Abstract:
:The Chlorella virus PBCV-1 genome is a linear nonpermuted 333-kbp dsDNA molecule with covalently closed hairpin termini. The termini (minus the hairpin) are identical inverted repeats of at least 2185 bases after which the sequence diverges. The inverted repeats contain two small potential open reading frames and several direct repeats. However, neither the open reading frames nor the remainder of the inverted repeats are transcribed during PBCV-1 replication. Twenty-nine other Chlorella virus DNAs, of 36 tested, hybridized to the PBCV-1 terminal fragments.
journal_name
Virologyjournal_title
Virologyauthors
Strasser P,Zhang YP,Rohozinski J,Van Etten JLdoi
10.1016/0042-6822(91)90089-tsubject
Has Abstractpub_date
1991-02-01 00:00:00pages
763-9issue
2eissn
0042-6822issn
1096-0341journal_volume
180pub_type
杂志文章相关文献
VIROLOGY文献大全abstract::The nucleocapsids of many plant viruses are significantly more robust and protective of their RNA contents than those of enveloped animal viruses. In particular, the capsid protein (CP) of the plant virus Cowpea Chlorotic Mottle Virus (CCMV) is of special interest because it has been shown to spontaneously package, wi...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2013.03.001
更新日期:2013-06-20 00:00:00
abstract::Rice tungro bacilliform virus (RTBV) is a plant pararetrovirus and a member of the Caulimoviridae family and closely related to viruses in the Badnavirus genus. The coat protein of RTBV is part of the large polyprotein encoded by open reading frame 3 (ORF3). ORF3 of an RTBV isolate from Malaysia was sequenced (accessi...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1998.9519
更新日期:1999-01-20 00:00:00
abstract::Maturation of the arenavirus GP precursor (GPC) involves proteolytic processing by cellular signal peptidase and the proprotein convertase subtilisin kexin isozyme 1 (SKI-1)/site 1 protease (S1P), yielding a tripartite complex comprised of a stable signal peptide (SSP), the receptor-binding GP1, and the fusion-active ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2012.10.038
更新日期:2013-02-05 00:00:00
abstract::Differing reports exist about the replication of human enteric adenoviruses (EnAds) in various cell lines. There was a suggestion that EnAds are defective, do not grow on primary human diploid cells, and behave like Ad host-range mutants, i.e., they require early gene products from other Ad types for efficient growth....
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(90)90072-y
更新日期:1990-01-01 00:00:00
abstract::Fixed rabies virus strains (ERA and CVS) produce a fatal paralytic disease in mice after intracerebral or intramuscular injection. Some antigenic mutants of both CVS and ERA viruses with a substitution in position 333 of the glycoprotein (arginine is replaced either by a glutamine, a glycine, or an isoleucine) are tot...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(89)90122-0
更新日期:1989-09-01 00:00:00
abstract::We previously demonstrated in trials of a variety of experimental vaccines to equine infectious anemia virus (EIAV) a remarkable spectrum of efficacy ranging from sterilizing protection to severe enhancement of virus replication and disease, depending on the immunization strategy used. This range of vaccine efficacy o...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1999.9939
更新日期:1999-09-30 00:00:00
abstract::The human T cell leukemia virus type I (HTLV-I) is an oncogenic retrovirus that is etiologically linked to the genesis of adult T cell leukemia (ATL) as well as HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Emerging evidence suggests that the pathogenicity of HTLV-I involves deregulated activati...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2004.12.008
更新日期:2005-03-01 00:00:00
abstract::Feline calicivirus depends on host-cell proteins for its replication. We previously showed that knockdown of nucleolin (NCL), a phosphoprotein involved in ribosome biogenesis, resulted in the reduction of FCV protein synthesis and virus yield. Here, we found that NCL may not be involved in FCV binding and entry into c...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2015.12.001
更新日期:2016-02-01 00:00:00
abstract::Rotaviral RNA was detected in the stool sample of an asymptomatic fattening pig at a Slovenian pig farm. To characterize the rotavirus, RT-PCR was used, employing primers specific for the VP7, VP4 and NSP4 genes. Specific products were purified and the sequencing reaction was performed for the molecular analysis of am...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2006.10.001
更新日期:2007-03-15 00:00:00
abstract::Infection with a broad diversity of viruses often activates host cell signaling pathways including the mitogen-activated protein kinase pathway. The present study established that dengue virus infection of human macrophages activates Jun NH(2)-terminal kinase (JNK) and the p38 MAPKs pathways. The activation was observ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2009.10.019
更新日期:2010-01-05 00:00:00
abstract::Eight different human rotavirus strains were adapted to replicate in cell culture. In vitro, rotavirus genetic reassortment has been performed between two virus strains, one with a long pattern of segmented genomic RNAs and the other with a short pattern in the electrophoretic mobility of genomic RNAs. This genetic re...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(84)90381-7
更新日期:1984-12-01 00:00:00
abstract::Respiratory syncytial virus (RSV) induces the production of a number of cytokines and chemokines by activation of nuclear factor kappa B (NF-kappaB). The activation of NF-kappaB has been shown to depend on viral replication in the infected cells. In this study, we demonstrate that expression of RSV M2-1 protein, a tra...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2004.10.031
更新日期:2005-01-20 00:00:00
abstract::How the H7N9 avian influenza virus gained the distinct ability to infect humans is unclear. Pigs are an important host in influenza virus ecology because they are susceptible to infection with both avian and human influenza viruses and are often involved in interspecies transmission. Here, we passaged one avian isolat...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2014.01.016
更新日期:2014-03-01 00:00:00
abstract::Cytoplasmic tails of envelope (Env) glycoproteins of many retroviruses inhibit their membrane fusion activity. The cytoplasmic 16-amino acid peptide of ecotropic murine leukemia virus (E-MLV) Env protein, called the R-peptide, also inhibits the membrane fusion activity of the Env protein. However, the molecular mechan...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2019.04.005
更新日期:2019-06-01 00:00:00
abstract::Human papillomavirus type 27 (HPV-27) and HPV-2c are isolates of the same virus as judged by genomic sequence identity. In a 400-bp stretch of the long control region and the E6 and L1 genes no changes were found between HPV-27 and HPV-2c whereas 55 changes were found between HPV-27 and HPV-2a. This justifies the elev...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1994.1307
更新日期:1994-06-01 00:00:00
abstract::Transcription of human papillomaviruses (HPV) is regulated by enhancer sequences located in the upstream regulatory region. The factors regulating expression of one of the high risk genital HPV types, HPV 31b, were investigated using transient expression and protein binding assays. A region of 262 base pairs in length...
journal_title:Virology
pub_type: 杂志文章
doi:10.1006/viro.1995.1390
更新日期:1995-08-01 00:00:00
abstract::Revertants were isolated from the protease activation mutant of Sendai virus, F1-R, which causes a systemic infection in mice. The fusion (F) glycoprotein of F1-R is susceptible to activation cleavage by ubiquitous cellular proteases and is thus responsible for pantropism in mice (Tashiro et al., 1988. Virology 165, 5...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(91)90839-4
更新日期:1991-09-01 00:00:00
abstract::Ovarian cancer is the third most common female cancer, with poor survival in later stages of metastatic spread. We test a chimeric virus consisting of genes from Lassa and vesicular stomatitis viruses, LASV-VSV; the native VSV glycoprotein is replaced by the Lassa glycoprotein, greatly reducing neurotropism. Human ova...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2020.10.009
更新日期:2020-11-12 00:00:00
abstract::We compared the levels of the Ski oncoprotein, an inhibitor of transforming growth factor-beta (TGF-β) signaling, in normal human keratinocytes (HKc), HPV16 immortalized HKc (HKc/HPV16), and differentiation resistant HKc/HPV16 (HKc/DR) in the absence and presence of TGF-β. Steady-state Ski protein levels increased in ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2013.05.039
更新日期:2013-09-01 00:00:00
abstract::Mannose binding lectin (MBL) generally plays a protective role during viral infection, yet MBL-mediated complement activation promotes Ross River virus (RRV)-induced inflammatory tissue destruction, contributing to arthritis and myositis. As MBL binds to carbohydrates, we hypothesized that N-linked glycans on the RRV ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2017.12.022
更新日期:2018-02-01 00:00:00
abstract::Two small viral proteins (DGBp1 and DGBp2) have been proposed to act in a concerted manner to aid intra- and intercellular trafficking of carmoviruses though the distribution of functions and mode of action of each protein partner are not yet clear. Here we have confirmed the requirement of the DGBps of Pelargonium fl...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2011.03.001
更新日期:2011-05-10 00:00:00
abstract::The 3' untranslated regions (UTRs) of many plant viral RNAs contain cap-independent translation elements (3' CITEs). Among the 3' CITEs, the Barley yellow dwarf virus (BYDV)-like translation elements (BTEs) form a structurally variable and widely distributed group. Viruses in three genera were known to harbor 3' BTEs,...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2010.03.025
更新日期:2010-06-20 00:00:00
abstract::The nucleotide sequence of the env gene of a previously described human provirus (ERV3) has been determined beginning near the 3'-end of the pol gene and continuing through the 3'-LTR. Analysis of the nucleotide sequence revealed the presence of a long open reading frame of 1944 nucleotides that is capable of encoding...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(85)90147-3
更新日期:1985-12-01 00:00:00
abstract::To determine the role of piscine anti-viral cytotoxic cells, we analyzed the response of channel catfish to Ictalurid herpesvirus 1, commonly designated channel catfish virus (CCV). Peripheral blood leukocytes (PBL) from catfish immunized with MHC-matched, CCV-infected G14D cells (G14D-CCV) showed marked lysis of G14D...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2019.11.014
更新日期:2020-01-15 00:00:00
abstract::Dipeptidyl peptidase 4 (DPP4) is a receptor for MERS-CoV. The soluble form of DPP4 (sDPP4) circulates systematically and can competitively inhibit MERS-CoV entry into host cells. Here, we measured the concentration of sDPP4 in the plasma and sputa of 14 MERS-CoV-infected patients of various degrees of disease severity...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2018.03.015
更新日期:2018-05-01 00:00:00
abstract::The tegument protein pp28 of human cytomegalovirus (HCMV) is essential for the assembly of infectious HCMV virions, but how it functions during the process of HCMV tegumentation and envelopment remains unclear. By using live cell fluorescence resonance energy transfer (FRET) microscopy and yeast two-hybrid assays, we ...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2009.03.007
更新日期:2009-05-25 00:00:00
abstract::The interferon (IFN) activity found in human leukocyte IFN alpha preparations, autoimmune and AIDS sera, and others was reported to have distinct antigenic and deviating biological properties. This led to its vague designation as acid-labile and thermolabile IFN alpha. However, using specific monoclonal antibodies, th...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/0042-6822(91)90517-f
更新日期:1991-03-01 00:00:00
abstract::The recently described taxon Negevirus is comprised of a diverse group of insect-specific viruses isolated from mosquitoes and phlebotomine sandflies. In this study, a comprehensive genetic characterization, molecular, epidemiological and evolutionary analyses were conducted on nearly full-length sequences of 91 new n...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2017.01.022
更新日期:2017-04-01 00:00:00
abstract::Human gammaherpesvirus 8 (HHV-8) is the etiologic agent of Kaposi's sarcoma, multicentric Castleman's disease and primary effusion lymphoma. Like other herpesviruses, the HHV-8 may exhibit latent or lytic cycle, both regulated by viral and host factors. Regarding host factors, we analysed the association of polymorphi...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2019.07.011
更新日期:2019-09-01 00:00:00
abstract::Hepatitis B virus synthesizes multiple spliced RNAs that can be reverse transcribed into viral DNA. We thoroughly characterized the contribution of spliced RNAs to DNA synthesis in transfected cultures of Huh7 and HepG2 cells. We found that up to 50% of DNA within intracellular capsids is derived from five spliced RNA...
journal_title:Virology
pub_type: 杂志文章
doi:10.1016/j.virol.2008.06.021
更新日期:2008-09-15 00:00:00