total flavonoid content (TF). In order to reduce variability associated with the wild plant origin and t...

journal_title：Fitoterapia

authors： Peschel W,Bohr C,Plescher A

更新日期：2008-01-01 00:00:00

abstract：:Diabetes is a worldwide healthy concern, which affects approximately 9% of the population. Tetrahydrocurcumin (THC) is the main metabolite of curcumin, which exerts the anti-diabetic activity. However, the underlying mechanism has not been clarified. In the research, we investigated whether THC could improve diabetes ...

journal_title：Fitoterapia

authors： Yuan T,Yin Z,Yan Z,Hao Q,Zeng J,Li L,Zhao J

更新日期：2020-10-01 00:00:00

abstract：:Two new alkaloidal metabolites, cordytakaoamides A (1) and B (2), as well as, 2-[(2-hydroxyethyl) amino] benzoic acid (3) and 2E-decenamide (4), and three known compounds (5-7) were isolated from ethyl acetate and n-butanol soluble portions of the entomopathogenic fungus, Cordyceps takaomontana NBRC 101754. Compounds ...

journal_title：Fitoterapia

authors： Hama M,Elshamy AI,Yoneyama T,Kasai Y,Yamamoto H,Tanigawa K,Oshiro A,Noji M,Ban S,Imagawa H,Umeyama A

更新日期：2019-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is highly prevalent among global populations, with an estimated number of infected patients being 170 million. Approximately 70-80% of patients acutely infected with HCV will progress to chronic liver disease, such as liver cirrhosis and hepatocellular carcinoma, which is a substantia...

journal_title：Fitoterapia

authors： Wahyuni TS,Widyawaruyanti A,Lusida MI,Fuad A,Soetjipto,Fuchino H,Kawahara N,Hayashi Y,Aoki C,Hotta H

更新日期：2014-12-01 00:00:00