Abstract：
:One new phenanthrene, aphyllone A (1) and four new bibenzyl derivatives, aphyllone B (2) and aphyllals C-D (3-5), together with nine known compounds (6-14), were isolated from the stems of Dendrobium aphyllum (Roxb.) C. E. Fischer. The structures of these new compounds were elucidated by means of extensive spectroscopic analyses, and the absolute configuration of compound 1 was determined by single crystal X-ray diffraction and quantum calculations. Compounds 6, 8 and 14 inhibited NO production at the concentration of 25 μM in LPS-stimulated RAW264.7 cells with the inhibition (%) of 32.48, 35.68, and 38.50. Compound 2 possessed significant DPPH radical scavenging activity with scavenging percentage of 87.97% at the concentration of 100 μg/mL.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Yang D,Liu LY,Cheng ZQ,Xu FQ,Fan WW,Zi CT,Dong FW,Zhou J,Ding ZT,Hu JMdoi
10.1016/j.fitote.2014.11.004subject
Has Abstractpub_date
2015-01-01 00:00:00pages
11-8eissn
0367-326Xissn
1873-6971pii
S0367-326X(14)00291-3journal_volume
100pub_type
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