In vitro cell-toxicity of Peganum harmala alkaloids on cancerous cell-lines.

Abstract:

:The alkaloidic fraction of the methanol extract of Peganum harmala seeds was tested in vitro on three tumoral cell-lines: UCP-Med and Med-mek carcinoma, and UCP-Med sarcoma. Proliferation was significantly reduced at all tested concentrations (20-120 micrograms/ml) during the first 24 h of contact. A cell lysis effect occurred after 24 h and increased thereafter to complete cell death within 48-72 h, depending on tested concentration.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Lamchouri F,Settaf A,Cherrah Y,Hassar M,Zemzami M,Atif N,Nadori EB,Zaid A,Lyoussi B

doi

10.1016/s0367-326x(99)00117-3

keywords:

subject

Has Abstract

pub_date

2000-02-01 00:00:00

pages

50-4

issue

1

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(99)00117-3

journal_volume

71

pub_type

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