Degraded limonoids and quinoline alkaloids from Dictamnus angustifolius G. Don ex Sweet. and their anti-platelet aggregation activity.

abstract：:Although the nature-identical chemical compounds are cheaper, they not always repeat biological activity of plant origin natural chemical compounds, often react allergies and resistance of microorganisms. The aim of this study was to investigate effects of Juniperus communis origin α-pinene with different enantiomeric...

journal_title：Fitoterapia

authors： Ložienė K,Švedienė J,Paškevičius A,Raudonienė V,Sytar O,Kosyan A

更新日期：2018-06-01 00:00:00

abstract：:A new C(18)-phytosphingosine ceramide containing non-hydroxy fatty acid, armillaramide (1), has been isolated together with ergosterol peroxide from the fruiting bodies of the basidiomycete Armillaria mellea. Its structure was established as (2S,3S,4R)-2-hexadecanoylamino-octadecane-1,3,4-triol by spectroscopic and ch...

journal_title：Fitoterapia

authors： Gao JM,Yang X,Wang CY,Liu JK

更新日期：2001-12-01 00:00:00

abstract：:The inhibitory activity of alpha-amylase and the phytochemical composition of Cedrus libani essential oils obtained from wood, leaves and cones were investigated. The C. libani woods oil exhibit an IC(50) value of 0.14 mg/ml, whereas the leaves and cones oils were devoid of any significant activity. ...

journal_title：Fitoterapia

authors： Loizzo MR,Saab AM,Statti GA,Menichini F

更新日期：2007-06-01 00:00:00

abstract：:The effect of schisandrin B (Sch B) on long-term ethanol-induced oxidative stress in various rat tissues was investigated. Long-term ethanol treatment increased reactive oxygen metabolites (ROM) level in plasma. The ethanol-induced oxidative stress was assessed by mitochondrial glutathione and α-tocopherol levels, ant...

journal_title：Fitoterapia

authors： Lam PY,Chiu PY,Leung HY,Chen N,Leong PK,Ko KM

更新日期：2010-12-01 00:00:00

abstract：:The effects of aqueous extracts of Celastrus paniculatus (CP) seeds were shown to have antioxidant properties in rats. In the study reported here, we have investigated the free radical scavenging capacity of three aqueous extracts (WSEs) obtained from CP seeds: a room temperature extract (WF); a hot water extract (HF)...

journal_title：Fitoterapia

authors： Godkar P,Gordon RK,Ravindran A,Doctor BP

更新日期：2003-12-01 00:00:00

abstract：:The ecological role of maytansine, an important antineoplastic and antimicrobial compound with high cytotoxicity, particularly as a chemical defense compound has remained elusive since its discovery in the 1970s in Maytenus and Putterlickia plants. In the present study, we have used MALDI-imaging-HRMS to visualize the...

journal_title：Fitoterapia

authors： Eckelmann D,Kusari S,Spiteller M

更新日期：2017-06-01 00:00:00

abstract：:The high edible oil content of Xanthoceras sorbifolia Bunge seeds contributes to its economic value. In this study, we analysed the barrigenol-like triterpenoids derived from X. sorbifolia husks. We also identified anti-tumour agents that could enhance the health benefits and medicinal value of X. sorbifolia. We isola...

journal_title：Fitoterapia

authors： Wang D,Su D,Yu B,Chen C,Cheng L,Li X,Xi R,Gao H,Wang X

更新日期：2017-01-01 00:00:00

abstract：:The tea seed triterpene saponin (TS) from Camellia sinensis was found to exhibit better antitumor activity in vivo in S180 implanted ICR mice and QR inducing activity for hepa lclc7 cells respectively compared with the total tea seed saponin (TTS), hydrolysate of the TTS and tea seed flavonoid glycosides (TF). By bioa...

journal_title：Fitoterapia

authors： Li N,Ma ZJ,Chu Y,Wang Y,Li X

更新日期：2013-01-01 00:00:00

abstract：:Total sennosides concentration is a very important factor when rhubarb and senna will be used as crude drugs. However, one-step analytical technique for total sennosides has not been reported except HPLC. An enzyme-linked immunosorbent assay (ELISA) for total sennosides concentration by using the combination of anti-s...

journal_title：Fitoterapia

authors： Morinaga O,Uto T,Sakamoto S,Tanaka H,Shoyama Y

更新日期：2009-01-01 00:00:00

abstract：:Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous ...

journal_title：Fitoterapia

authors： Lee HJ,Cho JY,Moon JH

更新日期：2012-10-01 00:00:00

abstract：:Three new glucosides, namely, (-)-7R8S-7',8'-dihydroxy-dihydrodehydroconiferyl alcohol-9-O-β-D-glucopyranoside (1), (+)-7S8R-7',8'-dihydroxy-dihydrodehydroconiferyl alcohol-9-O-β-D-glucopyranoside (2) and 4-hydroxy-2-methoxyphenyl 1-O-[6-(hydrogen 3-hydroxy-3-methylpentanedioate)]-β-D-glucopyranoside (3), along with 6...

journal_title：Fitoterapia

authors： Hu J,Zhao J,Khan SI,Liu Q,Liu Y,Ali Z,Li XC,Zhang SH,Cai X,Huang HY,Wang W,Khan IA

更新日期：2014-12-01 00:00:00

abstract：:Three new xanthones, named kaennacowanols A-C (1-3), along with nineteen known xanthones were isolated from the roots of Garcinia cowa Roxb. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against KB and HeLa cell lines. Compounds 17 and 22 showe...

journal_title：Fitoterapia

authors： Kaennakam S,Siripong P,Tip-Pyang S

更新日期：2015-04-01 00:00:00

abstract：:Beyond its role in the activation of protein C, the endothelial cell protein C receptor (EPCR) plays an important role in the cytoprotective pathway. EPCR can be shed from the cell surface, which is mediated by tumor necrosis factor-α converting enzyme (TACE). Polyozellin, a major constituent of a Korea edible mushroo...

journal_title：Fitoterapia

authors： Lee W,Yang EJ,Park DH,Bae JS

更新日期：2016-01-01 00:00:00

abstract：:Cordia dichotoma f. (Boraginaceae) is a small deciduous tree from India. The bark of was used in the treatment of ulcerative colitis (UC) and colic pain traditionally hence present work was undertaken to identify the phytoconstituent responsible for this activity. Apigenin is isolated by column chromatography from met...

journal_title：Fitoterapia

authors： Ganjare AB,Nirmal SA,Patil AN

更新日期：2011-10-01 00:00:00

abstract：:Two new ent-kaurene diterpenoids, 15α-acetoxyl-6,11α-epoxy-6α-hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7-olide (1), 15α-hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide (2), together with ten known compounds (5-14) were isolated from the leaves of Isodon rubescens. Their structures were elucidated mainly by ...

journal_title：Fitoterapia

authors： Xie RJ,Yan FL,Hai GF,Hou RJ,Ding MM,Bai YX

更新日期：2011-06-01 00:00:00

abstract：:Six new triterpenoids, pseudolarins A-F (1-6), were isolated from the twigs of Pseudolarix amabilis, together with four known triterpenoids (7-10) and five known diterpenoids (11-15). Their structures were determined by extensive spectroscopic analysis, and the absolute configuration of 1 was assigned by single-crysta...

journal_title：Fitoterapia

authors： Lei C,Huang QH,Zhao T,Wang PP,Li JY,Li J,Hou AJ

更新日期：2019-11-01 00:00:00

abstract：:A new steroidal alkaloid, (-)-veranigrine (1) was isolated from the roots and rhizomes of Veratrum nigrum L. By means of spectroscopic methods its structure was established as (20S, 25S)-iminocholesta-5,22(N)-diene-1beta,3beta-diol. ...

journal_title：Fitoterapia

authors： Christov V,Mikhova B,Selenge D

更新日期：2009-01-01 00:00:00

abstract：:Australian native plants have a long history of therapeutic use in indigenous cultures, however, they have been poorly studied scientifically. We analysed the effects of 14 plant derived compounds from the species Pilidiostigma glabrum, Myoporum montanum, Geijera parviflora, and Rhodomyrtus psidioides for their potent...

journal_title：Fitoterapia

authors： Adams DH,Shou Q,Wohlmuth H,Cowin AJ

更新日期：2016-03-01 00:00:00

abstract：:Two new minor cyclopeptides, named japonicin A (1), japonicin B (2), were isolated from the whole plants of Sagina japonica (Caryophyllaceae). Their structures were determined as cyclo-(Pro(1)-Pro(2)-Leu(2)-Leu(1)-Phe(2)-Pro(3)-Gly-Ser-Phe(1)) (1) and cyclo-(Pro(1)-Ile-Tyr-Asp-Pro(2)-Phe(2)-Pro(3)-Phe(1)) (2) on the b...

journal_title：Fitoterapia

authors： Jia AQ,Tan NH,Zhou J

更新日期：2009-04-01 00:00:00

abstract：:Solanum nigrum L. (also called as European black nightshade) has been traditionally used as folk medicine and food in some regions. Phytochemical investigations of the immature fruits of S. nigrum yielded five steroidal alkaloid glycosides (1-5), including an unprecedented nor-spirosolane type steroidal alkaloid with ...

journal_title：Fitoterapia

authors： Xiang L,Wang Y,Yi X,He X

更新日期：2019-09-01 00:00:00

abstract：:The secondary metabolite pattern of Eryngium tricuspidatum has been found to be dominated by C17 acetylene oxylipins, according to the chemistry reported in the literature for the genus Eryngium. Two new oxylipins, 11-acetoxy-falcarindiol (4) and 1,2-dihydro-11-acetoxy-falcarindiol (5) have been isolated, along with m...

journal_title：Fitoterapia

authors： Djebara A,Ciavatta ML,Mathieu V,Colin M,Bitam F,Carbone M,Gavagnin M

更新日期：2019-10-01 00:00:00

abstract：:The estrogenicity of different batches of red clover (Trifolium pratense L., Fabaceae; RCL) extracts and its relationship with the isoflavone content were assessed by measuring MCF-7 cell proliferation by flow cytometry and propidium iodide staining. RCL extracts were compared to estradiol (E2) and to the main RCL iso...

journal_title：Fitoterapia

authors： Spagnuolo P,Rasini E,Luini A,Legnaro M,Luzzani M,Casareto E,Carreri M,Paracchini S,Marino F,Cosentino M

更新日期：2014-04-01 00:00:00

abstract：:Three new caged polyprenylated benzophenone derivatives named burlemarxiones D-F (1-3) were isolated from the hexane extract of Clusia burle-marxii trunks. Burlemarxione D (1) contains the tetracyclo[8.3.1.03,11.05,10]tetradecane core skeleton also observed for burlemarxione A, its probable immediate precursor. Howeve...

journal_title：Fitoterapia

authors： Ferraz CG,Ribeiro PR,Mendonça R,Silveira ER,Cruz FG

更新日期：2020-10-16 00:00:00

abstract：:Diketopiperazine is a natural products found from bacteria, fungi, marine sponges, gorgonian and red algae. They are cyclic dipeptides possessing relatively simple and rigid structures with chiral nature and various side chains. The compounds in this structure class have been known to possess diverse bioactivities inc...

journal_title：Fitoterapia

authors： Lee W,Ku SK,Choi H,Bae JS

更新日期：2016-04-01 00:00:00

abstract：:The effect of asiaticoside isolated from Hydrocotyle sibthorpioides (AHS) on the promotion of cognition in senescence-accelerated mice (SAMP) was evaluated. Six-month old male SAMP8 mice were orally administered 20, 40 or 80 mg/kg AHS daily for three months. SAMR1 mice were used as a "normal aging" control. The result...

journal_title：Fitoterapia

authors： Lin X,Huang R,Zhang S,Wei L,Zhuo L,Wu X,Tang A,Huang Q

更新日期：2013-06-01 00:00:00

abstract：:Calcium-activated chloride channels (CaCCs) as a kind of widely expressed ion channels play crucial roles in a variety of physiological regulation. TMEM16A has been identified as the molecular basis of CaCCs in numerous cell types and is considered a new drug target for many diseases. Regulating the function of TMEM16...

journal_title：Fitoterapia

authors： Zhu X,Zhang W,Jin L,Zhang G,Yang H,Yu B

更新日期：2020-11-01 00:00:00

abstract：:Reinvestigation of Onopordon ambiguum extract afforded a new eudesmane derivative 1, in addition to the known elemanoid derivative 2. The structures of both compounds were determined by spectroscopic techniques, including 1H-, 13C-NMR, DEPT, 1H-1H and 1H-13C COSY analysis. ...

journal_title：Fitoterapia

authors： El-Moghazy SA,Ahmed AA,Abdel-Ghani HF,El-Shanawany MA

更新日期：2002-02-01 00:00:00

abstract：:The effect of basil oil on the phagocytic capability and respiratory burst response of mouse peritoneal macrophages was studied. The oil inhibited the phagocytosis of opsonized sheep erythrocytes. This inhibition was both dose- and time-dependent and reverted 24 h after removing the extract from the culture medium. On...

journal_title：Fitoterapia

authors： Courrèges MC,Benencia F

更新日期：2002-08-01 00:00:00

abstract：:The estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum and five fractions obtained by solid-phase extraction were investigated using estrogen-responsive bioassays, a yeast cell assay and the Ishikawa Var-I assay. The extract was found to exhibit significant estrogenic activity in both...

journal_title：Fitoterapia

authors： De Naeyer A,Pocock V,Milligan S,De Keukeleire D

更新日期：2005-01-01 00:00:00

abstract：:Cajaninstilbene acid (CSA), a bioactive constituent isolated from pigeon pea leaves, exhibited neuroprotective activities in previous studies. The present study aims to evaluate the antidepressant effects of CSA by using behavioral despair models of tail suspension test (TST) and forced swimming test (FST), and a chro...

journal_title：Fitoterapia

authors： Zhang MD,Tao X,Pan RL,Wang LS,Li CC,Zhou YF,Liao YH,Chen SG,Chang Q,Liu XM

更新日期：2020-03-01 00:00:00