Two new diterpenoids and other constituents from Isodon rubescens.

abstract：:The methanol extracts of Clematis papuasica leaves and stem bark and of Nauclea obversifolia leaves, stem and root barks showed awide spectrum of antibacterial activity which was increased on fractionation (petrol, dichloromethane, ethyl acetate), the ethyl acetate fractions being in all cases the most effective. None...

journal_title：Fitoterapia

authors： Khan MR,Kihara M,Omoloso AD

更新日期：2001-06-01 00:00:00

abstract：:The crude ethanol extract from the leaves of Zanthoxylum liebmannianum exhibited inhibitory effect on the reproduction of trophozoites of Entamoeba histolytica (IC(50)=3.48 microg/ml) and Giardia lamblia (IC(50)=58.00 microg/ml). From this extract, asarinin, hyperin, beta-sitosterol, and beta-sitosterol glucoside were...

journal_title：Fitoterapia

authors： Arrieta J,Reyes B,Calzada F,Cedillo-Rivera R,Navarrete A

更新日期：2001-03-01 00:00:00

abstract：:Gossypol is a yellow polyphenol isolated from cotton seeds. It has the antitumor activity and it is being tested to treat prostate cancer. However, its underlying mechanisms are still not well understood. The present study investigated the inhibitory effects of gossypol acetate on rat 5α-reductase 1, 3α-hydroxysteroid...

journal_title：Fitoterapia

authors： Cao S,Wang G,Ge F,Li X,Zhu Q,Ge RS,Wang Y

更新日期：2019-03-01 00:00:00

abstract：:Lanaroflavone (1), a biflavonoid isolated from the methanol extract of the aerial part of Campnosperma panamense by bioguided fractionation, has been assessed for in vitro antiprotozoal activity. Lanaroflavone showed both antimalarial and leishmanicidal activities, but was inactive against Chagas disease vector, Trypa...

journal_title：Fitoterapia

authors： Weniger B,Vonthron-Sénécheau C,Arango GJ,Kaiser M,Brun R,Anton R

更新日期：2004-12-01 00:00:00

abstract：:The present study was designed to verify whether frutalin (FTL) affords gastroprotection against the ethanol-induced gastric damage and to examine the underlying mechanism(s). Gastric damage was induced by intragastric administration of 0.2 ml of ethanol (96%). Mice in groups were pretreated with FTL (0.25, 0.5 and 1 ...

journal_title：Fitoterapia

authors： de Vasconcellos Abdon AP,Coelho de Souza G,Noronha Coelho de Souza L,Prado Vasconcelos R,Araújo Castro C,Moreira Guedes M,Pereira Lima RC Jr,de Azevedo Moreira R,de Oliveira Monteiro-Moreira AC,Rolim Campos A

更新日期：2012-04-01 00:00:00

abstract：:Four new sesquiterpene lactones, named artemargyinolides A-D (1-4), and seven known sesquiterpenoids (5-11) were isolated from Artemisia argyi. Their structures were elucidated based on the extensive analysis of spectroscopic data. The absolute configuration of 1 was assigned by X-ray crystallographic analysis. Compou...

journal_title：Fitoterapia

authors： Zhang LB,Lv JL

更新日期：2019-11-01 00:00:00

abstract：:Chemical investigation of the liquid culture of the endophytic fungus Bipolaris sorokiniana A606, which was isolated from the medicinal plant Pogostemon cablin resulted in the isolation of four new cytotoxic compounds, named isocochlioquinones D-E (1-2) and cochlioquinones G-H (3-4), along with five known cochlioquino...

journal_title：Fitoterapia

authors： Wang M,Sun ZH,Chen YC,Liu HX,Li HH,Tan GH,Li SN,Guo XL,Zhang WM

更新日期：2016-04-01 00:00:00

abstract：:The effect of berberine hydrochloride (BBR) on inducible cyclooxygenase-2 (COX-2) in small intestinal mucosa and related mechanisms was investigated in a rat model of acute endotoxemia. The results showed that lipopolysaccharide (LPS) increased COX-2 expression, whereas SB202190 and BBR curtailed it. LPS increased pho...

journal_title：Fitoterapia

authors： Feng AW,Yu C,Mao Q,Li N,Li QR,Li JS

更新日期：2011-10-01 00:00:00

abstract：:Diabetes is a worldwide healthy concern, which affects approximately 9% of the population. Tetrahydrocurcumin (THC) is the main metabolite of curcumin, which exerts the anti-diabetic activity. However, the underlying mechanism has not been clarified. In the research, we investigated whether THC could improve diabetes ...

journal_title：Fitoterapia

authors： Yuan T,Yin Z,Yan Z,Hao Q,Zeng J,Li L,Zhao J

更新日期：2020-10-01 00:00:00

abstract：:Ten coumarins were isolated from Peucedanum luxurians. The rare coumarins stenocarpin, stenocarpin isobutyrate, officinalin, officinalin isobutyrate, 8-methoxypeucedanin and the known xanthotoxin, isoimperatorin, bergaptene, peucedanin and cnidilin were isolated. All isolated compound were identified by means of spect...

journal_title：Fitoterapia

authors： Chinou I,Widelski J,Fokialakis N,Magiatis P,Glowniak K

更新日期：2007-09-01 00:00:00

abstract：:Acteoside, which belongs to the family of phenylethanoid glycosides (PhGs), has extensive biological activities, including strong antioxidant, anti-inflammatory, hepatoprotect, and cell apoptosis regulation. Like other PhGs compounds, the fate of acteoside in the gut for both parent polyphenols and their degradation p...

journal_title：Fitoterapia

authors： Su D,Li W,Xu Q,Liu Y,Song Y,Feng Y

更新日期：2016-07-01 00:00:00

abstract：:European Hawthorn species (Crataegus spp.) are traditionally used for their demonstrated cardioprotective benefits. Most products are based on the compendial leaf and flower drug (LFD), which is standardised on the total flavonoid content (TF). In order to reduce variability associated with the wild plant origin and t...

journal_title：Fitoterapia

authors： Peschel W,Bohr C,Plescher A

更新日期：2008-01-01 00:00:00

abstract：:Two spiro paclitaxel-mimics consisting only of an oxetane D-ring and a C-13 side chain were designed and synthesized on the basis of analysis of structure-activity relationships (SAR) of paclitaxel. In vitro microtubule-stabilizing and antiproliferative assays indicated a moderate weaker activity of the mimics than pa...

journal_title：Fitoterapia

authors： Chen XX,Gao F,Wang Q,Huang X,Wang D

更新日期：2014-01-01 00:00:00

abstract：:Nineteen secolignans (1-19), including five new ones (1-5), were isolated from the whole plant of Peperomia dindygulensis. Their structures including stereochemistry were determined by spectroscopic methods, in particular NMR and electronic CD (ECD) analysis. All the isolates were evaluated for their inhibitory activi...

journal_title：Fitoterapia

authors： Sun RF,Zhu CC,Yang Y,Yu NJ

更新日期：2017-10-01 00:00:00

abstract：:The flavonoid fraction of Tephrosia purpurea (FFTP) was studied for its effect on cellular and humoral functions and on macrophage phagocytosis in mice. Oral administration of FFTP (10-40 mg/kg) significantly inhibited sheep red blood cells (SRBC)-induced delayed-type hypersensitivity reactions. It also produced a sig...

journal_title：Fitoterapia

authors： Damre AS,Gokhale AB,Phadke AS,Kulkarni KR,Saraf MN

更新日期：2003-04-01 00:00:00

abstract：:Thuja occidentalis L. is indigenous for Northern America and commonly cultivated in Europe. Raw materials obtained from this tree are widely applied in the ethnomedicine and phytotherapy of numerous ailments, incl. scurvy, cystitis, rheumatism and cancer. Despite wide medicinal applications of Thuja occidentalis, stil...

journal_title：Fitoterapia

authors： Pudełek M,Catapano J,Kochanowski P,Mrowiec K,Janik-Olchawa N,Czyż J,Ryszawy D

更新日期：2019-04-01 00:00:00

abstract：:Four known flavonoids were isolated from the aerial parts of Salvia moorcroftiana. ...

journal_title：Fitoterapia

authors： Ahmad VU,Ali Z,Zahid M,Alam N,Saba N,Khan T,Qaisar M,Nisar M

更新日期：2000-02-01 00:00:00

abstract：:Aloe vera gel is a familiar ingredient in a range of widely available and advertisement healthcare and cosmetic products. As to date there are no documented reports on the standardization of A. vera gel and the following study is an attempt in this direction. A. vera gel was evaluated for its aloeverose content for th...

journal_title：Fitoterapia

authors： Lobo R,Prabhu KS,Shirwaikar A,Ballal M,Balachandran C,Shirwaikar A

更新日期：2010-06-01 00:00:00

abstract：:Three new secoiridoids, swermacrolactones A-C (1-3), together with fourteen known compounds were isolated from Swertia macrosperma. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, MS, 1D and 2D NMR). By anti-HBV assay on the Hep G 2.2.15 cell line in vitro, the most active compound,...

journal_title：Fitoterapia

authors： Wang HL,Geng CA,Ma YB,Zhang XM,Chen JJ

更新日期：2013-09-01 00:00:00

abstract：:A screening was conducted with 26 plants collected in the Brazilian southeast region, to identify plant extracts with antibacterial properties against Aeromonas hydrophila, Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus. Initially, the agar diffusion method was employed. Then, those extracts prese...

journal_title：Fitoterapia

authors： Oliveira DF,Pereira AC,Figueiredo HC,Carvalho DA,Silva G,Nunes AS,Alves DS,Carvalho HW

更新日期：2007-02-01 00:00:00

abstract：:A new triterpene glycoside (1) along with the known intercedenside B (2) was isolated from the sea cucumber Pseudocolochirus violaceus. Glycoside 1 was elucidated as 3-O-{6-O-sodiumsulfate-3-O-methyl-beta-D-glucopyranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-[beta-D-xylopyranosyl(1-->2)]-beta-D-quinovopyranosyl-(1-->2...

journal_title：Fitoterapia

authors： Zhang SY,Tang HF,Yi YH

更新日期：2007-06-01 00:00:00

abstract：:alpha(2)beta(1) and alpha(IIb)beta(3) integrins, that support platelet adhesion to collagen and fibrinogen, respectively, share common signaling molecules. The effect of quercetin on platelet static adhesion to collagen and fibrinogen was assessed and correlated with its kinase inhibitory activity. Quercetin strongly ...

journal_title：Fitoterapia

authors： Navarro-Núñez L,Lozano ML,Martínez C,Vicente V,Rivera J

更新日期：2010-03-01 00:00:00

abstract：:The Goodeniaceae family contributes some of the more spectacular wildflowers found on the Australian continent. The bright and vibrant colours that characterise members of the family has attracted much horticultural interest. A number of species have traditionally been used for medicinal purposes by indigenous communi...

journal_title：Fitoterapia

authors： Ghisalberti EL

更新日期：2004-07-01 00:00:00

abstract：:Investigation of the dichloromethane extract of the stem of Filicium decipiens yielded a new natural product, 24-norneohopa-4(23),22(29)-diene-3beta,6beta,7beta-triol 7-caffeate (1). ...

journal_title：Fitoterapia

authors： Jayasinghe UL,Bandara AG,Hara N,Fujimoto Y

更新日期：2001-11-01 00:00:00

abstract：:Linarin (acacetin-7-O-beta-d-rutinoside) from the flower extract of Mentha arvensis showed selective dose dependent inhibitory effect on acetylcholinesterase. ...

journal_title：Fitoterapia

authors： Oinonen PP,Jokela JK,Hatakka AI,Vuorela PM

更新日期：2006-09-01 00:00:00

abstract：:The first chemical examination of roots of the traditionally used medicinal plant Talinum triangulare (Portulacaceae) from Nigeria led to the isolation of two new C-methylated flavonoids, 5,6-dimethoxy-7-hydroxy-8-methyl-flavone (1), 5,6-dimethoxy-8-methyl-2-phenyl-7H-1-benzopyran-7-one (2), and one new α-pyrone deriv...

journal_title：Fitoterapia

authors： Umeokoli BO,Muharini R,Okoye FB,Ajiwe VI,Akpuaka MU,Lin W,Liu Z,Proksch P

更新日期：2016-03-01 00:00:00

abstract：:Seventy-six plant species from 46 botanical families, traditionally used to treat intestinal diseases in Mbalmayo region are recorded. The local names and the way the plants are used are indicated. ...

journal_title：Fitoterapia

authors： Noumi E,Yomi A

更新日期：2001-03-01 00:00:00

abstract：:An ethnobotanical and ethnopharmacognostic survey has been carried out in one of the most isolated mountainous area in Europe: the village of Lepushe and its surrounding territory, in the Northern Albanian Alps. Approximately 70 botanical taxa and 160 preparations, mainly derived from plants, but also derived from ani...

journal_title：Fitoterapia

authors： Pieroni A,Dibra B,Grishaj G,Grishaj I,Gjon Maçai S

更新日期：2005-06-01 00:00:00

abstract：:A new C(18)-phytosphingosine ceramide containing non-hydroxy fatty acid, armillaramide (1), has been isolated together with ergosterol peroxide from the fruiting bodies of the basidiomycete Armillaria mellea. Its structure was established as (2S,3S,4R)-2-hexadecanoylamino-octadecane-1,3,4-triol by spectroscopic and ch...

journal_title：Fitoterapia

authors： Gao JM,Yang X,Wang CY,Liu JK

更新日期：2001-12-01 00:00:00

abstract：:Two ethanolic propolis extracts (EPE) with and without the caffeic acid phenethyl ester (CAPE), CAPE and galangin (major components of propolis) were investigated for anti-inflammatory activity in rats using carrageenin foot oedema, carrageenin pleurisy and adjuvant arthritis. In our experiments, EPE with CAPE and CAP...

journal_title：Fitoterapia

authors： Borrelli F,Maffia P,Pinto L,Ianaro A,Russo A,Capasso F,Ialenti A

更新日期：2002-11-01 00:00:00