Abstract:
:Covalently closed circular dimers of phage lambda DNA have been found in Escherichia coli infected with lambda. These dimers can be formed by either the lambda Red or Int systems, by a nonrecombinational replicative mechanism requiring the activity of the lambda O and P genes or by joining of the cohesive ends. Dimers mediated by the E. coli Rec system have not been observed. Those formed by the Int system often result from recombination between different DNA molecules; however, the Red-mediated dimers may be a result of replicative extension of a single DNA molecule. Trimers have also been observed but studied only briefly.
journal_name
Virologyjournal_title
Virologyauthors
Freifelder D,Baran N,Folkmanis A,Freifelder DLdoi
10.1016/0042-6822(77)90136-2subject
Has Abstractpub_date
1977-09-01 00:00:00pages
183-91issue
2eissn
0042-6822issn
1096-0341journal_volume
81pub_type
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