The caper (Capparis L.): ethnopharmacology, phytochemical and pharmacological properties.

abstract：:The isolation of 14 known triterpenoids and phytosterols from the trunk bark of Maquira coriacea, and complete spectral data of a cardenolide, k-strophanthin-beta (1), are reported. ...

journal_title：Fitoterapia

authors： Mitaine-Offer AC,Sauvain M,Petermann C,Zèches-Hanrot M

更新日期：2001-11-01 00:00:00

abstract：:Ethanolic extract of Rungia repens aerials parts (300 and 600 mg/kg p.o) showed diuretic activity in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. ...

journal_title：Fitoterapia

authors： Basu SK,Arivukkarasu R

更新日期：2006-02-01 00:00:00

abstract：:Citotoxicity (inhibition of cell division in fertilized eggs of Loxechinus albus) and general toxicity (using embryos of Artemia salina) of plants belonging to the genera Senecio, Deschampsia, Alstroemeria, Anarthrophyllum, Chloraea and Geranium were investigated. ...

journal_title：Fitoterapia

authors： Cuadra P,Furrianca M,Oyarzún A,Yáñez E,Gallardo A,Fajardo V

更新日期：2005-12-01 00:00:00

abstract：:Goniothalamus macrophyllus (Blume) Hook. f. & Thoms. is a plant widely distributed in Malaysia. The aim of this study is to identify compounds from the roots of G. macrophyllus. The ground roots were extracted with aqueous methanol and partitioned sequentially with n-hexane, chloroform and butanol. Purification from t...

journal_title：Fitoterapia

authors： Abdullah N,Sahibul-Anwar H,Ideris S,Hasuda T,Hitotsuyanagi Y,Takeya K,Diederich M,Choo C

更新日期：2013-07-01 00:00:00

abstract：:Zuojinwan, which consists of Rhizoma coptidis-Evodia rutaecarpa powder (6:1,g/g), is a traditional Chinese medicine (TCM) prescription, clinically used for the treatment of gastro-intestinal disorders. This study compared the pharmacokinetics of dehydroevodiamine and coptisine, the main active ingredients in Zuojinwan...

journal_title：Fitoterapia

authors： Yan R,Wang Y,Shen W,Liu Y,Di X

更新日期：2011-12-01 00:00:00

abstract：:The ethanolic extract of Lawsonia inermis leaves and lawsone tested for trypsin inhibitory activity showed an IC(50) value of 64.87 and 48.6 microg/ml, respectively. ...

journal_title：Fitoterapia

authors： Yogisha S,Samiulla DS,Prashanth D,Padmaja R,Amit A

更新日期：2002-12-01 00:00:00

abstract：:A new sesquiterpene coumarin with a novel sesquiterpene carbon framework, Sinkiangenorin D, and ten known sesquiterpene coumarins were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds, including the relative stereochemistry, were elucidated on the basis of spectroscopic data. All of t...

journal_title：Fitoterapia

authors： Li G,Li X,Cao L,Zhang L,Shen L,Zhu J,Wang J,Si J

更新日期：2015-06-01 00:00:00

abstract：:The flavonoids are a heterogeneous group of ubiquitous plant polyphenols that abound in the human diet and are endowed with several biological activities, including immunomodulating and antioxidant activities. The bioactivity of flavonoids is tightly correlated with their chemical structure and action mechanisms, most...

journal_title：Fitoterapia

authors： Ielpo MT,Basile A,Miranda R,Moscatiello V,Nappo C,Sorbo S,Laghi E,Ricciardi MM,Ricciardi L,Vuotto ML

更新日期：2000-08-01 00:00:00

abstract：:Five new cytochalasans (1-5) were isolated from the rice fermentation of fungus Xylaria longipes, along with seven known compounds cytochalasin P (6), cytochalasin D (7), zygosporin D (8), 7-O-acetylcytochalasin D (9), cytochalasin C (10), 6,7-dihydro-7-oxo-cytochalasin C (11), and 6,7-dihydro-7-oxo-deacetylcytochalas...

journal_title：Fitoterapia

authors： Wang WX,Li ZH,He J,Feng T,Li J,Liu JK

更新日期：2019-09-01 00:00:00

abstract：:Isorhynchophylline is one of the major alkaloids from the Uncaria hook possessing the effects of lowered blood pressure, vasodilatation and protection against ischemia-induced neuronal damage. However, the metabolic pathway of isorhynchophylline has not been fully reported yet. In this paper, the metabolism of isorhyn...

journal_title：Fitoterapia

authors： Chen F,Qi W,Sun J,Simpkins JW,Yuan D

更新日期：2014-09-01 00:00:00

abstract：:Chiratone (1), a rare new chiratane type triterpenoid, together with five known triterpenoids were isolated from the rhizomes of Drynaria fortunei (Kunze) J. Sm. The structure was characterized as 20β-hydroxychiratan-22-one on the basis of extensive 1D and 2D NMR, and MS spectroscopic analyses, and was further confirm...

journal_title：Fitoterapia

authors： Liang YH,Wang W,Yu SW,Ye M,He XH,Gong NB,Lu Y,Khan IA,Guo DA

更新日期：2010-12-01 00:00:00

abstract：:Crocetin (5-20 microg/ml), quercetin (10-40 microg/ml), and cisplatin (60-180 microg/ml) used as a positive control drug, were tested against human rhabdomyosarcoma (RD) cells and African green monkey kidney (Vero) cells. The cell viability, morphological changes, and lactate dehydrogenase activity were assessed. RD c...

journal_title：Fitoterapia

authors： Jagadeeswaran R,Thirunavukkarasu C,Gunasekaran P,Ramamurty N,Sakthisekaran D

更新日期：2000-08-01 00:00:00

abstract：:Cyperenoic acid (1) is one of the major sesquiterpenes isolated from Croton crassifolius, which exhibited potent anti-angiogenic activity. Traditional structural modification of 1 is difficult to perform by chemical technology due to the remarkable stability of the patchoulane skeleton. In order to overcome chemical s...

journal_title：Fitoterapia

authors： Chen Y,Tian JL,Wu JS,Sun TM,Zhou LN,Song SJ,You S

更新日期：2017-04-01 00:00:00

abstract：:Extracts of the leaves of Securinega leucopyrus exhibited a broad spectrum of antimicrobial activity. ...

journal_title：Fitoterapia

authors： Bakshu LM,Jeevan Ram A,Venkata Raju R

更新日期：2001-12-01 00:00:00

abstract：:Anti-nociceptive and anti-oedematogenic effects of the aqueous extract from the leaves of Erythrina velutina were tested through experimental models of nociception in mice and paw oedema induced by carrageenin in rats. The extract (300 and 600 mg/kg) did not change the carrageenin-induced paw oedema. In the hot plate ...

journal_title：Fitoterapia

authors： Marchioro M,Blank Mde F,Mourão RH,Antoniolli AR

更新日期：2005-12-01 00:00:00

abstract：:Rheum palmatum Linn has been widely applied in the clinical treatment of diabetes mellitus. It has been found that emodin as the major bioactive component of R. palmatum L exhibits the competency to activate peroxisomal proliferator-activated receptor-gamma (PPARgamma) in vitro. So the aim of this study was to evaluat...

journal_title：Fitoterapia

authors： Xue J,Ding W,Liu Y

更新日期：2010-04-01 00:00:00

abstract：AIM:The current study was designed to explore the mechanism of the prokinetic activity of Gentiopicroside (Ge), from Gentiana macrophylla Pall which is widely used to strengthen gastric motility in clinic. METHODS:Gastrointestinal motility disorder rats were induced by stress stimulation and the rats were treated with...

journal_title：Fitoterapia

authors： Ruan M,Yu B,Xu L,Zhang L,Long J,Shen X

更新日期：2015-06-01 00:00:00

abstract：:Activity-guided fractionation of the methanol extract of Vitis vinifera bark led to the isolation of epsilon-viniferin, ampelopcin A, vitisin A and vitisin B. Vitisin A and vitisin B showed a remarkable inhibitory activity against 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase with IC50 value of 42.1 microM...

journal_title：Fitoterapia

authors： Koo M,Kim SH,Lee N,Yoo MY,Ryu SY,Kwon DY,Kim YS

更新日期：2008-04-01 00:00:00

abstract：:Three new xanthones, cylindroxanthones A-C (1-3), were isolated from the stem bark of Garcinia cylindrocarpa. The structures were established on the basis of spectroscopic analysis. The molecular structure of 1 was unequivocally confirmed by single-crystal X-ray diffraction analysis. These three xanthones were evaluat...

journal_title：Fitoterapia

authors： Sukandar ER,Ersam T,Fatmawati S,Siripong P,Aree T,Tip-pyang S

更新日期：2016-01-01 00:00:00

abstract：:The essential oil from the aerial parts of Seseli annuum, wild-growing in Serbia, was obtained by hydrodistillation and analyzed using GC and GC/MS. A total of 43 components were identified representing 96.5% of S. annuum oil. The most abundant compounds were germacrene D (29.8%), sabinene (10.3%), beta-ocimene Z (9.8...

journal_title：Fitoterapia

authors： Milosavljević S,Tesević V,Vucković I,Jadranin M,Vajs V,Soković M,Janaćković P,Jovanović A

更新日期：2007-06-01 00:00:00

abstract：:The antioxidant activity of Agrimonia eupatoria (Agrimony) and Agrimonia procera (Fragrant agrimony) extracts was assessed by measuring in DPPH radical scavenging and ABTS(+) radical decolourisation reaction systems. Radical scavenging capacity of agrimony extracts varied in a wide range (9.1-97.5% in DPPH reaction an...

journal_title：Fitoterapia

authors： Venskutonis PR,Skemaite M,Ragazinskiene O

更新日期：2007-02-01 00:00:00

abstract：:Four new compounds, including three new steroids (1-3) and one new sesquiterpene (6), and two new natural products (4-5), as well as three known steroids (7-9) were isolated from the twigs of Turraea pubescens. Compounds 3-5 are C₂₂ steroids isolated from the Meliaceae family for the first time. Their structures were ...

journal_title：Fitoterapia

authors： Yuan CM,Tang GH,Wang XY,Zhang Y,Cao MM,Li XH,Li Y,Li SL,Di YT,He HP,Hao XJ,Hua HM

更新日期：2013-10-01 00:00:00

abstract：:Eighteen alkaloids were detected in the bark, leaves, wood and roots of Peumus boldus, including traces of secoboldine, N-methylsecoboldine (boldine methine), glaucine and norreticuline, not reported previously as constituents of this species. Using appropriate standards, we quantified thirteen of them by UHPLC-MS/MS....

journal_title：Fitoterapia

authors： Fuentes-Barros G,Castro-Saavedra S,Liberona L,Acevedo-Fuentes W,Tirapegui C,Mattar C,Cassels BK

更新日期：2018-06-01 00:00:00

abstract：:Claims that Traditional/Alternative medicine (TM/AM) remedies are effective are routinely ignored by Western Medicine. However, the results of a clinical trial that demonstrated the clinical efficacy of Tripterygium wilfordii Hook F. (TW), a TM used as an anti-inflammatory, were recently published in the Annals of Int...

journal_title：Fitoterapia

authors： Marks WH

更新日期：2011-01-01 00:00:00

abstract：:Sauruchinenols A (1) and B (2), two novel monocyclic diterpenes with unique carbon skeleton, as well as two new structurally related diterpenes, sauruchinenols C (3) and D (4), were isolated from the aerial part of Saururus chinensis. Their structures were elucidated based on the analysis of spectroscopic data. A hypo...

journal_title：Fitoterapia

authors： Gao X,He J,Wu XD,Peng LY,Shao LD,Li Y,Cheng X,Zhao QS

更新日期：2017-01-01 00:00:00

abstract：:Piper laetispicum C.DC. (Piperaceae), is an endemic climbing, glabrous plant distributed in the southern part of China. A novel alkaloid amide, Laetispicine, from it has been proven to possess antidepressant activity. In this present study, antidepressant and antinociceptive effects of the ethyl acetate extract (EAE) ...

journal_title：Fitoterapia

authors： Xie H,Yan MC,Jin D,Liu JJ,Yu M,Dong D,Cai CC,Pan SL

更新日期：2011-10-01 00:00:00

abstract：:Fruit's decoctions of Passiflora edulis and P. foetida var. albiflora were evaluated for the inhibition of activity of gelatinase MMP-2 and MMP-9, two metallo-proteases involved in the tumour invasion, metastasis and angiogenesis. Both water extracts, at different concentrations, inhibited the enzymes. ...

journal_title：Fitoterapia

authors： Puricelli L,Dell'Aica I,Sartor L,Garbisa S,Caniato R

更新日期：2003-04-01 00:00:00

abstract：:An endophytic fungal strain named Trichoderma atroviride was isolated from the bulb of Lycoris radiata. Following cultivation on rice medium, a novel 3-amino-5-hydroxy-5-vinyl-2-cyclopenten-1-one dimer, atrichodermone A (1), a new cyclopentenone derivative, atrichodermone B (2), and a new sesquiterpene, atrichodermone...

journal_title：Fitoterapia

authors： Zhou P,Wu Z,Tan D,Yang J,Zhou Q,Zeng F,Zhang M,Bie Q,Chen C,Xue Y,Luo Z,Wang J,Zhu H,Zhang Y

更新日期：2017-11-01 00:00:00

abstract：:The alkaloidal fraction obtained from an ethanolic extract of the leaves of Mikania cordata exhibited significant in vivo antiulcer activity in diclofenac sodium-induced gastric erosions in Long Evans rats. ...

journal_title：Fitoterapia

authors： Paul RK,Jabbar A,Rashid MA

更新日期：2000-12-01 00:00:00

abstract：:Two new natural products, 5-O-[β-D-apiofuranosyl-(1→6)-β-d-glucopyranosyl]-1-isoindolinone (1) as well as N-(2E)-3-[(2S,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]acryloylglycine (2), along with four known compounds (3-6), were isolated from the methanolic extract of Co...

journal_title：Fitoterapia

authors： Fouseki MM,Damianakos H,Karikas GA,Roussakis C,P Gupta M,Chinou I

更新日期：2016-12-01 00:00:00