Abstract:
:In reporter-based transient expression systems, we characterized simian immunodeficiency virus from a chimpanzee (SIVCPZ), with special reference to the human immunodeficiency virus type 1 (HIV-1). SIVCPZ was not equally activated by tat and rev transactivators derived from representative primate lentiviruses. HIV-1 alone activated SIVCPZ to the full extent in both tat and rev assays. The tat and rev gene products of SIVCPZ, as well as those of HIV-1, efficiently transactivated the other viruses. These results indicate that SIVCPZ is identical to HIV-1 with regard to the compatibility of tat and rev gene activities among four subgroups of primate lentiviruses.
journal_name
Virologyjournal_title
Virologyauthors
Sakuragi J,Sakai H,Sakuragi S,Shibata R,Wain-Hobson S,Hayami M,Adachi Adoi
10.1016/0042-6822(92)90715-2subject
Has Abstractpub_date
1992-07-01 00:00:00pages
354-8issue
1eissn
0042-6822issn
1096-0341journal_volume
189pub_type
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