Astershionones A-F, six new anti-HBV shionane-type triterpenes from Aster tataricus.

abstract：:The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml a...

journal_title：Fitoterapia

authors： Psotová J,Chlopcíková S,Miketová P,Simánek V

更新日期：2005-09-01 00:00:00

abstract：:A new arylnaphthalene lignan, named furfuracin, was isolated from the leaves of Knema furfuracea (Myristicaceae), whereas 7 known compounds including (+)-trans-1,2-dihydrodehydroguaiaretic acid, fragransin A(2), biochanin A, gingkolic acid, anarcardic acid, 2-hydroxy-6-(12-phenyldodecyl)-benzoic acid and 2-hydroxy-6-(...

journal_title：Fitoterapia

authors： Rangkaew N,Suttisri R,Moriyasu M,Kawanishi K

更新日期：2009-09-01 00:00:00

abstract：:Although the nature-identical chemical compounds are cheaper, they not always repeat biological activity of plant origin natural chemical compounds, often react allergies and resistance of microorganisms. The aim of this study was to investigate effects of Juniperus communis origin α-pinene with different enantiomeric...

journal_title：Fitoterapia

authors： Ložienė K,Švedienė J,Paškevičius A,Raudonienė V,Sytar O,Kosyan A

更新日期：2018-06-01 00:00:00

abstract：:Before the design of brucine-containing transdermal formulations, the pharmacodynamics and pharmacokinetics of brucine following transdermal administration should be evaluated. In this study, the effect of addition of ethanol on solubility of bruicne was investigated and 20% ethanol was added into PBS to obtain 10mg/m...

journal_title：Fitoterapia

authors： Chen J,Hu W,Qu YQ,Dong J,Gu W,Gao Y,Fang Y,Fang F,Chen ZP,Cai BC

更新日期：2013-04-01 00:00:00

abstract：:Five new cadinene-type sesquiterpenes, hibiscusterpenes I-V (1-5), and six known compounds (6-11) have been isolated from the methanol extract of the stems and the twigs of Hibiscus tiliaceus. The structures of the new compounds were elucidated based on chemical and spectroscopic evidence. The absolute stereochemistry...

journal_title：Fitoterapia

authors： Μatsumoto T,Imahori D,Achiwa K,Saito Y,Ohta T,Yoshida T,Kojima N,Yamashita M,Nakayama Y,Watanabe T

更新日期：2020-04-01 00:00:00

abstract：:The alkaloidal fraction obtained from an ethanolic extract of the leaves of Mikania cordata exhibited significant in vivo antiulcer activity in diclofenac sodium-induced gastric erosions in Long Evans rats. ...

journal_title：Fitoterapia

authors： Paul RK,Jabbar A,Rashid MA

更新日期：2000-12-01 00:00:00

abstract：:Thirty four terpenoids, including two new cadinane-type sesquiterpenoids containing conjugated aromatic-ketone moieties, curcujinone A (1) and curcujinone B (2), were isolated from 95% ethanol extract of the root tubers of Curcuma wenyujin. Their structures were determined by spectroscopic methods, especially 2D NMR a...

journal_title：Fitoterapia

authors： Zhou CX,Zhang LS,Chen FF,Wu HS,Mo JX,Gan LS

更新日期：2017-09-01 00:00:00

abstract：:Five new koumine-type alkaloids (1-5) along with six known ones were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated on the basis of NMR spectroscopy and electronic circular dichroism spectral analyses. The inhibitory effects of compounds 1-11 on the viabilit...

journal_title：Fitoterapia

authors： Zhang W,Zhang SY,Wang GY,Li NP,Chen MF,Gu JH,Zhang DM,Wang L,Ye WC

更新日期：2017-04-01 00:00:00

abstract：:The effect of berberine hydrochloride (BBR) on inducible cyclooxygenase-2 (COX-2) in small intestinal mucosa and related mechanisms was investigated in a rat model of acute endotoxemia. The results showed that lipopolysaccharide (LPS) increased COX-2 expression, whereas SB202190 and BBR curtailed it. LPS increased pho...

journal_title：Fitoterapia

authors： Feng AW,Yu C,Mao Q,Li N,Li QR,Li JS

更新日期：2011-10-01 00:00:00

abstract：:Four new lignanamides, melongenamides A-D (1-4), together with six known ones (5-10), were isolated from the roots of Solanum melongena L. Their structures were elucidated on the basis of 1D and 2D NMR experiments and by comparison of their spectroscopic and physical data with the literature values. Compounds 2-8 exhi...

journal_title：Fitoterapia

authors： Sun J,Gu YF,Su XQ,Li MM,Huo HX,Zhang J,Zeng KW,Zhang Q,Zhao YF,Li J,Tu PF

更新日期：2014-10-01 00:00:00

abstract：:Silymarin, a standardised extract of Silybum marianum (milk thistle), comprises mainly of silybin, with dehydrosilybin (DHSB), quercetin, taxifolin, silychristin and a number of other compounds which are known to possess a range of salutary effects. Indeed, there is evidence for their role in reducing tumour growth, p...

journal_title：Fitoterapia

authors： Zholobenko A,Modriansky M

更新日期：2014-09-01 00:00:00

abstract：:A new triterpene, 3beta-19alpha-dihydroxy-30-norurs-12-ene (1), has been isolated from the methanolic extract of Debregeasia salicifolia stems. Its structure has been elucidated with the help of one- and two-dimensional NMR and NOE studies. Lupeol, beta-sitosterol, stigmasterol and oleanolic acid are also reported for...

journal_title：Fitoterapia

authors： Akbar E,Riaz M,Malik A

更新日期：2001-05-01 00:00:00

abstract：:Four meroterpenoids, applanatumols F (1), H (3), I (2), and lingzhiol (4) were isolated from the 95% EtOH extract of the fruiting bodies of Ganoderma sinense. Their structures were established on the basis of NMR spectroscopic analyses, optical rotatory dispersion data, ECD spectra, and X-ray crystallography. Compound...

journal_title：Fitoterapia

authors： Gao S,Zhang P,Zhang C,Bao F,Li H,Chen L

更新日期：2018-11-01 00:00:00

abstract：:Diplacone (1) and mimulone (2), two geranylated flavanones, have previously shown anti-inflammatory and antiradical activity in vitro. The present study aimed to evaluate their activity in vivo on a model of colitis induced in Wistar rats by an oral administration of dextran sulfate sodium (DSS). Diplacone (1) and mim...

journal_title：Fitoterapia

authors： Vochyánová Z,Bartošová L,Bujdáková V,Fictum P,Husník R,Suchý P,Šmejkal K,Hošek J

更新日期：2015-03-01 00:00:00

abstract：:Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with a...

journal_title：Fitoterapia

authors： Ajaiyeoba EO,Onocha PA,Nwozo SO,Sama W

更新日期：2003-12-01 00:00:00

abstract：:The methanol extract of the bark of Litsea glutinosa showed antibacterial activity, comparable to chloramphenicol, against all 16 tested microorganisms. ...

journal_title：Fitoterapia

authors： Mandal SC,Kumar CK,Majumder A,Majumder R,Maity BC

更新日期：2000-08-01 00:00:00

abstract：:The pharmacological active genus Thymus L. comprises over 200 species. Besides its traditional pharmacological use, thyme may reduce the risk of caries disease, however, there is very little respective literature. The pharmacological effects can be attributed to the secondary plant metabolites. The composition of the ...

journal_title：Fitoterapia

authors： Schött G,Liesegang S,Gaunitz F,Gleß A,Basche S,Hannig C,Speer K

更新日期：2017-09-01 00:00:00

abstract：:Five vibralactone derivatives containing γ, δ, ε-lactone cores, namely vibralactones X (1), Y (2), and Z1-Z3 (3-5), together with the known vibralactone, have been isolated from cultures of the basidiomycete Boreostereum vibrans. Compounds 3-5 possessed a novel bis-γ-lactone group which was found in vibralactone deriv...

journal_title：Fitoterapia

authors： Duan KT,Li ZH,Yu X,Yuan QX,Wang WX,Li J,Chen HP,Feng T,Liu JK

更新日期：2018-07-01 00:00:00

abstract：:The antifungal activity of fresh, aqueous Brassica oleracea var. botrytis juice against Candida albicans and other pathogenic fungi was investigated. The juice was found to be effective both in inhibiting the growth of blastoconidia and reducing the appearance of C. albicans germ tubes. Furthermore, the juice inhibite...

journal_title：Fitoterapia

authors： Sisti M,Amagliani G,Brandi G

更新日期：2003-07-01 00:00:00

abstract：:Six new flavonoids, seladoeflavones A-F (1-6), were isolated from the whole herbs of Selaginella doederleinii, together with one known flavonoid (7). Their structures including absolute configuration were characterized on the basis of extensive spectroscopic methods including NMR, HRMS, and electronic circular dichroi...

journal_title：Fitoterapia

authors： Zou Z,Xu K,Xu P,Li X,Cheng F,Li J,Yu X,Cao D,Li D,Zeng W,Zhang G,Tan G

更新日期：2017-01-01 00:00:00

abstract：:This paper reports the results of an ethnobotanical survey of medicinal plants used by the Thari people of the Nara Desert, Sindh, Pakistan. Fifty-one plant species distributed across 28 families and 43 genera were discovered to have medicinal uses by local inhabitants of the Nara Desert. Twenty-one of those species a...

journal_title：Fitoterapia

authors： Qureshi R,Raza Bhatti G

更新日期：2008-09-01 00:00:00

abstract：:The ethanolic extract of Lawsonia inermis leaves and lawsone tested for trypsin inhibitory activity showed an IC(50) value of 64.87 and 48.6 microg/ml, respectively. ...

journal_title：Fitoterapia

authors： Yogisha S,Samiulla DS,Prashanth D,Padmaja R,Amit A

更新日期：2002-12-01 00:00:00

abstract：:The ecological role of maytansine, an important antineoplastic and antimicrobial compound with high cytotoxicity, particularly as a chemical defense compound has remained elusive since its discovery in the 1970s in Maytenus and Putterlickia plants. In the present study, we have used MALDI-imaging-HRMS to visualize the...

journal_title：Fitoterapia

authors： Eckelmann D,Kusari S,Spiteller M

更新日期：2017-06-01 00:00:00

abstract：:Activity-guided fractionation of the methanol extract of Vitis vinifera bark led to the isolation of epsilon-viniferin, ampelopcin A, vitisin A and vitisin B. Vitisin A and vitisin B showed a remarkable inhibitory activity against 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase with IC50 value of 42.1 microM...

journal_title：Fitoterapia

authors： Koo M,Kim SH,Lee N,Yoo MY,Ryu SY,Kwon DY,Kim YS

更新日期：2008-04-01 00:00:00

abstract：:Phytochemical investigation of methanolic extract of the whole plants of Vaccinium emarginatum allowed for the characterization of one epicatechin derivative (1) that was isolated from a natural source for the first time and three new flavonoids, emarginin A (2), emarginin B (3), and emarginin C (4), together with 11 ...

journal_title：Fitoterapia

authors： Tu PC,Liang YC,Huang GJ,Huang HC,Kao MC,Lu TL,Kuo YH

更新日期：2020-03-01 00:00:00

abstract：:The plant derived camptothecin (CPT) is a pentacyclic pyrroloquinoline alkaloid with unique antitumor activity. Successive discoveries of new CPT-producing plants occurred in recent years due to market demands. The scattered distribution among angiosperms drew researchers' attention. The aim of this review is to appra...

journal_title：Fitoterapia

authors： Pu X,Zhang CR,Zhu L,Li QL,Huang QM,Zhang L,Luo YG

更新日期：2019-04-01 00:00:00

abstract：:Five new limonoids, named sundarbanxylogranins A-E (1-5), were isolated from the seeds of an Indian mangrove, Xylocarpus granatum, collected from mangrove swamps of the Sundarbans, India. The structures of these limonoids were established by HRESIMS and NMR spectroscopic data. Sundarbanxylogranin A (1) is a rare limon...

journal_title：Fitoterapia

authors： Dai YG,Wu J,Padmakumar KP,Shen L

更新日期：2017-10-01 00:00:00

abstract：:The first chemical examination of roots of the traditionally used medicinal plant Talinum triangulare (Portulacaceae) from Nigeria led to the isolation of two new C-methylated flavonoids, 5,6-dimethoxy-7-hydroxy-8-methyl-flavone (1), 5,6-dimethoxy-8-methyl-2-phenyl-7H-1-benzopyran-7-one (2), and one new α-pyrone deriv...

journal_title：Fitoterapia

authors： Umeokoli BO,Muharini R,Okoye FB,Ajiwe VI,Akpuaka MU,Lin W,Liu Z,Proksch P

更新日期：2016-03-01 00:00:00

abstract：:Four new eburnamine-aspidospermine type bisindole alkaloids, namely, mekongenines C-F (1-4), along with 27 known indole alkaloids were isolated from the twigs and leaves of Bousigonia mekongensis. Their structures with the absolute configurations were elucidated by spectroscopic methods and ECD analyses. All new compo...

journal_title：Fitoterapia

authors： Fu YH,Li SL,Li SF,He HP,Di YT,Zhang Y,Hao XJ

更新日期：2014-10-01 00:00:00

abstract：:Caper (Capparis L.), a shrub plant with a large natural distribution, is used in traditional medicines to cure various illnesses. Phytochemicals studies have shown the presence of many beneficial compounds such as spermidine, rutin, quercetin, kaempferol, stigmasterol, campesterol, tocopherols, and carotenoids. Biolog...

journal_title：Fitoterapia

authors： Tlili N,Elfalleh W,Saadaoui E,Khaldi A,Triki S,Nasri N

更新日期：2011-03-01 00:00:00