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Five new koumine-type alkaloids from the roots of Gelsemium elegans.

Abstract：

:Five new koumine-type alkaloids (1-5) along with six known ones were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated on the basis of NMR spectroscopy and electronic circular dichroism spectral analyses. The inhibitory effects of compounds 1-11 on the viability of three tumor cell lines (A-649, HepG2, and HuH7) were evaluated by the MTT assay.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Zhang W,Zhang SY,Wang GY,Li NP,Chen MF,Gu JH,Zhang DM,Wang L,Ye WC

doi

10.1016/j.fitote.2017.03.004

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

112-117

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(16)31058-9

journal_volume

118

pub_type

杂志文章

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