Abstract:
:Lycocasuarines I-Q (1-9), nine new lycodine-type Lycopodium alkaloids were isolated from the aerial parts of Lycopodiastrum casuarinoides (Spring) Holub ex R.D.Dixit. Their structures were unambiguously determined via extensive spectroscopic analyses, including HRESIMS, NMR, and electronic circular dichroism (ECD). The new alkaloids were evaluated for their in vitro inhibitory activity against acetylcholinesterase (AChE). Compounds 3, 5-8 exhibited marginal or weak activities with IC50 values ranging from 97.2 to 171.9 μM.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Zhu XL,Wang LL,Shi ZH,Xia D,Zhou ZB,Pan Kdoi
10.1016/j.fitote.2019.03.027subject
Has Abstractpub_date
2019-04-01 00:00:00pages
474-480eissn
0367-326Xissn
1873-6971pii
S0367-326X(19)30411-3journal_volume
134pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract::The high edible oil content of Xanthoceras sorbifolia Bunge seeds contributes to its economic value. In this study, we analysed the barrigenol-like triterpenoids derived from X. sorbifolia husks. We also identified anti-tumour agents that could enhance the health benefits and medicinal value of X. sorbifolia. We isola...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.11.002
更新日期:2017-01-01 00:00:00
abstract::A new arylnaphthalene lignan, named furfuracin, was isolated from the leaves of Knema furfuracea (Myristicaceae), whereas 7 known compounds including (+)-trans-1,2-dihydrodehydroguaiaretic acid, fragransin A(2), biochanin A, gingkolic acid, anarcardic acid, 2-hydroxy-6-(12-phenyldodecyl)-benzoic acid and 2-hydroxy-6-(...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2009.05.005
更新日期:2009-09-01 00:00:00
abstract::A new compound, 3beta,25-epoxy-3alpha-hydroxy-22beta-isobutanoyloxyolean-12-ene-28-oic acid (1), and two known triterpenoids lantanilic acid (2) and camaric acid (3) were isolated from the stem and leaves of Lantana cujabensis. Their structures were elucidated by spectroscopic methods. The ethanol extracts did not sho...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2004.02.005
更新日期:2004-06-01 00:00:00
abstract::Acteoside, which belongs to the family of phenylethanoid glycosides (PhGs), has extensive biological activities, including strong antioxidant, anti-inflammatory, hepatoprotect, and cell apoptosis regulation. Like other PhGs compounds, the fate of acteoside in the gut for both parent polyphenols and their degradation p...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.05.004
更新日期:2016-07-01 00:00:00
abstract::Four new taraxerane triterpenoids, 1β,3β-dihydroxy-11α,12α-oxidotaraxerane (1), 28-hydroxy-11α,12α-oxidotaraxerane-3-one (2), 3β-hydroxy-11α,12α-oxidotaraxerane-28-al (3), and 3-O-acetyl-11α,12α-oxidotaraxerane-28-al (4), together with three known compounds 3β-hydroxy-11α,12α-oxidotaraxerane (5), 3β,28-dihydroxy-11α,1...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.09.009
更新日期:2012-01-01 00:00:00
abstract::Phytochemical investigation of methanolic extract of the whole plants of Vaccinium emarginatum allowed for the characterization of one epicatechin derivative (1) that was isolated from a natural source for the first time and three new flavonoids, emarginin A (2), emarginin B (3), and emarginin C (4), together with 11 ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104446
更新日期:2020-03-01 00:00:00
abstract::The use of herbal drugs for the prevention and treatment of various health ailments has been in practice from time immemorial. Generally it is believed that the risk associated with herbal drugs is very less, but reports on serious reactions are indicating to the need for development of effective marker systems for is...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2010.02.001
更新日期:2010-09-01 00:00:00
abstract::Bergenin, a major constituent of Caesalpinia digyna Rottler (Leguminosae) was isolated from its roots and was characterized by comparing its melting point and spectroscopic data (IR, (1)H, (13)C, Mass Spectra) with standard bergenin. Isolated bergenin was then evaluated for antidiabetic (Type 2) activity in streptozot...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.12.008
更新日期:2012-03-01 00:00:00
abstract::Fruit's decoctions of Passiflora edulis and P. foetida var. albiflora were evaluated for the inhibition of activity of gelatinase MMP-2 and MMP-9, two metallo-proteases involved in the tumour invasion, metastasis and angiogenesis. Both water extracts, at different concentrations, inhibited the enzymes. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(03)00023-6
更新日期:2003-04-01 00:00:00
abstract::There is growing evidence that motherwort (Leonurus japonicus Houtt.), and Chinese patent medicines derived from motherwort, alleviate postpartum uterine subinvolution, as well as the effects on myocardial and cerebral ischemic injuries. We hypothesized that these beneficial effects of motherwort may be related to ang...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.05.002
更新日期:2018-07-01 00:00:00
abstract::Two triglycerides, both bearing polyunsaturated fatty acid residues, were isolated from the hexane extract of Urena lobata. One of them is characterized by the presence of three different polyunsaturated fatty acids. Their structures were studied with spectral methods. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2006.03.010
更新日期:2006-06-01 00:00:00
abstract::Three undescribed polycyclic polyprenylated acylphloroglucinols (PPAPs) and three tocotrienols derivatives, named as paucinochymol A-F (1-3 and 10-12), together with six known PPAPs, were isolated from the fruits of Garcinia paucinervis. Their structures and absolute configurations were determined by extensive NMR ana...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2020.104688
更新日期:2020-10-01 00:00:00
abstract::Five new koumine-type alkaloids (1-5) along with six known ones were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated on the basis of NMR spectroscopy and electronic circular dichroism spectral analyses. The inhibitory effects of compounds 1-11 on the viabilit...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2017.03.004
更新日期:2017-04-01 00:00:00
abstract::Crude CH2Cl2 extract from leaves of Piper laevicarpu (Piperaceae) displayed antitrypanosomal activity against trypomastigote forms of Trypanosoma cruzi (Y strain) and antimicrobial potential against Cryptococcus gattii (strain-type WM 178). Bioactivity-guided fractionation of crude extract afforded one new natural bio...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.04.005
更新日期:2016-06-01 00:00:00
abstract::Five polyketides, paralactonic acids A-E (1-5) were isolated from Paraconiothyrium sp. SW-B-1, an endophytic fungus isolated from the seaweed, Chondrus ocellatus Holmes. Their structures were determined by various spectroscopic methods, predominantly by 2D NMR spectroscopic analyses. The absolute configurations of com...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.11.017
更新日期:2019-01-01 00:00:00
abstract::The antioxidant activity of the methanol extract of Hypericum triquetrifolium Turra (Hypericaceae) aerial part and of flavonoids isolated therein, I3,II8-biapigenin, quercetin-3-O-galactoside, kaempferol-3-O-glycoside, (-)-epicatechin and hypericin, was evaluated. The IC(50) resulted between 0.062 and 1 mg/ml. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(02)00162-4
更新日期:2002-10-01 00:00:00
abstract::The isolation of cinchonicine-derived alkaloids epicinchonicinol (1), cinchonidicinol (2) and a mixture of dihydrocinchonicinol and dihydrocinchonidicinol (3) from the dried bark of Ladenbergia oblongifolia, is reported along with (1)H and (13)C-NMR data. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(01)00298-2
更新日期:2001-08-01 00:00:00
abstract::A total of 58 fungal isolates, belonging to 24 genera, were obtained from the leaves, stems and roots of Ginkgo biloba L.. Among them, one endophytic fungal strain, Penicillium cataractum SYPF 7131, displayed the strongest antibacterial activity. Four new compounds (1-4) were isolated from the strain fermentation brot...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.05.033
更新日期:2018-07-01 00:00:00
abstract::A new flavone, 4'-hydroxy-6,7-methylenedioxy-3-methoxyflavone 1, and two other nucleosides, ribavirin 2 and adenosine 3, were isolated from the leaves of Dulacia egleri. The nucleosides were identified by spectroscopic techniques (1D, 2D-NMR) while the structure of the flavonoid was established by 1D, 2D-NMR analysis,...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.08.005
更新日期:2019-01-01 00:00:00
abstract::Methanol extract of the stem bark of Hymenodictyon parvifolium was tested for its antifungal and antibacterial activity. The extract was found to have inhibitory effect against all the pathogens tested. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(02)00176-4
更新日期:2002-10-01 00:00:00
abstract::Five new megastigmane glycosides, urenalobasides A-E (1-5), together with 11 known ones (6-16) were isolated from Urena lobata. Their structures were determined by extensive spectroscopic and spectrometric data (1D and 2D NMR, IR, and HRESIMS) and calculated electronic circular dichroism method. Compounds 1 and 2 are ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2018.02.017
更新日期:2018-06-01 00:00:00
abstract::Aloe barbadensis Mill has been used as food and medicine for a long time. In order to investigate the chemical constituents of A. barbadensis and their inhibitory activities towards phosphodiesterase-4D (PDE4D), 70% methanol extract of the dried A. barbadensis powder was employed. Phytochemical investigation has led t...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.08.027
更新日期:2013-12-01 00:00:00
abstract::In a two-microelectrode voltage clamp assay with Xenopus laevis oocytes, a petroleum ether extract (100 μg/mL) of the resin of Boswellia thurifera (Burseraceae) potentiated GABA-induced chloride currents (IGABA) through receptors of the subtype α₁β₂γ₂s by 319.8% ± 79.8%. With the aid of HPLC-based activity profiling, ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.09.002
更新日期:2014-12-01 00:00:00
abstract::A new monodesmosidic spirostanol saponin, along with three known saponins was isolated from Agave macroacantha Zucc leaves. The structure of the new saponin was established as hecogenin-3-O-alpha-L-rhamnopyranosyl (1-->4) beta-D-xylopyranosyl (1-->3)[beta-D-glucopyranosyl (1-->2)] beta-D-glucopyranosyl (1-->4) beta-D-...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2009.11.002
更新日期:2010-07-01 00:00:00
abstract::Five rare dichloro aromatic polyketides (1-5) were obtained from an endophytic fungus Penicillium sp., along with five known metabolites (6-10). Their structures were elucidated by extensive spectroscopic analysis, Mosher methods, as well as [Rh2(OCOCF3)4]-induced electronic circular dichroism (ECD) experiments. Compo...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.11.008
更新日期:2017-01-01 00:00:00
abstract::Six Patagonian plants were screened for proteolytic activity: Colliguaja integerrima, Euphorbia collina, E. peplus and Stillingia patagonica (Euphorbiaceae), Philibertia gilliesii (Asclepiadaceae) and Grindelia chiloensis (Asteraceae). P. gilliesii extracts showed the highest specific activity, followed by S. patagoni...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(03)00146-1
更新日期:2003-09-01 00:00:00
abstract::Flos Chrysanthemi (the flower of Chrysanthemum morifolium Ramat.) is widely used in China as a food and traditional Chinese medicine for many diseases. Luteolin and apigenin are two main bioactive components in Flos Chrysanthemi, and chrysoeriol and diosmetin are two methylated metabolites of luteolin in vivo by cathe...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.09.011
更新日期:2012-12-01 00:00:00
abstract::Five new guaiane-type sesquiterpenoids were obtained from the roots of Daphne genkwa. Their gross structures were established by extensive spectroscopic analyses. Attempts on the assignment of the relative configurations were unsuccessful when based on the NOESY correlations. Therefore, NMR chemical shift calculations...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2019.104352
更新日期:2019-10-01 00:00:00
abstract::The aqueous extract of the leaves of Musanga cecropioides did not affect ache-induced contractile response, but produced significant inhibition of the twitch and pendular movement of the rat and rabbit smooth muscles, respectively, and reduced writhing induced by acetic acid in mice. ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/s0367-326x(99)00130-6
更新日期:2000-04-01 00:00:00
abstract::One alkyl glycoside, saussurostelloside A (1), two phenolic glycosides, saussurostellosides B1 (2) and B2 (3), and 27 known compounds, including eleven flavonoids, seven phenolics, six lignans, one neolignan, one phenethyl glucoside and one fatty acid, were isolated from an ethanol extract of Saussurea stella (Asterac...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.03.027
更新日期:2013-07-01 00:00:00