Antibacterial activity of plant extracts from Brazilian southeast region.


:A screening was conducted with 26 plants collected in the Brazilian southeast region, to identify plant extracts with antibacterial properties against Aeromonas hydrophila, Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus. Initially, the agar diffusion method was employed. Then, those extracts presenting activity were submitted to a broth microdilution assay to determine the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC). It was observed that 13 of the tested extracts showed antibacterial activity. The best results were obtained with those from Lantana lilacina and Phyllanthus tenellus.






Oliveira DF,Pereira AC,Figueiredo HC,Carvalho DA,Silva G,Nunes AS,Alves DS,Carvalho HW




Has Abstract


2007-02-01 00:00:00














  • Two novel eremophylane acetophenone conjugates from Colletotrichum gloeosporioides, an endophytic fungus in Salvia miltiorrhiza.

    abstract::Two novel eremophylane acetophenone conjugates, colletotricholides A (1) and B (2), were isolated from the solid fermentation cultures of an endophytic fungus Colletotrichum gloeosporioides XL1200 isolated from the aerial parts of Salvia miltiorrhiza. The chemical structures of 1-2 were characterized by extensive spec...


    pub_type: 杂志文章


    authors: Zhao WT,Liu QP,Chen HY,Zhao W,Gao Y,Yang XL

    更新日期:2020-03-01 00:00:00

  • Subnudatones A and B, new trans-decalin polyketides from the cultured lichen mycobionts of Pseudopyrenula subnudata.

    abstract::Chemical investigation of the cultured polyspore-derived mycobionts of a Pseudopyrenula subnudata lichen led to the isolation of two new compounds, subnudatones A and B (1 and 2), together with four known compounds, 1-(2-hydroxy-1,2,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)ethanone (3), libertalide C (4)...


    pub_type: 杂志文章


    authors: Duong TH,Nguyen HH,Le TT,Tran TN,Sichaem J,Nguyen TT,Nguyen TP,Mai DT,Nguyen HH,Le HD

    更新日期:2020-04-01 00:00:00

  • Effect of nagilactone E on cell morphology and glucan biosynthesis in budding yeast Saccharomyces cerevisiae.

    abstract::Nagilactones are norditerpene dilactones isolated from the root bark of Podocarpus nagi. Although nagilactone E has been reported to show antifungal activities, its activity is weaker than that of antifungals on the market. Nagilactone E enhances the antifungal activity of phenylpropanoids such as anethole and isosafr...


    pub_type: 杂志文章


    authors: Hayashi K,Yamaguchi Y,Ogita A,Tanaka T,Kubo I,Fujita KI

    更新日期:2018-07-01 00:00:00

  • Millaurine A, a new guanidine alkaloid from seeds of Millettia laurentii.

    abstract::A new guanidine alkaloid, millaurine A (1), was isolated from the methanol extract of the seeds of Millettia laurentii. The structure of the new compound was elucidated on the basis of spectral analysis. ...


    pub_type: 杂志文章


    authors: Ngamga D,Fanso Free SN,Tane P,Fomum ZT

    更新日期:2007-04-01 00:00:00

  • Atranones from Stachybotrys chartarum and their antitumor activities in MG-63 human osteosarcoma cells.

    abstract::Two new atranones T and U (1 and 2), and three known analogues atranone B (3), atranone Q (4), and stachatranone C (5) were isolated from the toxigenic fungus Stachybotrys chartarum. Their structures and absolute configurations were elucidated by spectroscopic data and calculated ECD analyses. The cytotoxicities of al...


    pub_type: 杂志文章


    authors: Qin YD,Fang FM,Zhou JJ,Wang RB,Xu SX,Li LH,Zhang HL

    更新日期:2020-10-01 00:00:00

  • The antiadhesive activity of cranberry phytocomplex studied by metabolomics: Intestinal PAC-A metabolites but not intact PAC-A are identified as markers in active urines against uropathogenic Escherichia coli.

    abstract::Cranberry procyanidins and quercetin derivatives are considered possible active compounds against urinary tract infections (UTIs). In this paper a small group (n=6) of healthy subjects consumed a product containing 360mg of cranberry extract (42.6% w/w of PAC-A and 14.6% w/w of PAC-B) and 200mg of quercetin. Urine sam...


    pub_type: 杂志文章


    authors: Peron G,Sut S,Pellizzaro A,Brun P,Voinovich D,Castagliuolo I,Dall'Acqua S

    更新日期:2017-10-01 00:00:00

  • New tricyclic prezizaane sesquiterpenoids from agarwood.

    abstract::Ten new tricyclic prezizaane types sesquiterpenoids (1-10) were isolated from ethyl ether extract of agarwood originated from Aquilaria sp. Their structures were unambiguously elucidated on the basis of 1D and 2D NMR spectra as well as by HRESIMS data. The absolute configuration of the new prezizaenes 1, 2 and 4 was d...


    pub_type: 杂志文章


    authors: Yang YL,Li W,Wang H,Yang L,Yuan JZ,Cai CH,Chen HQ,Dong WH,Ding XP,Jiang B,Mándi A,Kurtán T,Mei WL,Dai HF

    更新日期:2019-10-01 00:00:00

  • Hirtellina lobelii DC. essential oil, its constituents, its combination with antimicrobial drugs and its mode of action.

    abstract::With the goal of unravelling antimicrobial agents and mixtures inspired by plant defences, we investigated the antibacterial and antifungal efficacy of Hirtellina lobelii DC. essential oil (EO), both alone and in combination with antimicrobial drugs. Hirtellina lobelii DC. EO was analysed by GC, GC-MS and partial frac...


    pub_type: 杂志文章


    authors: Khoury M,El Beyrouthy M,Ouaini N,Eparvier V,Stien D

    更新日期:2019-03-01 00:00:00

  • Lycocasuarines I-Q, new Lycopodium alkaloids isolated from Lycopodiastrum casuarinoides.

    abstract::Lycocasuarines I-Q (1-9), nine new lycodine-type Lycopodium alkaloids were isolated from the aerial parts of Lycopodiastrum casuarinoides (Spring) Holub ex R.D.Dixit. Their structures were unambiguously determined via extensive spectroscopic analyses, including HRESIMS, NMR, and electronic circular dichroism (ECD). Th...


    pub_type: 杂志文章


    authors: Zhu XL,Wang LL,Shi ZH,Xia D,Zhou ZB,Pan K

    更新日期:2019-04-01 00:00:00

  • Furanocoumarins-imperatorin inhibits myocardial hypertrophy both in vitro and in vivo.

    abstract::The furanocoumarin imperatorin has been reported to have hypotensive effect, and we have investigated its activity on myocardial hypertrophy. Imperatorin displayed similar chromatographic retention peak to verapamil in the model of cardiac muscle/cell membrane chromatography, and could reduce in a concentration-depend...


    pub_type: 杂志文章


    authors: Zhang Y,Cao Y,Zhan Y,Duan H,He L

    更新日期:2010-12-01 00:00:00

  • Latex proteins from the plant Calotropis procera are partially digested upon in vitro enzymatic action and are not immunologically detected in fecal material.

    abstract::Soluble proteins from the latex of Calotropis procera (LP) were investigated in vitro and in vivo for digestibility as the latex has previously been shown to produce considerable toxic effects on animals. The latex is also an important biologically active compound that displays antiinflammatory and antidiarrhea proper...


    pub_type: 杂志文章


    authors: Ramos MV,Aguiar VC,da Silva Xavier AA,Lima MW,Bandeira GP,Etchells JP,Nogueira NA,Alencar NM

    更新日期:2006-06-01 00:00:00

  • Isolation, characterization and acetylcholinesterase inhibitory activity of alkaloids from roots of Stemona sessilifolia.

    abstract::Two new alkaloids, named stenine A (1) and stenine B (2), along with the known compounds neostenine (3), stenine (4) and neotuberostemonine (5), were isolated from the roots of Stemona sessilifolia. Their structures were elucidated by 1D- and 2D-NMR spectra and X-ray single-crystal diffraction experiment. Anti-acetylc...


    pub_type: 杂志文章


    authors: Lai DH,Yang ZD,Xue WW,Sheng J,Shi Y,Yao XJ

    更新日期:2013-09-01 00:00:00

  • Alkaloids from Coptis chinensis root promote glucose uptake in C2C12 myotubes.

    abstract::The root of Coptis chinensis Franch. (COCH) is regularly used for medicinal purposes, and has been prescribed alone or in combination with other traditional herbs for the treatment of diabetes. To investigate the effects of COCH on glucose utilization by skeletal muscles, we prepared an ethanol extract of COCH root (C...


    pub_type: 杂志文章


    authors: Yang TC,Chao HF,Shi LS,Chang TC,Lin HC,Chang WL

    更新日期:2014-03-01 00:00:00

  • Bioactive phthalides from Ligusticum sinense Oliv cv. Chaxiong.

    abstract::Five new phthalides (1-4, 6), two new natural products (5, 7) and five known phthalides (8-12) were isolated from the aerial parts of Ligusticum sinense Oliv cv. Chaxiong. Their structures were elucidated by HR-ESI-MS, UV, IR, 1D and 2D NMR (HSQC, HMBC, (1)H-(1)H COSY, NOESY) methods. The absolute configurations were ...


    pub_type: 杂志文章


    authors: Wei Q,Yang J,Ren J,Wang A,Ji T,Su Y

    更新日期:2014-03-01 00:00:00

  • Inhibitory effects of Zuo-Jin-Wan and its alkaloidal ingredients on activator protein 1, nuclear factor-κB, and cellular transformation in HepG2 cells.

    abstract::Zuo-Jin-Wan (ZJW) has been used to treat hepatocellular carcinoma in Asia. This study was to determine whether ZJW and its components blocked activator protein 1 (AP-1) and nuclear factor-κB (NF-κB) activities as well as tumor promotion in hepatoblastoma HepG2 cells. ZJW and its components, Coptis chinensis and Evodia...


    pub_type: 杂志文章


    authors: Chao DC,Lin LJ,Kao ST,Huang HC,Chang CS,Liang JA,Wu SL,Hsiang CY,Ho TY

    更新日期:2011-06-01 00:00:00

  • Diterpenoids from the seeds of Euphorbia lathyris and their effects on microglial nitric oxide production.

    abstract::Four new lathyrane-type diterpenoids (1-4) and a novel macrocyclic diterpenoid (5) featuring a 5/7/7/4-fused ring system, together with seventeen known ones (6-22), were isolated from the seeds of Euphorbia lathyris. Their structures were elucidated by extensive spectroscopic analyses and single crystal X-ray crystall...


    pub_type: 杂志文章


    authors: Zuo Q,Mu HY,Gong Q,Ding X,Wang W,Zhang HY,Zhao WM

    更新日期:2021-01-26 00:00:00

  • Astershionones A-F, six new anti-HBV shionane-type triterpenes from Aster tataricus.

    abstract::Six new shionane-type triterpenes, astershionones A-F (1-6), were obtained from the roots and rhizomes of Aster tataricus. Their structures were elucidated on the basis of spectroscopic data, mainly NMR and MS data. The absolute configuration of 1 was determined by single crystal X-ray diffraction analysis and CD anal...


    pub_type: 杂志文章


    authors: Zhou WB,Zeng GZ,Xu HM,He WJ,Zhang YM,Tan NH

    更新日期:2014-03-01 00:00:00

  • An in vivo analysis of the therapeutic and synergistic properties of Chinese medicinal formula Yin-Chen-Hao-Tang based on its active constituents.

    abstract::6,7-Dimethylesculetin (D), geniposide (G) and rhein (R) are the three major active ingredients of Yin-Chen-Hao-Tang (YCHT), a famous Chinese herbal formula, which has been shown to be clinically effective for treating hepatic injury (HI) syndrome. The present study was conducted to investigate the therapeutic and syne...


    pub_type: 杂志文章


    authors: Zhang A,Sun H,Yuan Y,Sun W,Jiao G,Wang X

    更新日期:2011-12-01 00:00:00

  • Evaluation of the anti-microbial and anti-inflammatory activities of the medicinal plants Dodonaea viscosa, Rumex nervosus and Rumex abyssinicus.

    abstract::The crude extracts of the leaves of Dodonaea viscosa and Rumex nervosus as well as of the root of Rumex abyssinicus were tested for anti-microbial and anti-inflammatory activities. It was observed that the three plants possess antibacterial activity against Streptococcus pyogenes and Staphylococcus aureus and strong a...


    pub_type: 杂志文章


    authors: Getie M,Gebre-Mariam T,Rietz R,Höhne C,Huschka C,Schmidtke M,Abate A,Neubert RH

    更新日期:2003-02-01 00:00:00

  • New triterpenoids and PTP1B inhibitory constituents of Pseudolarix amabilis.

    abstract::Six new triterpenoids, pseudolarins A-F (1-6), were isolated from the twigs of Pseudolarix amabilis, together with four known triterpenoids (7-10) and five known diterpenoids (11-15). Their structures were determined by extensive spectroscopic analysis, and the absolute configuration of 1 was assigned by single-crysta...


    pub_type: 杂志文章


    authors: Lei C,Huang QH,Zhao T,Wang PP,Li JY,Li J,Hou AJ

    更新日期:2019-11-01 00:00:00

  • Four new quassinoids from the roots of Eurycoma longifolia Jack.

    abstract::Seven compounds were isolated from the roots of Eurycoma longifolia, and characterized by comprehensive analysis of 1D and 2D NMR experiments along with single crystal X-ray diffraction. Among them, four new quassinoids were identified and three of them were diastereomers for each other. Compounds 1-7 were evaluated f...


    pub_type: 杂志文章


    authors: Meng D,Li X,Han L,Zhang L,An W,Li X

    更新日期:2014-01-01 00:00:00

  • Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies.

    abstract::Bergamot juice produces hypolipemic activity in rats though the mechanism remains unclear. Here we investigated on the effect of bergamot extract (BPF) in diet-induced hyperlipemia in Wistar rats and in 237 patients suffering from hyperlipemia either associated or not with hyperglycaemia. BPF, given orally for 30 days...


    pub_type: 杂志文章,随机对照试验


    authors: Mollace V,Sacco I,Janda E,Malara C,Ventrice D,Colica C,Visalli V,Muscoli S,Ragusa S,Muscoli C,Rotiroti D,Romeo F

    更新日期:2011-04-01 00:00:00

  • Transcriptome analysis of Aconitum carmichaelii and exploration of the salsolinol biosynthetic pathway.

    abstract::Aconitum carmichaelii has been used in traditional Chinese medicine for treating various diseases for several thousand years. Based on the biosynthetic pathway of some alkaloids such as C19-diterpenoid alkaloids and obvious differences in alkaloid content between leaves of two A. carmichaelii varieties has been report...


    pub_type: 杂志文章


    authors: Yang Y,Hu P,Zhou X,Wu P,Si X,Lu B,Zhu Y,Xia Y

    更新日期:2020-01-01 00:00:00

  • Biotransformation of isoimperatorin by rat liver microsomes and its quantification by LC-MS/MS method.

    abstract::The aim of the present research was to establish a comprehensive strategy to identify the metabolites of isoimperatorin after biotransformation with rat liver microsomes in vitro, and further describe metabolic kinetic characteristics of isoimperatorin and its main metabolites. Utilizing liquid chromatography with tim...


    pub_type: 杂志文章


    authors: Chen TL,Zhang YB,Xu W,Kang TG,Yang XW

    更新日期:2014-03-01 00:00:00

  • A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.

    abstract::The Src-homology 2 domain-containing phosphatase 2 (SHP2), encoded by PTPN11, has been reported oncogenic tyrosine phosphatase associated with various tumors and played critical roles in many cell signaling events. Targeting SHP2 by small molecules may be a promising way for cancer therapy. Herein, a new abietane dite...


    pub_type: 杂志文章


    authors: Liu DM,Cao ZX,Yan HL,Li W,Yang F,Zhao WJ,Diao QC,Tan YZ

    更新日期:2020-03-01 00:00:00

  • A new arylnaphthalene lignan from Knema furfuracea.

    abstract::A new arylnaphthalene lignan, named furfuracin, was isolated from the leaves of Knema furfuracea (Myristicaceae), whereas 7 known compounds including (+)-trans-1,2-dihydrodehydroguaiaretic acid, fragransin A(2), biochanin A, gingkolic acid, anarcardic acid, 2-hydroxy-6-(12-phenyldodecyl)-benzoic acid and 2-hydroxy-6-(...


    pub_type: 杂志文章


    authors: Rangkaew N,Suttisri R,Moriyasu M,Kawanishi K

    更新日期:2009-09-01 00:00:00

  • High performance liquid chromatographic analysis and anticancer potential of Oplopanax horridus: comparison of stem and berry extracts.

    abstract::Oplopanax horridus or devil's club is a herbal medicine distributed in North America. The constituents and pharmacological activities of O. horridus (OPH) are largely unknown. In this study, we assayed OPH stem and berry extracts using high performance liquid chromatography (HPLC). The anticancer potentials of extract...


    pub_type: 杂志文章


    authors: Wang CZ,Aung HH,Mehendale SR,Shoyama Y,Yuan CS

    更新日期:2010-03-01 00:00:00

  • Caesalpinone A, a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, from the pods of Caesalpinia spinosa Kuntze.

    abstract::Caesalpinone A (1), a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, along with ten known sesquiterpenoids (2-11) were isolated from the pods of Caesalpinia spinosa Kuntze (Tara). The structure of caesalpinone A was elucidated based on its 1D and 2D NMR spectra. The absolute configurati...


    pub_type: 杂志文章


    authors: Mu W,Tang H,Li Y,He D,Ma R,Wang L

    更新日期:2016-07-01 00:00:00

  • Five novel naphthylisoquinoline alkaloids with growth inhibitory activities against human leukemia cells HL-60, K562 and U937 from stems and leaves of Ancistrocladus tectorius.

    abstract::Two new 7,6'-coupled naphthylisoquinolines, namely ancistrotectorines A (1) and B (2), two new 5,3'-coupled naphthylisoquinolines, namely ancistrotectorines C (3) and D (4), and one new 7,8-coupled naphthylisoquinoline, namely ancistrotectorine E (5), together with 9 known naphthylisoquinoline alkaloids, hamatine (6),...


    pub_type: 杂志文章


    authors: Jiang C,Li ZL,Gong P,Kang SL,Liu MS,Pei YH,Jing YK,Hua HM

    更新日期:2013-12-01 00:00:00

  • Phenylpropanoids and neolignans from Smilax trinervula.

    abstract::A new phenylpropanoid glucoside and two new neolignans, namely (1S, 2R)-1-(3, 4, 5-trimethoxyphenyl)-3-(β-d-glucopyranosyloxy)-1, 2, 3-propanetriol (1), and (7R, 8R)-4, 7, 9, 9'-tetrahydroxy-3, 5, 3', 5'-tetramethoxy-8-4'-oxyneolignan 4-O-β-d-glucopyranoside (2) and 3', 9, 9'-trihydroxy-3, 5-dimethoxy-8-O-4'-neolignan...


    pub_type: 杂志文章


    authors: Shu J,Liang F,Liang J,Liang Y,Li F,Shao F,Liu R,Huang H

    更新日期:2015-07-01 00:00:00