Abstract:
:Four new compounds, including three new steroids (1-3) and one new sesquiterpene (6), and two new natural products (4-5), as well as three known steroids (7-9) were isolated from the twigs of Turraea pubescens. Compounds 3-5 are C₂₂ steroids isolated from the Meliaceae family for the first time. Their structures were elucidated by extensive NMR and MS analyses. Compound 1 exhibited inhibitory activity against lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells with an IC₅₀ value of 11.5 μM.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Yuan CM,Tang GH,Wang XY,Zhang Y,Cao MM,Li XH,Li Y,Li SL,Di YT,He HP,Hao XJ,Hua HMdoi
10.1016/j.fitote.2013.07.006subject
Has Abstractpub_date
2013-10-01 00:00:00pages
119-25eissn
0367-326Xissn
1873-6971pii
S0367-326X(13)00177-9journal_volume
90pub_type
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