Abstract：
:Different lines of experimental evidence indicate that treatment with extracts from and derivatives of Phaseolus vulgaris reduces intake of food, including highly palatable foods and beverages, in rats. The present study was designed to extend to mice these lines of evidence. To this end, CD1 mice were treated acutely with a standardized extract of P. vulgaris and then exposed to unlimited access to regular food pellets (Experiment 1) or 1-hour limited access to three different palatable foods/beverages, such as butter cookies (Experiment 2), a condensed-milk beverage (Experiment 3), and a chocolate-flavored beverage (Experiment 4). Treatment with P. vulgaris extract resulted in a significant reduction in the intake of regular food pellets, that was still evident 24h later, as well as of the three palatable nourishments. Together, these results (a) extend to mice several previous findings on the capacity of P. vulgaris extracts to suppress food intake in rats, (b) suggest that P. vulgaris extracts may interfere with the central mechanisms regulating appetite, food intake, palatability, and/or the rewarding and hedonic properties of food, and (c) P. vulgaris extracts may represent a potentially effective therapy for overeating, obesity, and food craving.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Loi B,Fantini N,Colombo G,Gessa GL,Riva A,Bombardelli E,Morazzoni P,Carai MAdoi
10.1016/j.fitote.2012.12.015subject
Has Abstractpub_date
2013-03-01 00:00:00pages
14-9eissn
0367-326Xissn
1873-6971pii
S0367-326X(12)00342-5journal_volume
85pub_type
杂志文章相关文献
FITOTERAPIA文献大全abstract：:A new diterpenoid ester, fritillahupehin (1) together with three known fatty acids: palmitic acid (2), lignoceric acid (3) and azelaic acid (4) were isolated from the bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia. The structure of fritillahupehin has been established to be ent-kauran-16beta-yl lignocerate by mea...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(02)00085-0
更新日期：2002-07-01 00:00:00
abstract：:The inhibitory activity of alpha-amylase and the phytochemical composition of Cedrus libani essential oils obtained from wood, leaves and cones were investigated. The C. libani woods oil exhibit an IC(50) value of 0.14 mg/ml, whereas the leaves and cones oils were devoid of any significant activity. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2007.03.006
更新日期：2007-06-01 00:00:00
abstract：:Tithonia diversifolia (Asteraceae), is used as traditional medicine in tropical countries for the treatment of various diseases, including malaria. Although numerous studies have assessed the antimalarial properties, nothing is known about the effect of T. diversifolia extracts on trypanosomiasis. In this study extrac...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2017.11.002
更新日期：2018-01-01 00:00:00
abstract：:Usually isolated from Garcinia (Clusiaceae) or Hypericum (Hypericaceae) species, some Polycyclic Polyprenylated AcylPhloroglucinols (PPAPs) have been recently reported as potential research tools for immunotherapy. Aiming at exploring the chemodiversity of PPAPs amongst Garcinia genus, a dereplication process suitable...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2018.10.003
更新日期：2018-11-01 00:00:00
abstract：:Oplopanax horridus or devil's club is a herbal medicine distributed in North America. The constituents and pharmacological activities of O. horridus (OPH) are largely unknown. In this study, we assayed OPH stem and berry extracts using high performance liquid chromatography (HPLC). The anticancer potentials of extract...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2009.08.003
更新日期：2010-03-01 00:00:00
abstract：:Oral treatment with the water extracts of Scoparia dulcis whole aerial parts, at doses of 50, 100 and 200 mg/kg, dose dependently inhibited the indomethacin-induced gastric damages in rats. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2008.05.001
更新日期：2008-12-01 00:00:00
abstract：:Wedelia (Sphagneticola trilobata, Syn. Wedelia trilobata), a notoriously invasive agricultural weed, can inhibit the growth and development of crops in the field. Eight new eudesmanolides (1-8), along with twelve known congeners (9-20), were isolated and identified from the flowers of Wedelia. Their chemical structure...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2019.104452
更新日期：2020-04-01 00:00:00
abstract：:Five pairs of new 2-oxoindole alkaloids, (±)-peganumalines A-E (1-5), and a new indole alkaloid, peganumaline F (6), along with two known analogues, were isolated from the seeds of Peganum harmala. Their structures and absolute configurations were elucidated through spectroscopic analyses and quantum chemistry calcula...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2018.01.008
更新日期：2018-03-01 00:00:00
abstract：:Influenza poses a particular risk of severe outcomes in the elderly, the very young and those with underlying diseases. Tea polyphenols are the natural phenolic compounds in teas, and principally consist of catechins, proanthocyanidins, flavonols, and theaflavins, which antiviral activities have been reported recently...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.12.011
更新日期：2014-03-01 00:00:00
abstract：:Two new depsidones, schomburgdepsidones A and B (1 and 2), and one new xanthone, schomburgxanthone A (3), together with eight known compounds (4-11) were isolated from the roots of Garcinia schomburgkiana. Their chemical structures were established on the basis of spectroscopic analysis. The in vitro cytotoxicity of a...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2016.04.012
更新日期：2016-06-01 00:00:00
abstract：:Cyclotides describe a unique cyclic peptide family that displays a broad range of biological activities including uterotonic, anti-bacteria, anti-cancer and anti-HIV. The vigno cyclotides consist of vigno 1-10 were reported recently from Viola ignobilis. In the present study, we examined the effects of vigno 5, a natu...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.12.021
更新日期：2016-03-01 00:00:00
abstract：:The aqueous extract of the Cocculus hirsutus aerial parts (100 and 200 mg/kg, p.o.) showed significant diuretic activity and laxative effect in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(01)00345-8
更新日期：2002-02-01 00:00:00
abstract：:A new C(18)-phytosphingosine ceramide containing non-hydroxy fatty acid, armillaramide (1), has been isolated together with ergosterol peroxide from the fruiting bodies of the basidiomycete Armillaria mellea. Its structure was established as (2S,3S,4R)-2-hexadecanoylamino-octadecane-1,3,4-triol by spectroscopic and ch...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/s0367-326x(01)00319-7
更新日期：2001-12-01 00:00:00
abstract：:As a part of our ongoing search for plant-derived compounds that inhibit nitric oxide production, the methanol extract of the roots of Vladimiria souliei was found to show significant inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells. Bioactivity-guided isolation of the ex...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2011.01.004
更新日期：2011-04-01 00:00:00
abstract：:Beyond its role in the activation of protein C, the endothelial cell protein C receptor (EPCR) plays an important role in the cytoprotective pathway. EPCR can be shed from the cell surface, which is mediated by tumor necrosis factor-α converting enzyme (TACE). Polyozellin, a major constituent of a Korea edible mushroo...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.11.005
更新日期：2016-01-01 00:00:00
abstract：:A new degraded limonoid, named isodictamdiol A (1), two known degraded limonoids (2, 3) and a new nature product of quinoline alkaloid (4) along with five known quinoline alkaloids (5-9) were isolated from the root bark of Dictamnus angustifolius G. Don ex Sweet.. Certain useful NMR data were generalized to determine ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2013.07.023
更新日期：2013-10-01 00:00:00
abstract：:Acteoside, which belongs to the family of phenylethanoid glycosides (PhGs), has extensive biological activities, including strong antioxidant, anti-inflammatory, hepatoprotect, and cell apoptosis regulation. Like other PhGs compounds, the fate of acteoside in the gut for both parent polyphenols and their degradation p...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2016.05.004
更新日期：2016-07-01 00:00:00
abstract：:Cranberry procyanidins and quercetin derivatives are considered possible active compounds against urinary tract infections (UTIs). In this paper a small group (n=6) of healthy subjects consumed a product containing 360mg of cranberry extract (42.6% w/w of PAC-A and 14.6% w/w of PAC-B) and 200mg of quercetin. Urine sam...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2017.08.014
更新日期：2017-10-01 00:00:00
abstract：:The antioxidant activity of Citrus paradisi (grapefruit) seeds glyceric extract dissolved in ethanol and in aqueous media was evaluated using three different methods: evaluation by DPPH assay, by 5-lipoxygenase assay and by luminol/xanthine/xanthine oxidase chemiluminescence assay. The total phenolic content was deter...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2003.12.010
更新日期：2004-03-01 00:00:00
abstract：:There is growing evidence that motherwort (Leonurus japonicus Houtt.), and Chinese patent medicines derived from motherwort, alleviate postpartum uterine subinvolution, as well as the effects on myocardial and cerebral ischemic injuries. We hypothesized that these beneficial effects of motherwort may be related to ang...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2018.05.002
更新日期：2018-07-01 00:00:00
abstract：:Thuja occidentalis L. is indigenous for Northern America and commonly cultivated in Europe. Raw materials obtained from this tree are widely applied in the ethnomedicine and phytotherapy of numerous ailments, incl. scurvy, cystitis, rheumatism and cancer. Despite wide medicinal applications of Thuja occidentalis, stil...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2019.02.020
更新日期：2019-04-01 00:00:00
abstract：:A chemical investigation of the 80% EtOH extract of the aerial plant of Alstonia rupestris afforded four new monoterpenoid indole alkaloids, 6,7-epoxy-8-oxo-vincadifformine (1), 11-acetyl-6,7-epoxy-8-oxo-vincadifformine (2), 11-hydroxy-14-chloro-15-hydroxy-vincadifformine (3), and perakine N1,N4-dioxide (4), together ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2014.05.018
更新日期：2014-09-01 00:00:00
abstract：:Cinnamon is the dried bark of Cinnamomum cassia Presl, and its main component is cinnamaldehyde (CA). Decades of synthetic pesticide use to control parasitic nematodes that can harm plants has seriously polluted the environment and poses a risk to soil ecology, highlighting the need to develop natural biological pesti...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2020.104687
更新日期：2020-10-01 00:00:00
abstract：:Picrasamide A (1), a new cinnamamide derivative, together with two new β-carboline alkaloids (2 and 3) and five known β-carboline alkaloids (4-8) were isolated from the stems of Picrasma quassioides (D. Don) Benn. Their structures were elucidated by detailed analyses of UV, IR, HRESIMS, and NMR data. Compound 1 was th...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2019.104375
更新日期：2019-11-01 00:00:00
abstract：:Isonuatigenin-3-O-beta-solatriose (1) was isolated from the roots of Solanum sisymbriifolium. Its structure was determined by spectroscopic methods. ...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2005.04.008
更新日期：2005-09-01 00:00:00
abstract：:Six new triterpenoids, pseudolarins A-F (1-6), were isolated from the twigs of Pseudolarix amabilis, together with four known triterpenoids (7-10) and five known diterpenoids (11-15). Their structures were determined by extensive spectroscopic analysis, and the absolute configuration of 1 was assigned by single-crysta...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2019.104414
更新日期：2019-11-01 00:00:00
abstract：:Alkaloids comprise one of the largest groups of plant secondary metabolites including vinca alkaloids. The ability of six alkaloids from Veratrum lobelianum, one from Veratrum nigrum and three from Peganum nigellastrum to modify transport activity of MDR1 was studied. Flow-cytometry in a multidrug-resistant human MDR1...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2011.01.015
更新日期：2011-06-01 00:00:00
abstract：AIM:The current study was designed to explore the mechanism of the prokinetic activity of Gentiopicroside (Ge), from Gentiana macrophylla Pall which is widely used to strengthen gastric motility in clinic. METHODS:Gastrointestinal motility disorder rats were induced by stress stimulation and the rats were treated with...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.04.015
更新日期：2015-06-01 00:00:00
abstract：:In the last 20 years, wine phenolic compounds have received increasing interest since several epidemiological studies have suggested associations between regular consumption of moderate amount of wine and prevention of certain chronic pathologies, such as neurodegenerative diseases. This study was aimed to investigate...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2015.04.003
更新日期：2015-06-01 00:00:00
abstract：:Two new pentacyclic triterpenes named kirmanoic acid (1) and kurramanoic acid (2) have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei Hook. The structures of the two new compounds were assigned on the basis of their ¹H and ¹³C NMR spectra including two-dimensional NMR techniques...
journal_title：Fitoterapia
pub_type： 杂志文章
doi：10.1016/j.fitote.2012.01.002
更新日期：2012-04-01 00:00:00
