Abstract:
:Two new naphthofuranone derivatives, 11-hydroxy-2-O-methylhibiscolactone A (1) and O-methylhibiscone D (2), have been isolated from the stems of Pachira aquatica, together with 18 known compounds (3-20). The structures of two new compounds were determined through spectroscopic and MS analyses. Among the isolated compounds, 11-hydroxy-2-O-methylhibiscolactone A (1), isohemigossylic acid lactone-7-methyl ether (4), gmelofuran (6), and 5-hydroxyauranetin (8) exhibited inhibition (IC50≤28.84μM) of superoxide anion generation by human neutrophils in response to N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP).
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Cheng LY,Liao HR,Chen LC,Wang SW,Kuo YH,Chung MI,Chen JJdoi
10.1016/j.fitote.2016.12.008subject
Has Abstractpub_date
2017-03-01 00:00:00pages
16-21eissn
0367-326Xissn
1873-6971pii
S0367-326X(16)30560-3journal_volume
117pub_type
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