Abstract:
:Four new cycloartane triterpenoids, 1α,3β-dihydroxy-16-keto-24(31)-en-cycloartane (1), 31-methoxyl-passifloic acid (2), cyclopassifloside XIV (3), and cyclopassifloside XV (4), together with six known compounds (5-10) were isolated from Passiflora edulis Sims. Their structures were elucidated on the basis of extensive spectroscopic analysis. All the compounds were evaluated for protective effects against damage of PC12 cell induced by glutamate according to traditional usage of the herbal medicine, and the results indicated that cycloartane triterpenoids maybe one of the active compositions of P. edulis Sims for the treatment of neurodegenerative disease.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Xu FQ,Wang N,Fan WW,Zi CT,Zhao HS,Hu JM,Zhou Jdoi
10.1016/j.fitote.2016.09.013subject
Has Abstractpub_date
2016-12-01 00:00:00pages
122-127eissn
0367-326Xissn
1873-6971pii
S0367-326X(16)30450-6journal_volume
115pub_type
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