Structural plasticity of Barley yellow dwarf virus-like cap-independent translation elements in four genera of plant viral RNAs.

abstract：:Particles purified from the liver of hepatitis B virus-infected patients were previously shown by us to incorporate 32P-deoxynucleotides into viral DNA and DNA-RNA hybrid molecules when incubated in a DNA polymerase reaction mixture. In this investigation, similar particles from duck and ground squirrel livers infecte...

journal_title：Virology

authors： Miller RH,Marion PL,Robinson WS

更新日期：1984-11-01 00:00:00

abstract：:The rep gene of the defective human parvovirus, adeno-associated virus, (AAV) mediates several trans-acting functions important to virus replication, transcription, and gene expression. At least four overlapping polypeptides are expressed from the rep gene. We have constructed a prokaryotic vector which expressed in E...

journal_title：Virology

authors： Trempe JP,Mendelson E,Carter BJ

更新日期：1987-11-01 00:00:00

abstract：:Begomoviruses (family Geminiviridae) are responsible for many economically important crop diseases worldwide. The majority of these diseases are caused by bipartite begomovirus infections, although a rapidly growing number of diseases of the Old World are associated with monopartite begomoviruses. With the exception o...

journal_title：Virology

authors： Briddon RW,Stanley J

更新日期：2006-01-05 00:00:00

abstract：:In HSV types 1 and 2, gH forms a noncovalent heterodimer with gL. Previous studies demonstrated that the first 323 amino acids of gH1 and the first 161 amino acids of gL1 are sufficient for gH/gL binding. For gL1, substitution of any of its four cysteine (C) residues (all located within the gH/gL binding region) destr...

journal_title：Virology

authors： Cairns TM,Landsburg DJ,Whitbeck JC,Eisenberg RJ,Cohen GH

更新日期：2005-02-20 00:00:00

abstract：:The influenza virus mRNAs are structurally similar to cellular mRNAs nevertheless; the virus promotes selective translation of viral mRNAs despite the inhibition of host cell protein synthesis. The infection proceeds normally upon functional impairment of eIF4E cap-binding protein, but requires functional eIF4A helica...

journal_title：Virology

authors： Yángüez E,Rodriguez P,Goodfellow I,Nieto A

更新日期：2012-01-20 00:00:00

abstract：:This report shows that (S)CARNA 5, the satellite of cucumber mosaic virus (CMV) strain S, directs the synthesis of two small proteins in a wheat germ cell-free translation system. The two proteins are produced by the translation of both (S)CARNA 5 purified from CMV virions and the (+) strand purified from double-stran...

journal_title：Virology

authors： Avila-Rincon MJ,Collmer CW,Kaper JM

更新日期：1986-07-30 00:00:00

abstract：:About 38% of primary HIV-1 long terminal repeats (LTRs) contain an insertion (consensus: 5prime prime or minute-ACYGCTGA-3prime prime or minute), termed the most frequent naturally occurring length polymorphism (MFNLP). The MFNLP binds several transcription factors and might affect HIV-1 replication and disease progre...

journal_title：Virology

authors： Hiebenthal-Millow K,Kirchhoff F

更新日期：2002-01-05 00:00:00

abstract：:Activation of interferon regulatory factors (IRFs) 3 and 7 is essential for the induction of Type I interferons (IFN) and innate antiviral responses, and herpesviruses have evolved mechanisms to evade such responses. We previously reported that Epstein-Barr virus BZLF1, an immediate-early (IE) protein, inhibits the fu...

journal_title：Virology

authors： Bentz GL,Liu R,Hahn AM,Shackelford J,Pagano JS

更新日期：2010-06-20 00:00:00

abstract：:Mouse mammary tumour virus (MMTV) encodes a viral superantigen (Sag) and a negative acting factor (Naf) which share parts of their coding sequence. Using 2-dimensional gel electrophoresis (2D-DIGE), we could show that at least 10 different cellular proteins were differentially expressed in Naf positive cells. Also, lu...

journal_title：Virology

authors： Metzner C,Salmons B,Gunzburg WH,Gemeiner M,Miller I,Gesslbauer B,Kungl A,Dangerfield JA

更新日期：2006-03-01 00:00:00

abstract：:The tail sheath protein of giant bacteriophage phiKZ Pseudomonas aeruginosa encoded by gene 29 was identified and its expression system was developed. Localization of the protein on the virion was confirmed by immunoelectron microscopy. Properties of gene product (gp) 29 were studied by electron microscopy, immunoblot...

journal_title：Virology

authors： Kurochkina LP,Aksyuk AA,Sachkova MY,Sykilinda NN,Mesyanzhinov VV

更新日期：2009-12-20 00:00:00

abstract：:The v-erb B protein of avian erythroblastosis virus (AEV) possesses an associated protein kinase activity in vitro. Analysis of temperature-sensitive mutants, and nonconditional host range mutants of AEV demonstrated that there was no simple correlation between this autophosphorylation activity and the transformation ...

journal_title：Virology

authors： Hayman MJ,Kitchener G,Knight J,McMahon J,Watson R,Beug H

更新日期：1986-04-15 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) Rev is a 19-kDa regulatory protein which binds to unspliced and partially spliced HIV-1 RNAs. Export, splicing, stability, and translation of HIV-1 RNAs are influenced by Rev. To further understand the effect of Rev on HIV-1 RNA splicing, the intranuclear localization of uns...

journal_title：Virology

authors： Favaro JP,Borg KT,Arrigo SJ,Schmidt MG

更新日期：1998-09-30 00:00:00

abstract：:Infection with many viruses results in the selective shutoff of host protein synthesis. A common target for virus interference with host protein synthesis is the cap-binding protein complex, eIF4F. The large subunit of the complex, eIF4G, is cleaved upon picornavirus (except cardiovirus) infection. Infection with aden...

journal_title：Virology

authors： Gingras AC,Sonenberg N

更新日期：1997-10-13 00:00:00

abstract：:Strong evidence indicates that virions of mammalian reoviruses undergo proteolytic processing by acid-dependent cellular proteinases as an essential step in productive infection. Proteolytic processing takes the form of a series of cleavages of outer-capsid proteins final sigma3 and mu1/mu1C. Previous studies showed a...

journal_title：Virology

authors： Kothandaraman S,Hebert MC,Raines RT,Nibert ML

更新日期：1998-11-25 00:00:00

abstract：:In this report, we present the DNA sequence and transcriptional characterization of a gene (IR5) that maps within each of the inverted repeat (IR) segments of the equine herpesvirus type 1 (EHV-1) genome. The IR5 open reading frame (ORF) is located within both IR sequences (nucleotides 9932-10,642 of the IR). DNA sequ...

journal_title：Virology

authors： Holden VR,Yalamanchili RR,Harty RN,O'Callaghan DJ

更新日期：1992-06-01 00:00:00

abstract：:Human papillomavirus type 16 (HPV-16) is the most common papillomavirus genome found in human cervical cancers and its DNA is capable of immortalizing primary keratinocytes in vitro. When expressed by their native promoter, two separate HPV-16 oncogenes, E6 and E7, cooperate to immortalize primary human keratinocytes....

journal_title：Virology

authors： Stöppler MC,Straight SW,Tsao G,Schlegel R,McCance DJ

更新日期：1996-09-01 00:00:00

abstract：:Mouse hybridomas which produce monoclonal antibodies to the Autographa californica nuclear polyhedrosis virus (AcNPV) have been prepared and the protein to which each is directed has been determined. The antibody produced by clones 3F3 and 5E9 specifically bound polyhedron protein of MW 32,000 when used in immunoadsor...

journal_title：Virology

authors： Roberts PL,Naser W

更新日期：1982-10-30 00:00:00

abstract：:Gibbon ape leukemia virus (GaLV) is a highly oncogenic C-type retrovirus capable of inducing myeloid leukemia in juvenile gibbons. GaLV is antigenically most closely related to a new world monkey virus, simian sarcoma associated virus (SSAV), and less to the murine and feline C-type leukemia viruses. To begin to under...

journal_title：Virology

authors： Delassus S,Sonigo P,Wain-Hobson S

更新日期：1989-11-01 00:00:00

abstract：:A nonhemagglutinating mutant of a 1978 isolate of canine parvovirus (CPV) was derived after repeated passages in the NLFK feline kidney cell line. The mutant CPV was antigenically indistinguishable from wild-type virus when tested with 82 monoclonal antibodies, and it replicated in cat and dog cell lines in culture. S...

journal_title：Virology

authors： Parrish CR,Burtonboy G,Carmichael LE

更新日期：1988-03-01 00:00:00

abstract：:The single-stranded DNA-binding protein LEF-3 of Autographa californica multinucleocapsid nucleopolyhedrovirus consists of 385 amino acid residues, forms oligomers, and promotes Mg2+-independent unwinding of DNA duplexes and annealing of complementary DNA strands. Partial proteolysis revealed that the DNA-binding doma...

journal_title：Virology

authors： Mikhailov VS,Okano K,Rohrmann GF

更新日期：2006-03-15 00:00:00

abstract：:Simian virus (SV40) T antigen shares many characteristics with adenovirus E1A which is known to induce apoptosis. To verify the potential of SV40 T antigen-mediated apoptosis, we stably expressed T antigen in immortalized human epithelial cells (Z172 and HaCaT). We found that SV40 T antigen could directly cause apopto...

journal_title：Virology

authors： Chen SL,Tsao YP,Chen YL,Huang SJ,Chang JL,Wu SF

更新日期：1998-05-10 00:00:00

abstract：:Altered cytokine profiles and imbalanced frequencies of CD4(+) T helper cell subsets are thought to be linked with HIV-1/AIDS pathogenesis, but the causes need to be further clarified. Histamine, a biogenic amine with many functions, shows enhancement in HIV-1 infected individuals, which are considered to link with di...

journal_title：Virology

authors： Zhai RR,Jiang AP,Wang HB,Ma L,Ren XX,Jiang JF,Wu L,Wei JF,Wang JH

更新日期：2013-08-01 00:00:00

abstract：:Cucumber seedlings infected with cucumber mosaic virus (CMV) contain a virus-induced RNA-dependent RNA polymerase (RNA replicase) in both soluble and particulate fractions of plant extracts; no such activity is found in uninfected plants. The extensive purification and characterization of the soluble RNA replicase has...

journal_title：Virology

authors： Gill DS,Kumarasamy R,Symons RH

更新日期：1981-08-01 00:00:00

abstract：:The CD4+ T-cell-restricted recognition of the structural proteins in the JHM strain of MHV (JHMV) was compared between two mouse strains. Following immunization with inactivated JHMV, all proteins elicited an immune response in both C57BL/6 and BALB/c mouse strains, except the nucleocapsid (N) protein, which was not i...

journal_title：Virology

authors： van der Veen RC

更新日期：1996-11-15 00:00:00

abstract：:We analyzed various mutants of tomato leaf curl virus-India to investigate the role of ORFs AV3, AV2, and coat protein (CP) in viral replication, movement, and symptom development. The results of these studies indicate that ORF AV3 does not encode a protein. Plants inoculated with infectious DNA which contained deleti...

journal_title：Virology

authors： Padidam M,Beachy RN,Fauquet CM

更新日期：1996-10-15 00:00:00

abstract：:We have determined the nucleotide sequence of the RNA2 segment of the Nudaurelia capensis omega virus genome. It was found to consist of 2448 nucleotides and contained one long open reading frame (ORF) encoding the 644 residue capsid protein. The deduced amino acid sequence of this protein reveals a positively charged...

journal_title：Virology

authors： Agrawal DK,Johnson JE

更新日期：1992-10-01 00:00:00

abstract：:Recent findings suggested that the SUMO-interacting motifs (SIMs) present in the human TRIM5α (TRIM5α(hu)) protein play an important role in the ability of TRIM5α(hu) to restrict N-MLV. Here we explored the role of SIMs in the ability of rhesus TRIM5α (TRIM5α(rh)) to restrict HIV-1, and found that TRIM5α(rh) SIM mutan...

journal_title：Virology

authors： Brandariz-Nuñez A,Roa A,Valle-Casuso JC,Biris N,Ivanov D,Diaz-Griffero F

更新日期：2013-01-20 00:00:00

abstract：:Transcription of human papillomaviruses (HPV) is regulated by enhancer sequences located in the upstream regulatory region. The factors regulating expression of one of the high risk genital HPV types, HPV 31b, were investigated using transient expression and protein binding assays. A region of 262 base pairs in length...

journal_title：Virology

authors： Kyo S,Tam A,Laimins LA

更新日期：1995-08-01 00:00:00

abstract：:Here, we evaluated the role of two host proteins, a Bromo domain containing RNA binding protein (BRP1) and Glyceraldehyde 3-phosphate dehydrogenase (GAPDH), in the replication of Cucumber mosaic virus (CMV). LC-MS/MS analysis of host/viral proteins pull down against BRP1 from CMV-infected plants co-infiltrated with BR...

journal_title：Virology

authors： Chaturvedi S,Seo JK,Rao AL

更新日期：2016-07-01 00:00:00

abstract：:LMP2A deletion and point mutants, with mutations in phosphotyrosine-containing protein-protein interaction motifs, were transiently expressed in 293 cells and their phosphorylation was examined in immune complex kinase assays as well as in vivo. In vitro LMP2A phosphorylation depended on tyrosine 112. In vivo, mutatio...

journal_title：Virology

authors： Scholle F,Longnecker R,Raab-Traub N

更新日期：2001-12-20 00:00:00