Monoterpenoid indole alkaloids from Gardneria multiflora.

abstract：:Aconitum carmichaelii has been used in traditional Chinese medicine for treating various diseases for several thousand years. Based on the biosynthetic pathway of some alkaloids such as C19-diterpenoid alkaloids and obvious differences in alkaloid content between leaves of two A. carmichaelii varieties has been report...

journal_title：Fitoterapia

authors： Yang Y,Hu P,Zhou X,Wu P,Si X,Lu B,Zhu Y,Xia Y

更新日期：2020-01-01 00:00:00

abstract：:Four known flavonoids were isolated from the aerial parts of Salvia moorcroftiana. ...

journal_title：Fitoterapia

authors： Ahmad VU,Ali Z,Zahid M,Alam N,Saba N,Khan T,Qaisar M,Nisar M

更新日期：2000-02-01 00:00:00

abstract：:Isorhynchophylline is one of the major alkaloids from the Uncaria hook possessing the effects of lowered blood pressure, vasodilatation and protection against ischemia-induced neuronal damage. However, the metabolic pathway of isorhynchophylline has not been fully reported yet. In this paper, the metabolism of isorhyn...

journal_title：Fitoterapia

authors： Chen F,Qi W,Sun J,Simpkins JW,Yuan D

更新日期：2014-09-01 00:00:00

abstract：:Antioxidant activity of the ethanol extract of Erigeron breviscapus (EEEB) were studied by using neuron oxidative injury model induced by superoxide radical. EEEB at the dose of 10-140 mug/ml reduced significantly the lipid peroxidation levels and lactic dehydrogenase (LDH) release from neuron exposed to superoxide ra...

journal_title：Fitoterapia

authors： Liu H,Yang X,Ren T,Feng Y,Xu H

更新日期：2005-12-01 00:00:00

abstract：:The plants of genus Toona are well known for diverse limonoid secondary metabolites, while polyacetylenes are rarely found from Toona species. In this work, six new polyacetylenes toonasindiynes A-F (1-6) and six known analogues (7-12) were isolated from the root bark of Toona sinensis. Their structures and absolute c...

journal_title：Fitoterapia

authors： Xu WJ,Li JH,Zhou MM,Luo J,Jian KL,Tian XM,Xia YZ,Yang L,Luo J,Kong LY

更新日期：2020-10-01 00:00:00

abstract：:The effect of asiaticoside isolated from Hydrocotyle sibthorpioides (AHS) on the promotion of cognition in senescence-accelerated mice (SAMP) was evaluated. Six-month old male SAMP8 mice were orally administered 20, 40 or 80 mg/kg AHS daily for three months. SAMR1 mice were used as a "normal aging" control. The result...

journal_title：Fitoterapia

authors： Lin X,Huang R,Zhang S,Wei L,Zhuo L,Wu X,Tang A,Huang Q

更新日期：2013-06-01 00:00:00

abstract：:Five polyketides, paralactonic acids A-E (1-5) were isolated from Paraconiothyrium sp. SW-B-1, an endophytic fungus isolated from the seaweed, Chondrus ocellatus Holmes. Their structures were determined by various spectroscopic methods, predominantly by 2D NMR spectroscopic analyses. The absolute configurations of com...

journal_title：Fitoterapia

authors： Suzuki T,Ariefta NR,Koseki T,Furuno H,Kwon E,Momma H,Harneti D,Maharani R,Supratman U,Kimura KI,Shiono Y

更新日期：2019-01-01 00:00:00

abstract：:The alkaloidic fraction of the methanol extract of Peganum harmala seeds was tested in vitro on three tumoral cell-lines: UCP-Med and Med-mek carcinoma, and UCP-Med sarcoma. Proliferation was significantly reduced at all tested concentrations (20-120 micrograms/ml) during the first 24 h of contact. A cell lysis effect...

journal_title：Fitoterapia

authors： Lamchouri F,Settaf A,Cherrah Y,Hassar M,Zemzami M,Atif N,Nadori EB,Zaid A,Lyoussi B

更新日期：2000-02-01 00:00:00

abstract：:Three new sesquiterpenoids, peniterpenoids A - C (1-3), together with six known metabolites (4-9) were isolated from an entomogenous fungus Penicillium janthinellum (LB1.20090001) collected from a wheat cyst nematode. The structures of the new compounds were elucidated based on NMR and HRESIMS spectroscopic analyses. ...

journal_title：Fitoterapia

authors： Liu S,Fan W,Ren J,Wang W,Liu X,Liang Y,Wei T,Li E

更新日期：2021-01-01 00:00:00

abstract：:Caesalpinone A (1), a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, along with ten known sesquiterpenoids (2-11) were isolated from the pods of Caesalpinia spinosa Kuntze (Tara). The structure of caesalpinone A was elucidated based on its 1D and 2D NMR spectra. The absolute configurati...

journal_title：Fitoterapia

authors： Mu W,Tang H,Li Y,He D,Ma R,Wang L

更新日期：2016-07-01 00:00:00

abstract：:Callus and differentiated shoots initiated from Solanum tuberosum L. on MS media containing BA, IAA, and Kin. Glycoalkaloids are produced in callus and shoots in concentrations higher than original tubers using HPLC. Callus methanolic extract had promising anticancer activity with low IC(50) values against human carci...

journal_title：Fitoterapia

authors： Al-Ashaal HA

更新日期：2010-09-01 00:00:00

abstract：:Five new ursane-type triterpenoids, spicatusoids A-E (1, 3-6), and three known ones (2, 7, and 8), and a known oleanane-type triterpenoid (9) were isolated from the aerial parts of Clerodendranthus spicatus. Their structures were elucidated by spectroscopic methods. In particular, the structure of 3 including its abso...

journal_title：Fitoterapia

authors： Luo Y,Cheng LZ,Luo Q,Yan YM,Wang SM,Sun Q,Cheng YX

更新日期：2017-06-01 00:00:00

abstract：:Sauruchinenols A (1) and B (2), two novel monocyclic diterpenes with unique carbon skeleton, as well as two new structurally related diterpenes, sauruchinenols C (3) and D (4), were isolated from the aerial part of Saururus chinensis. Their structures were elucidated based on the analysis of spectroscopic data. A hypo...

journal_title：Fitoterapia

authors： Gao X,He J,Wu XD,Peng LY,Shao LD,Li Y,Cheng X,Zhao QS

更新日期：2017-01-01 00:00:00

abstract：:Ethanolic extract of Rungia repens aerials parts (300 and 600 mg/kg p.o) showed diuretic activity in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. ...

journal_title：Fitoterapia

authors： Basu SK,Arivukkarasu R

更新日期：2006-02-01 00:00:00

abstract：:The crude extracts of the leaves of Dodonaea viscosa and Rumex nervosus as well as of the root of Rumex abyssinicus were tested for anti-microbial and anti-inflammatory activities. It was observed that the three plants possess antibacterial activity against Streptococcus pyogenes and Staphylococcus aureus and strong a...

journal_title：Fitoterapia

authors： Getie M,Gebre-Mariam T,Rietz R,Höhne C,Huschka C,Schmidtke M,Abate A,Neubert RH

更新日期：2003-02-01 00:00:00

abstract：:Before the design of brucine-containing transdermal formulations, the pharmacodynamics and pharmacokinetics of brucine following transdermal administration should be evaluated. In this study, the effect of addition of ethanol on solubility of bruicne was investigated and 20% ethanol was added into PBS to obtain 10mg/m...

journal_title：Fitoterapia

authors： Chen J,Hu W,Qu YQ,Dong J,Gu W,Gao Y,Fang Y,Fang F,Chen ZP,Cai BC

更新日期：2013-04-01 00:00:00

abstract：:A new megastigmane sesquiterpene glucoside named chaihuxinoside A (1), and a new indole diglucoside named chaihuxinoside B (9) were isolated from the aerial parts of Bupleurum chinense DC. along with eight known compounds. Structures of two new compounds were elucidated by a combination of chemical and spectroscopic m...

journal_title：Fitoterapia

authors： Kuang H,Sun S,Yang B,Xia Y,Feng W

更新日期：2009-01-01 00:00:00

abstract：:A fast and efficient method for the isolation of the C-glucosidated xanthones mangiferin and isomangiferin from the South-African plant Cyclopia genistoides was developed for the first time. The procedure involved extraction, liquid-liquid partitioning with ethyl acetate and subsequent precipitation of mangiferin and ...

journal_title：Fitoterapia

authors： Kokotkiewicz A,Luczkiewicz M,Pawlowska J,Luczkiewicz P,Sowinski P,Witkowski J,Bryl E,Bucinski A

更新日期：2013-10-01 00:00:00

abstract：:In the last 20 years, wine phenolic compounds have received increasing interest since several epidemiological studies have suggested associations between regular consumption of moderate amount of wine and prevention of certain chronic pathologies, such as neurodegenerative diseases. This study was aimed to investigate...

journal_title：Fitoterapia

authors： Giacoppo S,Galuppo M,Lombardo GE,Ulaszewska MM,Mattivi F,Bramanti P,Mazzon E,Navarra M

更新日期：2015-06-01 00:00:00

abstract：:A review is given of how the production by plants of compounds useful as medicines or raw materials for manufacture of medicines is influenced by ultraviolet radiation, particularly by UV-B radiation (280-315 nm wavelength). The compounds considered in this review are flavonoids and other phenolics, alkaloids (especia...

journal_title：Fitoterapia

authors： Zhang WJ,Björn LO

更新日期：2009-06-01 00:00:00

abstract：:Six previously undescribed compounds, named monaxanthones A and B, monaphenol A, monathioamide A, monaprenylindole A, and monavalerolactone A, were isolated from the culture of a marine-sourced bacterium Pseudomonas sp. ZZ820R in rice medium. Their structures were elucidated based on the HRESIMS data, NMR and MS-MS sp...

journal_title：Fitoterapia

authors： Yi W,Ge ZW,Wu B,Zhang Z

更新日期：2020-06-01 00:00:00

abstract：:Bergenin, a major constituent of Caesalpinia digyna Rottler (Leguminosae) was isolated from its roots and was characterized by comparing its melting point and spectroscopic data (IR, (1)H, (13)C, Mass Spectra) with standard bergenin. Isolated bergenin was then evaluated for antidiabetic (Type 2) activity in streptozot...

journal_title：Fitoterapia

authors： Kumar R,Patel DK,Prasad SK,Laloo D,Krishnamurthy S,Hemalatha S

更新日期：2012-03-01 00:00:00

abstract：:Antimicrobial screening of Enantia polycarpa bark showed activity of the polar extracts against some microorganisms. ...

journal_title：Fitoterapia

authors： Ajali U

更新日期：2000-06-01 00:00:00

abstract：:Five new guaiane-type sesquiterpenoids were obtained from the roots of Daphne genkwa. Their gross structures were established by extensive spectroscopic analyses. Attempts on the assignment of the relative configurations were unsuccessful when based on the NOESY correlations. Therefore, NMR chemical shift calculations...

journal_title：Fitoterapia

authors： Wang J,Ren Q,Zhang YY,Guo R,Lin B,Huang XX,Song SJ

更新日期：2019-10-01 00:00:00

abstract：:The isolation of five flavonol glycosides (1-5) from the flowers of Aconitum vulparia is reported, together with the 1H- and 13C-NMR spectral data in CD(3)OD of compound 3 and 5. ...

journal_title：Fitoterapia

authors： Fico G,Braca A,Morelli I,Tomè F

更新日期：2003-06-01 00:00:00

abstract：:The phytochemical profile, antioxidant activity and α-glucosidase inhibitory activity of Hypericum scruglii Bacchetta, Brullo et Salmeri and Hypericum hircinum L. were analyzed and compared to those of the best-known Hypericum perforatum L. Samples were prepared using three different extraction methods (maceration in ...

journal_title：Fitoterapia

authors： Mandrone M,Scognamiglio M,Fiorentino A,Sanna C,Cornioli L,Antognoni F,Bonvicini F,Poli F

更新日期：2017-07-01 00:00:00

abstract：:Five new koumine-type alkaloids (1-5) along with six known ones were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated on the basis of NMR spectroscopy and electronic circular dichroism spectral analyses. The inhibitory effects of compounds 1-11 on the viabilit...

journal_title：Fitoterapia

authors： Zhang W,Zhang SY,Wang GY,Li NP,Chen MF,Gu JH,Zhang DM,Wang L,Ye WC

更新日期：2017-04-01 00:00:00

abstract：:Thirty four terpenoids, including two new cadinane-type sesquiterpenoids containing conjugated aromatic-ketone moieties, curcujinone A (1) and curcujinone B (2), were isolated from 95% ethanol extract of the root tubers of Curcuma wenyujin. Their structures were determined by spectroscopic methods, especially 2D NMR a...

journal_title：Fitoterapia

authors： Zhou CX,Zhang LS,Chen FF,Wu HS,Mo JX,Gan LS

更新日期：2017-09-01 00:00:00

abstract：:The ethanolic extract of Lawsonia inermis leaves and lawsone tested for trypsin inhibitory activity showed an IC(50) value of 64.87 and 48.6 microg/ml, respectively. ...

journal_title：Fitoterapia

authors： Yogisha S,Samiulla DS,Prashanth D,Padmaja R,Amit A

更新日期：2002-12-01 00:00:00

abstract：:Three new secoiridoid aglycones of (-)-swermusic acid A (1) and B (3), and (-)-swerimuslatone A (2), and four new secoiridoid glycosides of 6'-O-formylsweroside (4), 6'-O-formylgentiopicroside (5), 6'-O-acetylamarogentin (6) and 6'-O-acetylamaronitidin (7), along with 40 known compounds (8-47) were isolated from Swert...

journal_title：Fitoterapia

authors： Cao TW,Geng CA,Ma YB,Zhang XM,Zhou J,Tao YD,Chen JJ

更新日期：2015-04-01 00:00:00