Abstract:
:The cytotoxic effects of seven constituents isolated from Duguetia glabriuscula were evaluated against Hep2 human larynx carcinoma cells. The cytotoxicity exhibited by beta-sitosterol was as strong as that of cis-platin. (+)-Alloaromadendran-10,14beta-diol caused inhibition of cellular growth with IC50 values lower than 25 microg/ml, a feature that was considered as revealing significant activity. Polycarpol showed borderline cytotoxicity, whereas the other compounds were inactive.
journal_name
Fitoterapiajournal_title
Fitoterapiaauthors
Matos MF,Leite LI,Brustolim D,de Siqueira JM,Carollo CA,Hellmann AR,Pereira NF,da Silva DBdoi
10.1016/j.fitote.2006.01.013keywords:
subject
Has Abstractpub_date
2006-04-01 00:00:00pages
227-9issue
3eissn
0367-326Xissn
1873-6971pii
S0367-326X(06)00041-4journal_volume
77pub_type
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