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Tricycloalternarenes F-H: three new mixed terpenoids produced by an endolichenic fungus Ulocladium sp. using OSMAC method.

Abstract：

:Three new mixed terpenoids, tricycloalternarenes (TCAs) F-H (1-3), together with ten known tricycloalternarenes (4-13), were isolated from the Czapek's culture of an endophytic fungus Ulocladium sp. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data. TCA 1b (5) showed weak activity against the Bacille Calmette-Guerin strain with the MIC of 125μg/mL. TCA 9b (10) exhibited strong cytotoxic activity against Hela cell line with IC50 of 8.58μM.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Wang QX,Bao L,Yang XL,Guo H,Ren B,Guo LD,Song FH,Wang WZ,Liu HW,Zhang LX

doi

10.1016/j.fitote.2012.12.029

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

8-13

eissn

0367-326X

issn

1873-6971

pii

S0367-326X(12)00356-5

journal_volume

85

pub_type

杂志文章

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