Effect of tunicamycin on the structural proteins and infectivity of budded Autographa californica nuclear polyhedrosis virus.

abstract：:We previously showed that reduced infectivity of HIV with incompletely processed capsid-spacer protein 1 (CA-SP1) is rescued by cellular activation or increased expression of HSP90AB1, a member of the cytosolic heat shock protein 90 family. Here we show that HSP90AB1 is present in HIV virions and that HSP90AB1, but no...

journal_title：Virology

authors： Joshi P,Sloan B,Torbett BE,Stoddart CA

更新日期：2013-02-05 00:00:00

abstract：:Many virus-encoded RGD-containing proteins have been reported to play important roles in virus attachment and entry. Here we report the identification and functional characterization of a gene encoding an RGD-containing protein (037L) from large yellow croaker iridovirus (LYCIV), a causative agent of epizootics among ...

journal_title：Virology

authors： Ao J,Chen X

更新日期：2006-11-25 00:00:00

abstract：:We developed a positive selection method for recovering Marek's disease virus (MDV) recombinants. The Escherichia coli xanthine-guanine phosphoribosyltransferase gene (gpt), under the control of the major immediate-early promoter from cytomegalovirus, was inserted into the inverted repeats flanking the unique long (UL...

journal_title：Virology

authors： Marshall DR,Reilly JD,Liu X,Silva RF

更新日期：1993-08-01 00:00:00

abstract：:The Autographa californica nuclear polyhedrosis virus da26 gene codes for an envelope protein of both budded virus (BV) and occlusion derived virus (ODV). Western blot and temporal analysis of infected cell extracts detected a protein of 26 kDa by 4 h postinfection (p.i.). The amount of protein increased by 16 h p.i. ...

journal_title：Virology

authors： Beniya H,Braunagel SC,Summers MD

更新日期：1998-01-05 00:00:00

abstract：:The unordered N-termini of parvovirus capsid proteins (Nt) are translocated through a channel at the icosahedral five-fold axis to serve for virus traffick. Heterologous peptides were genetically inserted at the Nt of MVM to study their functional tolerance to manipulations. Insertion of a 5T4-single-chain antibody at...

journal_title：Virology

authors： Sánchez-Martínez C,Grueso E,Carroll M,Rommelaere J,Almendral JM

更新日期：2012-10-10 00:00:00

abstract：:Sequence analysis of the mouse hepatitis virus, strain A59 (MHV-A59) genome predicts the presence of two papain-like proteinases encoded within the first open reading frame (ORF 1a) of the replicase gene. The more 5' of these domains, the leader papain-like proteinase, is responsible for the cleavage of the amino term...

journal_title：Virology

authors： Bonilla PJ,Hughes SA,Piñón JD,Weiss SR

更新日期：1995-06-01 00:00:00

abstract：:Equine infectious anemia virus (EIAV) is responsible of acute disease episodes characterized by fever, anemia, thrombocytopenia and anorexia in equids. The high mutation rate in EIAV genome limited the number of full genome sequences availability. In the present study, we used the SureSelect target enrichment system w...

journal_title：Virology

authors： Deshiere A,Berthet N,Lecouturier F,Gaudaire D,Hans A

更新日期：2019-11-01 00:00:00

abstract：:The lung-derived dendritic cell (LDC) recruitment following intranasal (i.n.) vaccination of different poxviral vector-based vaccines/adjuvants were evaluated to decipher how these factors influenced CD8(+) T cell avidity. Compared to the standard i.n. recombinant fowlpox virus (FPV)-HIV vaccination, the FPV-HIV IL-13...

journal_title：Virology

authors： Trivedi S,Jackson RJ,Ranasinghe C

更新日期：2014-11-01 00:00:00

abstract：:Peste des petits ruminants (PPR) is a viral disease of goats and sheep characterized by erosive stomatitis, enteritis, and pneumonia. The virus is a member of the family Paramyxoviridae and the genus Morbillivirus. The disease has high morbidity and mortality rates and has a substantial economic impact in developing c...

journal_title：Virology

authors： Ismail TM,Yamanaka MK,Saliki JT,el-Kholy A,Mebus C,Yilma T

更新日期：1995-04-20 00:00:00

abstract：:A reporting replicon of West Nile virus (WN) was used to distinguish between the function of the 3' untranslated region (UTR) in viral translation and RNA replication. Deletions of various regions of the 3' UTR of the replicon did not significantly affect viral translation, but abolished RNA replication. A systematic ...

journal_title：Virology

authors： Tilgner M,Deas TS,Shi PY

更新日期：2005-01-20 00:00:00

abstract：:We compared the in vitro fidelity of wild-type human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) and the prototype foamy virus (PFV) RT. Both enzymes had similar error rates for single nucleotide substitutions; however, PFV RT did not appear to make errors at specific hotspots, like HIV-1 RT. In a...

journal_title：Virology

authors： Boyer PL,Stenbak CR,Hoberman D,Linial ML,Hughes SH

更新日期：2007-10-25 00:00:00

abstract：:Picornavirus RNA translation is driven by the internal ribosome entry site (IRES) element. The impact of RNA structure on the foot-and-mouth disease virus (FMDV) IRES activity has been analyzed using Selective 2'Hydroxyl Acylation analyzed by Primer Extension (SHAPE) and high throughput analysis of RNA conformation by...

journal_title：Virology

authors： Fernández N,García-Sacristán A,Ramajo J,Briones C,Martínez-Salas E

更新日期：2011-01-20 00:00:00

abstract：:Covalently closed circular dimers of phage lambda DNA have been found in Escherichia coli infected with lambda. These dimers can be formed by either the lambda Red or Int systems, by a nonrecombinational replicative mechanism requiring the activity of the lambda O and P genes or by joining of the cohesive ends. Dimers...

journal_title：Virology

authors： Freifelder D,Baran N,Folkmanis A,Freifelder DL

更新日期：1977-09-01 00:00:00

abstract：:Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amin...

journal_title：Virology

authors： Schoppel K,Hassfurther E,Britt W,Ohlin M,Borrebaeck CA,Mach M

更新日期：1996-02-01 00:00:00

abstract：:The RNA dependent RNA polymerase of Sendai virus consists of a complex of the large (L) and phosphoprotein (P) subunits where L is thought to be responsible for all the catalytic activities necessary for viral RNA synthesis. We previously showed that the L protein forms an oligomer [Smallwood, S., Cevik, B., Moyer, S....

journal_title：Virology

authors： Cevik B,Smallwood S,Moyer SA

更新日期：2007-06-20 00:00:00

abstract：:Resting peripheral blood mononuclear cells (PBMC) or purified T-cells can be induced to proliferate when cocultured in vitro with fixed HTLV-infected T-cells. This process of HTLV-dependent cellular activation and induction of proliferation has been considered distinctive because of an apparent independence from conve...

journal_title：Virology

authors： Martin TC,Southern PJ

更新日期：1996-07-15 00:00:00

abstract：:Maize streak virus (MSV) is a leafhopper-transmitted geminivirus containing one molecule of circular single-stranded DNA of about 2.7 kb. We have tested the infectivity of MSV mutants. A deletion of 29 bases in the small intergenic region (SIR) did not affect the infectivity of MSV. Mutants containing insertions of ol...

journal_title：Virology

authors： Shen WH,Hohn B

更新日期：1991-08-01 00:00:00

abstract：:Mutants of the influenza virus A/seal/Mass/1/80 (H7N7) are described which contain an insertion of 60 nucleotides in the hemagglutinin (HA) gene, derived most probably by recombination between the HA gene and the nucleoprotein gene of the same virus. The nonhomologous RNA recombination resulted in an enhanced hemagglu...

journal_title：Virology

authors： Orlich M,Gottwald H,Rott R

更新日期：1994-10-01 00:00:00

abstract：:The interaction between the viral envelope protein gp120 and the cellular surface antigen CD4 is a key event in HIV-1 infection. Reciprocal high affinity binding sites have been located in the first domain of CD4 and in the carboxy-terminal region of gp120, respectively. Upon infection, the membranes of the target cel...

journal_title：Virology

authors： Autiero M,Abrescia P,Dettin M,Di Bello C,Guardiola J

更新日期：1991-12-01 00:00:00

abstract：:In an attempt to develop an in vitro human cytomegalovirus (HCMV) latency model system, the growth characteristics of HCMV in a human thyroid papillary carcinoma cell line (TPC-1) were examined. When TPC-1 cultures preheated at 40.5 degrees for 48 hr were infected with HCMV and incubated at a supraoptimal temperature ...

journal_title：Virology

authors： Tanaka J,Ogura T,Sato H,Hatano M

更新日期：1987-11-01 00:00:00

abstract：:The lentivirus caprine arthritis-encephalitis virus (CAEV) is closely related by nucleotide sequence homology to visna virus and other sheep lentiviruses and shows less similarity to the other animal and human lentiviruses. The genomic organization of CAEV is very similar to that of visna virus and the South African o...

journal_title：Virology

authors： Saltarelli M,Querat G,Konings DA,Vigne R,Clements JE

更新日期：1990-11-01 00:00:00

abstract：:The results of a previous study suggested that the poly(A) sequence in barley stripe mosaic virus (BSMV) RNA is intercalated between a 3'-terminal tyrosine-accepting structure and the 5'-terminal coding part of the BSMV genome. Here we show that poly(A)+ and poly(A)- fractions of BSMV RNA can be cleaved into two fragm...

journal_title：Virology

authors： Agranovsky AA,Dolja VV,Atabekov JG

更新日期：1982-05-01 00:00:00

abstract：:To determine whether infection with HIV-1 strains of different tropisms would influence expression of the mucosa-associated integrins alpha 4 beta 7 and alpha E beta 7 or the lymph node homing receptor L-selectin on peripheral T lymphocytes, cells were infected with the CXCR4-tropic (X4)/syncytium-inducing (SI) HIV-1(...

journal_title：Virology

authors： Cummins JE Jr,Bunn WJ,Hall SD,Donze HH,Mestecky J,Jackson S

更新日期：2001-02-15 00:00:00

abstract：:About 100 nucleotides of DNA sequence at the 5' noncoding region of the Choristoneura biennis entomopoxvirus spheroidin gene was chemically synthesized and inserted into a vaccinia expression vector, interrupting the vaccinia thymidine kinase gene. When the bacterial beta-galactosidase gene was introduced downstream o...

journal_title：Virology

authors： Pearson A,Richardson C,Yuen L

更新日期：1991-02-01 00:00:00

abstract：:An insertion mutation in the pol gene of Moloney murine leukemia virus (M-MuLV) was found to render the virus temperature-sensitive for replication. A provirus containing a 12-bp insertion at the boundary between the reverse transcriptase (RT) and integrase (IN) domains induced the formation of mutant virions containi...

journal_title：Virology

authors： Tanese N,Roth M,Epstein H,Goff SP

更新日期：1989-06-01 00:00:00

abstract：:While HPV 16 variant lineages have been well characterized, the knowledge about HPV 18 variants is limited. In this study, HPV 18 nucleotide variations in the E2 hinge region were characterized by sequence analysis in 47 control and 51 tumor specimens. Fifty of these specimens were randomly selected for sequencing of ...

journal_title：Virology

authors： Arias-Pulido H,Peyton CL,Torrez-Martínez N,Anderson DN,Wheeler CM

更新日期：2005-07-20 00:00:00

abstract：:Primary duck hepatocytes maintained in serum-free culture medium containing dimethyl sulfoxide support efficient replication of duck hepatitis B virus following infection in vitro. Cells remain susceptible to infection for at least 2 weeks after plating, allowing spread of virus via repeat cycles of infection. Up to 1...

journal_title：Virology

authors： Pugh JC,Summers JW

更新日期：1989-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) core protein constitutes a viral nucleocapsid and may possess multiple functions. In this study, we demonstrated the homotypic interaction and multimerization of HCV core protein in vitro and in vivo. By using a yeast two-hybrid system, we showed that the amino-terminal hydrophilic portion (ami...

journal_title：Virology

authors： Matsumoto M,Hwang SB,Jeng KS,Zhu N,Lai MM

更新日期：1996-04-01 00:00:00

abstract：:The genome of peanut clump pecluvirus (PCV) consists of two messenger RNA components which contain, respectively, three and five open reading frames (ORFs). Inoculation of transcripts from full-length cDNA clones derived from the PCV RNAs showed that RNA-1 is able to replicate in the absence of RNA-2 in protoplasts, b...

journal_title：Virology

authors： Herzog E,Hemmer O,Hauser S,Meyer G,Bouzoubaa S,Fritsch C

更新日期：1998-09-01 00:00:00

abstract：:Evidence is presented for the glycosylation of the cauliflower mosaic virus (CaMV) capsid polypeptide. Fluorescent derivatives of concanavalin A (Con A) were shown to bind specifically to the dissociated CaMV capsid polypeptides in polyacrylamide gels. Con A also bound specifically to intact CaMV, so inhibiting the at...

journal_title：Virology

authors： Du Plessis DH,Smith P

更新日期：1981-03-01 00:00:00