Antibacterial activity of plant extracts from Brazilian southeast region.

abstract：:Seven new lignan glycosides (1-3, 8-10, and 14) and 17 known compounds were isolated from the branches of Alangium kurzii Craib var. laxifolium. Their structures were established by spectroscopic analysis and circular dichroism (CD) and X-ray analysis. The isolated compounds were evaluated for their antibacterial acti...

journal_title：Fitoterapia

authors： Ren J,Xie YG,Huang YY,Zhu SL,Yan SK,Jin HZ,Zhang WD

更新日期：2017-09-01 00:00:00

abstract：:Rheum palmatum Linn has been widely applied in the clinical treatment of diabetes mellitus. It has been found that emodin as the major bioactive component of R. palmatum L exhibits the competency to activate peroxisomal proliferator-activated receptor-gamma (PPARgamma) in vitro. So the aim of this study was to evaluat...

journal_title：Fitoterapia

authors： Xue J,Ding W,Liu Y

更新日期：2010-04-01 00:00:00

abstract：:Three new furoquinoline alkaloids, leptanoines A-C (1-3) along with three known compounds (4-6) were isolated from the leaves of Evodia lepta. Their structures were identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. In addition, all isolated compounds ...

journal_title：Fitoterapia

authors： Sichaem J,Jirasirichote A,Sapasuntikul K,Khumkratok S,Sawasdee P,Do TM,Tip-pyang S

更新日期：2014-01-01 00:00:00

abstract：:Two new ent-kaurene diterpenoids, 15α-acetoxyl-6,11α-epoxy-6α-hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7-olide (1), 15α-hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide (2), together with ten known compounds (5-14) were isolated from the leaves of Isodon rubescens. Their structures were elucidated mainly by ...

journal_title：Fitoterapia

authors： Xie RJ,Yan FL,Hai GF,Hou RJ,Ding MM,Bai YX

更新日期：2011-06-01 00:00:00

abstract：:Pocahemiketals A and B (1 and 2), two novel hemiketal sesquiterpenoids with unprecedented skeletons, were isolated from the essential oil of the aerial parts of Pogostemon cablin. In addition to a bicyclo[3.2.1]-carbon core, 1 and 2 possessed a hemiketal α,β-unsaturated-γ-lactone moiety. Their structures were determin...

journal_title：Fitoterapia

authors： Zhu H,Zhou QM,Peng C,Chen MH,Li XN,Lin DS,Xiong L

更新日期：2017-07-01 00:00:00

abstract：:The phytochemical profile, antioxidant activity and α-glucosidase inhibitory activity of Hypericum scruglii Bacchetta, Brullo et Salmeri and Hypericum hircinum L. were analyzed and compared to those of the best-known Hypericum perforatum L. Samples were prepared using three different extraction methods (maceration in ...

journal_title：Fitoterapia

authors： Mandrone M,Scognamiglio M,Fiorentino A,Sanna C,Cornioli L,Antognoni F,Bonvicini F,Poli F

更新日期：2017-07-01 00:00:00

abstract：:The gastrointestinal activity of hydroalcoholic extract (HE) of Salvia officinalis was evaluated in a model of ethanol-induced gastric lesion. HE showed excellent activity, with ID(50) 84.0 (54.8-128.9) mg/kg. The acetic acid-induced ulcer and the total acidity of the gastric secretion were also reduced by HE, and, in...

journal_title：Fitoterapia

authors： Mayer B,Baggio CH,Freitas CS,dos Santos AC,Twardowschy A,Horst H,Pizzolatti MG,Micke GA,Heller M,dos Santos EP,Otuki MF,Marques MC

更新日期：2009-10-01 00:00:00

abstract：:The inhibitory activity of alpha-amylase and the phytochemical composition of Cedrus libani essential oils obtained from wood, leaves and cones were investigated. The C. libani woods oil exhibit an IC(50) value of 0.14 mg/ml, whereas the leaves and cones oils were devoid of any significant activity. ...

journal_title：Fitoterapia

authors： Loizzo MR,Saab AM,Statti GA,Menichini F

更新日期：2007-06-01 00:00:00

abstract：:Four pairs of racemic phenylpropanoids (1a/1b-4a/4b), including five new compounds (1a/1b, 2a, 3a, and 4a) were obtained from the root barks of Ailanthus altissima (Mill.) Swingle. Their structures were determined by comprehensive spectroscopic analyses. The absolute configurations of the enantiomers were determined b...

journal_title：Fitoterapia

authors： Yan ZY,Chen JJ,Duan ZK,Yao GD,Lin B,Wang XB,Huang XX,Song SJ

更新日期：2018-10-01 00:00:00

abstract：:The antioxidant effect of aqueous methanolic herb extracts of Serratula coronata, S. wolffii and S. tinctoria was investigated using both enzyme-dependent and enzyme-independent systems. The extracts displayed concentration-dependent inhibition of lipid peroxidation. Flavonoids and ecdysteroids present in the extracts...

journal_title：Fitoterapia

authors： Báthori M,Zupkó I,Hunyadi A,Gácsné-Baitz E,Dinya Z,Forgó P

更新日期：2004-03-01 00:00:00

abstract：:The purpose of this study is to elucidate the bioactive components responsible for the the α-glucosidase inhibitory activity detected in the EtOAc extract of the mushroom Hydnellum concrescens. Two new p-terphenyl derivatives, concrescenins A (1) and B (2), in along with six known compounds thelephantins L (3), I (4),...

journal_title：Fitoterapia

authors： Wang SM,Han JJ,Ma K,Jin T,Bao L,Pei YF,Liu HW

更新日期：2014-10-01 00:00:00

abstract：:Rats treated with 100 mg /kg/day of the Catharanthus roseus ethanol extract had high rate of wound contraction significantly decreased epithelization period, significant increase in dry weight and hydroxyproline content of the granulation tissue when compared with the controls. Wound contraction together with increase...

journal_title：Fitoterapia

authors： Nayak BS,Anderson M,Pinto Pereira LM

更新日期：2007-12-01 00:00:00

abstract：:In our previous study, RAPD (Random Amplified Polymorphic DNA) analysis revealed species-specific markers for three medicinal Echinacea species (Asteraceae): E. angustifolia DC., E. pallida (Nutt.) Nutt. and E. purpurea (L.) Moench. In the present work, we have converted a RAPD marker (750 bp) for E. purpurea into a S...

journal_title：Fitoterapia

authors： Adinolfi B,Chicca A,Martinotti E,Breschi MC,Nieri P

更新日期：2007-01-01 00:00:00

abstract：:Malaria is one of the most devastating infectious diseases in the developing world. Until now, only one candidate malaria vaccine RTS,S/AS01 has shown modest protection in phase 3 trial in African infants. Hence the treatment of malaria still depends on the current chemotherapeutic drugs. Considering the resistance of...

journal_title：Fitoterapia

authors： Jin H,Xu Z,Cui K,Zhang T,Lu W,Huang J

更新日期：2014-04-01 00:00:00

abstract：:The objective of this study was to evaluate potential hepatoprotective capabilities of quercetin in relation to its modulation of the HO-1 and NOS-2 activities in an experimental model of fulminant liver failure. Liver insult was induced by in vivo administration of D-galactosamine (d-GalN, 400 mg/kg, i.p.) and lipopo...

journal_title：Fitoterapia

authors： Lekić N,Canová NK,Hořínek A,Farghali H

更新日期：2013-06-01 00:00:00

abstract：:The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...

journal_title：Fitoterapia

authors： Chen TL,Zhang YB,Xu W,Kang TG,Yang XW

更新日期：2014-03-01 00:00:00

abstract：:The ethanolic extracts of Lawsonia inermis leaves, Holarrhena antidysenterica bark, Swertia chirata whole plant and Mangifera indica bark were tested (in-vitro) for alpha-glucosidase inhibitory activity. M. indica extract was found to be the most potent, with an IC(50) value of 314 microg/ml. ...

journal_title：Fitoterapia

authors： Prashanth D,Amit A,Samiulla DS,Asha MK,Padmaja R

更新日期：2001-08-01 00:00:00

abstract：:The antituberculosis activity of 14 natural azorellane and mulinane diterpenoids isolated from Azorella compacta, Azorella madreporica, Mulinum crassifolium, and Laretia acaulis, together with eight semisynthetic derivatives, was evaluated against two Mycobacterium tuberculosis strains. The natural azorellanes azorell...

journal_title：Fitoterapia

authors： Molina-Salinas GM,Bórquez J,Ardiles A,Said-Fernández S,Loyola LA,San-Martín A,González-Collado I,Peña-Rodríguez LM

更新日期：2010-01-01 00:00:00

abstract：:The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml a...

journal_title：Fitoterapia

authors： Psotová J,Chlopcíková S,Miketová P,Simánek V

更新日期：2005-09-01 00:00:00

abstract：:Five new lanostane triterpenoids, ganoderic acid XL1 (1), ganoderic acid XL2 (2), 20-hydroxy-ganoderic acid AM1 (3), ganoderenic acid AM1 (4) and ganoderesin C (5), together with five known triterpenoids (6-10) were isolated from the fruiting bodies of Ganoderma theaecolum. Chemical structures were elucidated on the b...

journal_title：Fitoterapia

authors： Liu LY,Chen H,Liu C,Wang HQ,Kang J,Li Y,Chen RY

更新日期：2014-10-01 00:00:00

abstract：:A botanical natural product, AkseBio2, was evaluated for its larvicidal effect against Culex pipiens under laboratory conditions. The product exhibited strong larvicidal activity and caused >90% mortalities in both the young (first-second) and the older (third-fourth) larval stages of the species at 24 h at the doses ...

journal_title：Fitoterapia

authors： Cetin H,Erler F,Yanikoglu A

更新日期：2004-12-01 00:00:00

abstract：:Successive petroleum ether, dichloromethane and methanol extracts of Ajuga remota aerial parts were tested in vitro for their antifungal activity. The petroleum ether fraction was found to be the most effective against the tested pathogens. ...

journal_title：Fitoterapia

authors： Kariba RM

更新日期：2001-02-01 00:00:00

abstract：:From the roots of Smilax bockii a new compound, 7-hydroxymethyl-1, 4, 5-trihydroxynaphthalene-4-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranoside, was isolated. The structure of the new compound was elucidated on the basis of spectroscopic methods. ...

journal_title：Fitoterapia

authors： Li X,Xu J,Zhang P,Li N,Meng DL

更新日期：2008-09-01 00:00:00

abstract：:The flavonoid baicalein has been demonstrated to be an activator of the transcription factor Nrf2 in mammalian cell lines. We show that it further modulates the Nrf2 homolog SKN-1 in Caenorhabditis elegans and by this pathway mediates beneficial effects in the nematode: baicalein enhances the resistance of C. elegans ...

journal_title：Fitoterapia

authors： Havermann S,Humpf HU,Wätjen W

更新日期：2016-09-01 00:00:00

abstract：:The furanocoumarin imperatorin has been reported to have hypotensive effect, and we have investigated its activity on myocardial hypertrophy. Imperatorin displayed similar chromatographic retention peak to verapamil in the model of cardiac muscle/cell membrane chromatography, and could reduce in a concentration-depend...

journal_title：Fitoterapia

authors： Zhang Y,Cao Y,Zhan Y,Duan H,He L

更新日期：2010-12-01 00:00:00

abstract：:Oral treatment with the water extracts of Scoparia dulcis whole aerial parts, at doses of 50, 100 and 200 mg/kg, dose dependently inhibited the indomethacin-induced gastric damages in rats. ...

journal_title：Fitoterapia

authors： Babincová M,Schronerová K,Sourivong P

更新日期：2008-12-01 00:00:00

abstract：:The alkaloidic fraction of the methanol extract of Peganum harmala seeds was tested in vitro on three tumoral cell-lines: UCP-Med and Med-mek carcinoma, and UCP-Med sarcoma. Proliferation was significantly reduced at all tested concentrations (20-120 micrograms/ml) during the first 24 h of contact. A cell lysis effect...

journal_title：Fitoterapia

authors： Lamchouri F,Settaf A,Cherrah Y,Hassar M,Zemzami M,Atif N,Nadori EB,Zaid A,Lyoussi B

更新日期：2000-02-01 00:00:00

abstract：:Two new alkaloids, named stenine A (1) and stenine B (2), along with the known compounds neostenine (3), stenine (4) and neotuberostemonine (5), were isolated from the roots of Stemona sessilifolia. Their structures were elucidated by 1D- and 2D-NMR spectra and X-ray single-crystal diffraction experiment. Anti-acetylc...

journal_title：Fitoterapia

authors： Lai DH,Yang ZD,Xue WW,Sheng J,Shi Y,Yao XJ

更新日期：2013-09-01 00:00:00

abstract：:To determine whether the two major compounds of Erythrina lysistemon are active principles accounting for Erythrina estrogenic effects, we used a postmenopause-like model of ovariectomized Wistar rats to evaluate their effects on some menopausal problems. Ovariectomized rats were orally treated either with compound 1 ...

journal_title：Fitoterapia

authors： Mvondo MA,Njamen D,Fomum ST,Wandji J,Vollmer G

更新日期：2011-10-01 00:00:00

abstract：:Five new guaiane-type sesquiterpenoids were obtained from the roots of Daphne genkwa. Their gross structures were established by extensive spectroscopic analyses. Attempts on the assignment of the relative configurations were unsuccessful when based on the NOESY correlations. Therefore, NMR chemical shift calculations...

journal_title：Fitoterapia

authors： Wang J,Ren Q,Zhang YY,Guo R,Lin B,Huang XX,Song SJ

更新日期：2019-10-01 00:00:00