Novel secolignans from Peperomia dindygulensis and their inhibitory activities on JAK-STAT signaling pathways.

abstract：:The methanol extract of Leucas aspera flowers, its fractions, the alkaloidal residue and the expressed flower juice, tested for antimicrobial activity, showed good antibacterial activity for methanol extract and methanol fraction with maximum activity for the alkaloidal residue. ...

journal_title：Fitoterapia

authors： Mangathayaru K,Lakshmikant J,Shyam Sundar N,Swapna R,Grace XF,Vasantha J

更新日期：2005-12-01 00:00:00

abstract：:Phytochemical investigations on Physalis. alkekengi L. var. franchetii, a widespread traditional Chinese medicine, led to the isolation and identification of three new sesquiterpenoids physalisitins A-C (1-3). Their structures were elucidated by NMR and HRESIMS analysis, and their absolute configurations were determin...

journal_title：Fitoterapia

authors： Zhang JL,Zhou FF,Li YZ,Feng T,Jiang LL,Jiang RW,Zhang XX,Li XD

更新日期：2020-03-01 00:00:00

abstract：:A new triterpene glycoside (1) along with the known intercedenside B (2) was isolated from the sea cucumber Pseudocolochirus violaceus. Glycoside 1 was elucidated as 3-O-{6-O-sodiumsulfate-3-O-methyl-beta-D-glucopyranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-[beta-D-xylopyranosyl(1-->2)]-beta-D-quinovopyranosyl-(1-->2...

journal_title：Fitoterapia

authors： Zhang SY,Tang HF,Yi YH

更新日期：2007-06-01 00:00:00

abstract：:Extracts of Hypericum, Passiflora and Valeriana are used for the treatment of mild depression and anxiety. We were interested whether a combination of Hypericum and Passiflora exerts comparable effects to Hypericum alone. We used two well-established models for investigating extracts for their anti-depressant activity...

journal_title：Fitoterapia

authors： Fiebich BL,Knörle R,Appel K,Kammler T,Weiss G

更新日期：2011-04-01 00:00:00

abstract：:Influenza poses a particular risk of severe outcomes in the elderly, the very young and those with underlying diseases. Tea polyphenols are the natural phenolic compounds in teas, and principally consist of catechins, proanthocyanidins, flavonols, and theaflavins, which antiviral activities have been reported recently...

journal_title：Fitoterapia

authors： Yang ZF,Bai LP,Huang WB,Li XZ,Zhao SS,Zhong NS,Jiang ZH

更新日期：2014-03-01 00:00:00

abstract：:We investigated the effect of caffeoylserotonin (CaS) on THP-1 monocyte migration and adhesion to fibronectin in response to MCP-1. CaS decreased monocyte adhesion and migration induced by MCP-1, together with CCR2 expression and α5β1 integrin, and activated β1 integrin expression on the cell surface. CaS also inhibit...

journal_title：Fitoterapia

authors： Yoon JH,Kim HE,Choi JY,Bae HJ,Lee SG

更新日期：2012-12-01 00:00:00

abstract：:Two new neo-clerodane diterpenoids have been isolated from the whole plant of Scutellaria barbata D. Don, and their structures were established by detailed spectral analyses as scutehenanine H (1) and 6-(2,3-epoxy-2-isopropyl-n-propoxyl)barbatin C (2). In vitro, the isolated two new compounds showed significant cytoto...

journal_title：Fitoterapia

authors： Dai SJ,Qu GW,Yu QY,Zhang DW,Li GS

更新日期：2010-10-01 00:00:00

abstract：:Aqueous extract of Pteris multifida showed scavenging activities on DPPH, hydroxyl radicals and reducing power. ...

journal_title：Fitoterapia

authors： Wang TC,Ti MC,Lo SC,Yang CC

更新日期：2007-04-01 00:00:00

abstract：:Lycocasuarines I-Q (1-9), nine new lycodine-type Lycopodium alkaloids were isolated from the aerial parts of Lycopodiastrum casuarinoides (Spring) Holub ex R.D.Dixit. Their structures were unambiguously determined via extensive spectroscopic analyses, including HRESIMS, NMR, and electronic circular dichroism (ECD). Th...

journal_title：Fitoterapia

authors： Zhu XL,Wang LL,Shi ZH,Xia D,Zhou ZB,Pan K

更新日期：2019-04-01 00:00:00

abstract：:The ethanolic extract of Lawsonia inermis leaves and lawsone tested for trypsin inhibitory activity showed an IC(50) value of 64.87 and 48.6 microg/ml, respectively. ...

journal_title：Fitoterapia

authors： Yogisha S,Samiulla DS,Prashanth D,Padmaja R,Amit A

更新日期：2002-12-01 00:00:00

abstract：:Gossypol is a yellow polyphenol isolated from cotton seeds. It has the antitumor activity and it is being tested to treat prostate cancer. However, its underlying mechanisms are still not well understood. The present study investigated the inhibitory effects of gossypol acetate on rat 5α-reductase 1, 3α-hydroxysteroid...

journal_title：Fitoterapia

authors： Cao S,Wang G,Ge F,Li X,Zhu Q,Ge RS,Wang Y

更新日期：2019-03-01 00:00:00

abstract：:Bakuchicin is a furanocoumarin isolated from the seeds of Psoralea corylifolia, which is used in oriental medicine. However, limited information on the pharmacokinetics of bakuchicin is available and in addition, no determined method has been devised to quantify bakuchicin levels in the plasma. In the present study, w...

journal_title：Fitoterapia

authors： Jo JH,Kim JH,Lee HS,Jeong GS,Lee JM,Lee S

更新日期：2017-07-01 00:00:00

abstract：:Two new glycosides, 2-methyl-L-erythritol-4-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (1) and 2-methyl-L-erythritol-1-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (2), along with two known triterpenoids (3-4), four quinic acid derivatives (5-8) and one flavonoid (9) were isolated from the fruit of Gardenia jasminoides....

journal_title：Fitoterapia

authors： Yang L,Peng K,Zhao S,Zhao F,Chen L,Qiu F

更新日期：2013-09-01 00:00:00

abstract：:Two new clerodane diterpenoids 2 beta-methoxy-cleroda-3,13-dien-18-carboxy-15,16-olide (1) and 15 xi-methoxy-cleroda-3,12-dien-18-carboxy-15,16-olide (2) and one new nitrogen-containing clerodane diterpenoid 15-oxo-echinophyllin A (3), along with six known compounds, namely, echinophyllin A, (-)-patagonic acid, tyroso...

journal_title：Fitoterapia

authors： Wang W,Ali Z,Li XC,Smillie TA,Guo DA,Khan IA

更新日期：2009-10-01 00:00:00

abstract：:Diplacone (1) and mimulone (2), two geranylated flavanones, have previously shown anti-inflammatory and antiradical activity in vitro. The present study aimed to evaluate their activity in vivo on a model of colitis induced in Wistar rats by an oral administration of dextran sulfate sodium (DSS). Diplacone (1) and mim...

journal_title：Fitoterapia

authors： Vochyánová Z,Bartošová L,Bujdáková V,Fictum P,Husník R,Suchý P,Šmejkal K,Hošek J

更新日期：2015-03-01 00:00:00

abstract：:Rubus ideaus L., a member of the Rosaceae family, is popular for its distinctive flavor and attractive red color. In order to explore the functional factors possibly presented in the fruit, seven new benzofuran neolignans (1a/1b-3a/3b and 4b), together with one known neolignan 4a, were isolated from the fruit of R. id...

journal_title：Fitoterapia

authors： Zhou L,Xi YF,Wang W,Lin B,Wang XB,Huang XX,Song SJ

更新日期：2018-06-01 00:00:00

abstract：:Five new phthalides (1-4, 6), two new natural products (5, 7) and five known phthalides (8-12) were isolated from the aerial parts of Ligusticum sinense Oliv cv. Chaxiong. Their structures were elucidated by HR-ESI-MS, UV, IR, 1D and 2D NMR (HSQC, HMBC, (1)H-(1)H COSY, NOESY) methods. The absolute configurations were ...

journal_title：Fitoterapia

authors： Wei Q,Yang J,Ren J,Wang A,Ji T,Su Y

更新日期：2014-03-01 00:00:00

abstract：:A new cardenolide, 16,17-dihydroneridienone 3-O-beta-D-glucopyranosyl-(1-->6)-O-beta-D-galactopyranoside (1), was isolated from the roots of Terminalia arjuna. ...

journal_title：Fitoterapia

authors： Yadav RN,Rathore K

更新日期：2001-05-01 00:00:00

abstract：:The ecological role of maytansine, an important antineoplastic and antimicrobial compound with high cytotoxicity, particularly as a chemical defense compound has remained elusive since its discovery in the 1970s in Maytenus and Putterlickia plants. In the present study, we have used MALDI-imaging-HRMS to visualize the...

journal_title：Fitoterapia

authors： Eckelmann D,Kusari S,Spiteller M

更新日期：2017-06-01 00:00:00

abstract：:Four pairs of racemic phenylpropanoids (1a/1b-4a/4b), including five new compounds (1a/1b, 2a, 3a, and 4a) were obtained from the root barks of Ailanthus altissima (Mill.) Swingle. Their structures were determined by comprehensive spectroscopic analyses. The absolute configurations of the enantiomers were determined b...

journal_title：Fitoterapia

authors： Yan ZY,Chen JJ,Duan ZK,Yao GD,Lin B,Wang XB,Huang XX,Song SJ

更新日期：2018-10-01 00:00:00

abstract：:It has been reported that icariin and icariside II, two flavonoid glycosides coming from herba epimedii, which have a closely structural relationship, show some pharmacological effects such as preventing osteoporosis, cancer and depression. The content of natural icariside II is very low in herba epimedii, but it is t...

journal_title：Fitoterapia

authors： Xia Q,Xu D,Huang Z,Liu J,Wang X,Wang X,Liu S

更新日期：2010-07-01 00:00:00

abstract：:Cyclotides describe a unique cyclic peptide family that displays a broad range of biological activities including uterotonic, anti-bacteria, anti-cancer and anti-HIV. The vigno cyclotides consist of vigno 1-10 were reported recently from Viola ignobilis. In the present study, we examined the effects of vigno 5, a natu...

journal_title：Fitoterapia

authors： Esmaeili MA,Abagheri-Mahabadi N,Hashempour H,Farhadpour M,Gruber CW,Ghassempour A

更新日期：2016-03-01 00:00:00

abstract：:Four known flavonoids were isolated from the aerial parts of Salvia moorcroftiana. ...

journal_title：Fitoterapia

authors： Ahmad VU,Ali Z,Zahid M,Alam N,Saba N,Khan T,Qaisar M,Nisar M

更新日期：2000-02-01 00:00:00

abstract：:Two new depsidones, schomburgdepsidones A and B (1 and 2), and one new xanthone, schomburgxanthone A (3), together with eight known compounds (4-11) were isolated from the roots of Garcinia schomburgkiana. Their chemical structures were established on the basis of spectroscopic analysis. The in vitro cytotoxicity of a...

journal_title：Fitoterapia

authors： Sukandar ER,Siripong P,Khumkratok S,Tip-Pyang S

更新日期：2016-06-01 00:00:00

abstract：:Australian native plants have a long history of therapeutic use in indigenous cultures, however, they have been poorly studied scientifically. We analysed the effects of 14 plant derived compounds from the species Pilidiostigma glabrum, Myoporum montanum, Geijera parviflora, and Rhodomyrtus psidioides for their potent...

journal_title：Fitoterapia

authors： Adams DH,Shou Q,Wohlmuth H,Cowin AJ

更新日期：2016-03-01 00:00:00

abstract：:A phytochemical investigation on the leaves of Tripterygium wilfordii Hook. F. was conducted, leading to the isolation of five undescribed dihydro-β-agarofuran sesquiterpenoids (1-5) and one known analogue (6). Their structures were determined by comprehensive spectroscopic analyses. The absolute configurations of the...

journal_title：Fitoterapia

authors： Zhao P,Lin B,Hou ZL,Zhou L,He QJ,Yao GD,Huang XX,Song SJ

更新日期：2020-04-01 00:00:00

abstract：:Although the nature-identical chemical compounds are cheaper, they not always repeat biological activity of plant origin natural chemical compounds, often react allergies and resistance of microorganisms. The aim of this study was to investigate effects of Juniperus communis origin α-pinene with different enantiomeric...

journal_title：Fitoterapia

authors： Ložienė K,Švedienė J,Paškevičius A,Raudonienė V,Sytar O,Kosyan A

更新日期：2018-06-01 00:00:00

abstract：:Three new caged polyprenylated benzophenone derivatives named burlemarxiones D-F (1-3) were isolated from the hexane extract of Clusia burle-marxii trunks. Burlemarxione D (1) contains the tetracyclo[8.3.1.03,11.05,10]tetradecane core skeleton also observed for burlemarxione A, its probable immediate precursor. Howeve...

journal_title：Fitoterapia

authors： Ferraz CG,Ribeiro PR,Mendonça R,Silveira ER,Cruz FG

更新日期：2020-10-16 00:00:00

abstract：:European Hawthorn species (Crataegus spp.) are traditionally used for their demonstrated cardioprotective benefits. Most products are based on the compendial leaf and flower drug (LFD), which is standardised on the total flavonoid content (TF). In order to reduce variability associated with the wild plant origin and t...

journal_title：Fitoterapia

authors： Peschel W,Bohr C,Plescher A

更新日期：2008-01-01 00:00:00

abstract：:One new resveratrol analogue, 1-(3',4',5'-trimethoxyphenyl)-2-methoxy-2-(4″-methoxyphenyl)-ethane-1-ol (1), and two new prenylisoflavones, 4'-hydroxy-5,7-dimethoxy-6-(3-methyl-2-butenyl)-isoflavone (2), and derrubon 5-methyl ether (3), together with 17 known compounds including one new natural product, 5,7-dihydroxy-3...

journal_title：Fitoterapia

authors： Zhang HX,Lunga PK,Li ZJ,Dai Q,Du ZZ

更新日期：2014-06-01 00:00:00