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Antimicrobial and cytotoxicity evaluation of Buchholzia coriacea stem bark.

Abstract：

:Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with an LC(50) of 1031 microg/ml. The two main compounds present in the most active fraction were isolated and identified as lupeol and beta-sitosterol.

journal_name

Fitoterapia

journal_title

Fitoterapia

authors

Ajaiyeoba EO,Onocha PA,Nwozo SO,Sama W

doi

10.1016/s0367-326x(03)00142-4

keywords:

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

706-9

issue

7-8

eissn

0367-326X

issn

1873-6971

pii

S0367326X03001424

journal_volume

74

pub_type

杂志文章

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